Results 51 to 60 of about 2,121,605 (282)

Unveiling age-differentiated pathways: spiritual well-being links to quality of life in breast cancer survivors through network analysis

Frontiers in Public Health
BackgroundEnhancing the quality of life (QoL) of breast cancer survivors is a key public health priority. Spiritual well-being (SpWB) is recognized as a correlate, but its systemic role in connecting different life domains and how this varies by age ...
Cheng Yang, Cheng Yang, Cheng Yang, Qin Zeng, Qin Zeng, Jiawei Li, Jiawei Li   +6 more
doaj   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

Individual Wellbeing and Bridge: An Empirical Analysis [PDF]

, 2017
There is a growing interest in the Sociology of bridge. This research is part of a wider examination of bridge from a sociological and medical perspective, and is conducted with the intention of providing some of the groundwork for a larger study of the ...
McDonnell, Diarmuid, Small, Caroline, Punch, Samantha   +2 more
core  

Understanding Further the Phenotypic Spectrum of Central Nervous System Inflammatory Demyelinating Disorders Using Unsupervised Clustering

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Central nervous system (CNS) inflammatory demyelinating syndromes, including multiple sclerosis (MS), aquaporin‐4 antibody–positive neuromyelitis optica spectrum disorder (AQP4 + NMOSD), and myelin oligodendrocyte glycoprotein (MOG) antibody–associated disease (MOGAD), occasionally overlap.
Bade Gulec, Elif Everest, Melih Tutuncu, Ugur Bilge, Sabahattin Saip, Ugur Uygunoglu, Aksel Siva   +6 more
wiley   +1 more source

Blunted P300 Prospectively Bridges Cognitive Reappraisal and Depressive Symptoms

Psychophysiology
ABSTRACT Cognitive reappraisal is a crucial modulator of depression. Scant research has examined how the usage of cognitive reappraisal is prospectively linked with depressive symptoms through its modulation effect on P300. Moreover, there is limited knowledge about how the social‐environmental context, such as stressful societal ...
Kehan Li, Kyle Nash, Yao Zheng
openaire   +3 more sources

Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito, Kamal Benguerba, Ken Tsuchida, Kazushige Yazawa, Isao Tsumiyama, Hiromitsu Kayama, Sandra P. Reyna, Farid Khan, Richard S. Finkel   +8 more
wiley   +1 more source

Exploring Bridge Symptoms between Somatic Symptom Clusters and Anxiety and Depression Symptoms among Patients Recovering from Stroke: A Network Analysis

Heart and Mind
Background: Bridge symptoms connect different symptom clusters in a network and may serve as precise intervention targets. This study aimed to explore the bridge symptoms between somatic symptoms and anxiety and depressive symptoms among patients ...
Yao Huang, Teng Li, Qian Yu, Suyao Li
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

105 years with the interstate bridge

, 2022
The Interstate Bridge opened on February 14, 1917 amid much fanfare. It cost travelers -- both vehicles and horses! -- five cents to cross the bridge. There were two lanes of traffic, one in each direction, as well as a streetcar.

core  

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source