Results 41 to 50 of about 402,320 (302)

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

open access: yesFEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young   +7 more
wiley   +1 more source

Performance-Based Ranking of Existing Road Bridges

open access: yesApplied Sciences, 2021
Bridge condition assessment in most European countries is based on visual inspection in combination with damage assessment of bridge components. For adequate bridge management, the assessment needs to be further developed to move from the bridge ...
Ana Mandić Ivanković   +3 more
doaj   +1 more source

Performance Evaluation of Inverted Tee (IT) Bridge System [PDF]

open access: yes, 2019
The Inverted Tee (IT) girder bridge system was originally developed in 1996 by the University of Nebraska–Lincoln (UNL) researchers and Nebraska Department of Transportation (NDOT) engineers.
Abo El-Khier, Mostafa   +5 more
core   +1 more source

Predicting Epileptogenic Tubers in Patients With Tuberous Sclerosis Complex Using a Fusion Model Integrating Lesion Network Mapping and Machine Learning

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Accurate localization of epileptogenic tubers (ETs) in patients with tuberous sclerosis complex (TSC) is essential but challenging, as these tubers lack distinct pathological or genetic markers to differentiate them from other cortical tubers.
Tinghong Liu   +11 more
wiley   +1 more source

Bridge College: inspection of FEFC-funded provision in non-sector establishments for students with learning difficulties and/or disabilities (Report from the Inspectorate, 1999-00) [PDF]

open access: yes, 2000
Independent Establishment 17/00, Inspection of FEFC-Funded Provision in non-sector establishments for students with learning difficulties and/or disabilities.

core  

Automated optical inspection of solder paste based on 2.5D visual images [PDF]

open access: yes, 2009
In this paper, a special technique for the inspection of solder paste using directional LED lighting is presented. Conventional optical inspection method would depend on an image acquired from a camera mounted from the top.
Chu, MH, Pang, GKH
core   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Common practices in assessing conditions of concrete bridges

open access: yesMATEC Web of Conferences, 2017
Bridge condition assessment is an essential step in bridge management. To ensure safety and serviceability of bridge infrastructure, accurate condition assessment is needed to provide basis for bridge Maintenance, Repair, and Replacement (MRR) decisions.
Alsharqawi Mohammed   +2 more
doaj   +1 more source

The HSS/SNiC : a conceptual framework for collapsing security down to the physical layer [PDF]

open access: yes, 2008
This work details the concept of a novel network security model called the Super NIC (SNIC) and a Hybrid Super Switch (HSS). The design will ultimately incorporate deep packet inspection (DPI), intrusion detection and prevention (IDS/IPS) functions, as ...
Binns, Richard   +2 more
core  

Sex Differences in Medication Discontinuation in Axial Spondyloarthritis

open access: yesArthritis Care &Research, EarlyView.
Objective We examined sex differences in medication discontinuation among patients with axial spondyloarthritis (axSpA) initiating tumor necrosis factor inhibitors (TNFi), interleukin‐17 inhibitors (IL‐17i), or JAK inhibitors (JAKi). Methods Using data from the Rheumatology Informatics System for Effectiveness (RISE) Registry (2003–2025), we assessed ...
Rachael Stovall   +9 more
wiley   +1 more source

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