Results 31 to 40 of about 991,648 (248)

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Experimental Investigation of the Detection of Bridge Dynamic Parameters Using a Moiving Vehicle [PDF]

, 2012
23rd KKCNN Symposium on Civil Engineering, Taipei, November 13-15, 2010This paper investigates the feasibility of using an instrumented vehicle to detect bridge dynamic parameters, such as natural frequency and structural damping, in a scaled laboratory
McGetrick, P., O\u27Brien, Eugene J., O'Brien, Eugene J., Kim, Chul-Woo   +3 more
core   +1 more source

Analysis of bridge dynamic load test based on millimeter wave radar

Scientific Reports
This study proposes a millimeter-wave radar telemetry method for measuring bridge dynamic deflection, addressing limitations in traditional dynamic strain measurement methods.
Lei Qiao, Xing-Jia Xia, He Guo, Hao Song, Yu-Quan Feng, Thierno Aliou Ka   +5 more
doaj   +1 more source

Common practices in assessing conditions of concrete bridges

MATEC Web of Conferences, 2017
Bridge condition assessment is an essential step in bridge management. To ensure safety and serviceability of bridge infrastructure, accurate condition assessment is needed to provide basis for bridge Maintenance, Repair, and Replacement (MRR) decisions.
Alsharqawi Mohammed, Zayed Tarek, Abu Dabous Saleh   +2 more
doaj   +1 more source

Automated Recording of Bridge Inspection Data in the Pontis Format Final Report, HR-364 April 1995 [PDF]

, 1995
A large percentage of bridges in the state of Iowa are classified as structurally or fiinctionally deficient. These bridges annually compete for a share of Iowa's limited transportation budget. To avoid an increase in the number of deficient bridges, the

core  

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

The development of a bridge management system involving standardised scour inspection procedures and flood forecasting [PDF]

, 2020
Agencies charged with managing infrastructure face a difficult and very responsible task in managing their bridge stock. Historically, bridge management relied upon paper-based processing of information and the knowledge of engineering staff. However, if
Kerin, Igor
core   +1 more source

Assessment of Weathering Steel Bridge Performance in Iowa and Development of Inspection and Maintenance Techniques, RB17-012, 2013 [PDF]

, 2013
Weathering steel is commonly used as a cost-effective alternative for bridge superstructures, as the costs and environmental impacts associated with the maintenance/replacement of paint coatings are theoretically eliminated.

core  

microRNA‐7‐5p and α‐Synuclein SAA Predict Parkinson's Disease Phenoconversion

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Corroborate blood neuron‐derived extracellular vesicle (NDEV) alpha‐synuclein (αSyn), the CSF αSyn seed amplification assay (αSyn‐SAA), and blood microRNA‐7‐5p (miR‐7‐5p) as markers for Parkinson's disease (PD) phenoconversion and determine if combining these markers would help select subjects who would be more likely to phenoconvert.
Shayan Zadegan, Praveen Velammal, Kanmani Muthiah, Madhu Jatty, Christopher Adams   +4 more
wiley   +1 more source