Results 141 to 150 of about 545,733 (311)

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Effects of teriparatide in Chinese and Caucasian women with osteoporosis: bridging study on efficacy

Clinical Interventions in Aging, 2019
Zhongjian Xie,1 Yun Chen,2 Sirel Gurbuz,3 Bin Zhang,2 Yujie Li,2 Fan Bai,2 Yu Chen2 1Department of Metabolism and Endocrinology, Hunan Provincial Key Laboratory of Metabolic Bone Diseases and National Clinical Research Center for Metabolic Diseases, The
Xie Z, Chen Y, Gurbuz S, Zhang B, Li Y, Bai F, Chen Y   +6 more
doaj  

Carnitine dysregulation in diabetic kidney disease: from pathogenic mechanism to precision biomarker

Journal of Translational Medicine
Carnitine is essential for mitochondrial fatty acid β-oxidation and redox homeostasis, and mounting evidence shows that carnitine metabolism is profoundly perturbed in diabetic kidney disease (DKD).
Yuanhua Dai, Shiru Duan, Yuxi Li, Jin Rong, Hanfei Li, Weiping Su, Xiaoya Wu, Xiaoyu Peng, Huiming Qi, Shunmei Liu, Tingting Zhao   +10 more
doaj   +1 more source

Supporting English language learning by bridging from childrens' first languages in Papua New Guinea: An analysis of Grade 3 teachers' conceptions and practices [PDF]

, 2010
This is a descriptive study that was conducted with selected Grade 3 teachers in the East New Britain Province of Papua New Guinea. Grade 3 teachers implement bridging in bilingual education using the children's local vernacular language and/or Tok Pisin
August, Matilda
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Bridging compliance and responsibility

BRIDGING COMPLIANCE AND RESPONSIBILITY Bridging compliance and responsibility ...
Kummer, Sebastian, Sigala, Ioanna Falagara, Wang, Melissa, Wirtschaftsuniversität Wien   +3 more
core   +1 more source

XSEDE Campus Bridging Use Cases v3.0

, 2018
The XSEDE Campus Bridging Use Cases describe how campus information technology (IT) administrators and campus-based research projects treat XSEDE's resources as extensions of their campus environments, offer services at their campuses to others in the ...

core  

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source