Results 41 to 50 of about 699,229 (300)

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Effect of debris accumulation on scour evolution at bridge pier in bank proximity

open access: yesJournal of Hydrology and Hydromechanics, 2021
Large debris transported by flood affects scour features at bridge piers and increases the risks of structural failure. Geometric characteristics of the debris and the relative position of the pier with respect to the river bank are important parameters ...
Palermo Michele   +2 more
doaj   +1 more source

Numerical Study of Road Embankment Type Action on Shear Stress Around Skewed Bridge Abutment

open access: yesThe Baltic Journal of Road and Bridge Engineering, 2022
This paper investigates the effect of different geometries of approach embankments and guides banks on the flow pattern and bed shear stress values in the skewed bridges in the compound channel using three-dimensional numerical modelling.
Mahdi Asadi   +2 more
doaj   +1 more source

A Systematic Comparison of Alpha‐Synuclein Seed Amplification Assays for Increasing Reproducibility

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Seed amplification assays (SAAs) enable ultrasensitive detection of misfolded α‐synuclein across biofluids and tissues. Yet, heterogeneity in protocols limits cross‐study comparability and clinical translation. Here, we review α‐synuclein SAA methods and their performance across various biological matrices.
Manuela Amaral‐do‐Nascimento   +3 more
wiley   +1 more source

Survey of the Intermolecular Disulfide Bonds Observed in Protein Crystal Structures Deposited in the Protein Data Bank

open access: yesLife, 2022
About 5% of the disulfide bonds (DBs) observed in the Protein Data Bank bridge two protein chains. Several of their features were comprehensively analyzed, resulting in a structural atlas of the intermolecular DBs.
Oliviero Carugo
doaj   +1 more source

The Locks [PDF]

open access: yes, 2015
He came out into the sun. Spice of wood-dust hung over the line of shanties following the canal; it was the dust of their houses baking on the bare packed bank that scarcely lifted above the water Waiting passively behind the bridge.
Wood, Allyn
core   +1 more source

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

open access: yesArthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Strain‐Programmable Luminescent Adhesive Patch With Tartrazine‐Mediated Optical Skin Clearing for Photochemical Tissue Bonding

open access: yesAdvanced Functional Materials, EarlyView.
We propose a suture‐complementary approach that integrates optical skin clearing with a strain‐programmable luminescent adhesive patch. Hyaluronic acid promotes transdermal delivery of tartrazine to improve optical clearing and stabilizes its interaction with a photosensitizer. Optical clearing increases the penetration depth of visible light into skin,
Seong‐Jong Kim   +6 more
wiley   +1 more source

Analysis of Uneven Settlement of Long-Span Bridge Foundations Based on SBAS-InSAR

open access: yesRemote Sensing
Bridge foundation settlement monitoring is crucial for infrastructure safety management, as uneven settlement can lead to stress redistribution, structural damage, and potentially catastrophic collapse.
Kaixuan Zhang   +7 more
doaj   +1 more source

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