Results 41 to 50 of about 2,121,605 (282)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Analysis of the core and bridge effects of interpersonal, relaxation and medication efficacy in self-management of rheumatoid arthritis patients

陆军军医大学学报
Objective To explore the networked association among the dimensions of self-efficacy in patients with rheumatoid arthritis (RA) and to identify core efficacy and bridge efficacy, and provide a basis for formulating precise nursing intervention ...
DENG Yao , ZHANG Sha, XIANG Xiaorun
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

Understanding perceived stigma and depression symptoms in maintenance hemodialysis patients: a network perspective

Frontiers in Psychology
ObjectivesPatients undergoing maintenance hemodialysis (MHD) experience stigma due to their reliance on machines and changes in appearance, contributing to negative psychological outcomes.
Yurong Li, Yaoyao Yang, Yaoyao Yang, Shiman Liang, Guanghui Cao, Jinjin Yang   +5 more
doaj   +1 more source

Assessing relinquishment of positivity as a central symptom bridging anxiety and depression

Journal of Affective Disorders
Anxiety and depression are often comorbid and chronic disorders. Previous research indicates that positivity relinquishment is a moderator of anxiety and depression, such that only anxious individuals who endorsed relinquishing positivity were also depressed.
Camryn Calafiore, Amanda C. Collins, Gregory Bartoszek, E. Samuel Winer   +3 more
openaire   +3 more sources

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

The Politics of Bridge Building: The Long Wait for the Tees (Newport) Bridge [PDF]

, 2011
The Tees (Newport) Bridge officially opened in February 1934 to much fanfare and public celebration, the event receiving extensive local, regional and national media attention.
Warwick, Tosh
core   +3 more sources

The relationship between anxiety and obsessive-compulsive symptoms in psychiatric inpatients with anxiety disorders via network analysis

Guangxi Yike Daxue xuebao
Objective To investigate the interrelationships between individual symptoms of anxiety and obsessive-compulsive symptoms in patients with anxiety disorders, and to analyze the interactions between these symptom clusters.
Shujin Huang, Weiwei Lan, Lan Lan, Yan Song, Bing Lu, Shibin Wu, Li Su, Zukang Gong   +7 more
doaj   +1 more source

Bridge roughness index as an indicator of bridge dynamic amplification [PDF]

, 2006
The concept of a road roughness index for bridge dynamics is developed. The International Roughness Index (IRI) is shown to be very poorly correlated with bridge dynamic amplification as it takes no account of the location of individual road surface ...
O'Brien, Eugene J., González, Arturo, Li, Yingyan   +2 more
core   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source