Results 81 to 90 of about 1,040 (235)

Loss of PI3Kδ Activity Drives Autoimmune Colitis by Impairing Extrathymic Treg Differentiation

European Journal of Immunology, Volume 55, Issue 10, October 2025.
Mice with inactivated PI3Kδ develop colitis, reminiscent of immune‐related adverse effects observed in human patients treated with PI3Kδ inhibitors. We demonstrate that loss of PI3Kδ activity abrogates the Helios− peripherally induced Treg (pTreg) population in the mouse colon, resulting in inflammation and tissue damage that Helios+ thymic Tregs fail ...
Ee Lyn Lim, Yamin Qian, Fuminori Sugihara, Atsushi Tanaka, Shimon Sakaguchi   +4 more
wiley   +1 more source

Morphometric analysis of brightest cluster galaxies

Monthly Notices of the Royal Astronomical Society, 2020
ABSTRACT We study the build-up of the stellar mass of brightest cluster galaxies (BCGs) at z < 0.1 as a function of their morphological type. Morphometric parameters for 1216 BCGs were obtained from the SDSS DR12 r-band images with the code morfometryka.
J Cougo, S B Rembold, F Ferrari, A L P Kaipper   +3 more
openaire   +1 more source

The Emergence of a Brightest Cluster Galaxy in a Protocluster Core at z = 2.24

The Astrophysical Journal
We report the detection of a pair of massive quiescent galaxies likely in the process of merging at the center of the spectroscopically confirmed, extremely massive protocluster BOSS1244 at z = 2.24 ± 0.02.
Dong Dong Shi, Xin Wang, Xian Zhong Zheng, Zheng Cai, Xiaohui Fan, Fuyan Bian, Harry I. Teplitz   +6 more
doaj   +1 more source

A Chromosome Inversion Creates a Supergene for Sex and Colour in Lake Malawi Cichlids

Molecular Ecology, Volume 34, Issue 20, October 2025.
ABSTRACT Cichlid fishes have the highest rates of evolutionary turnover of sex chromosomes among vertebrates. Many large structural polymorphisms in the radiation of cichlids in Lake Malawi are associated with sex chromosomes and may also carry adaptive variation.
Kristen A. Behrens, Soumya Jailwala, Frances E. Clark, Anne C. Meyer, Nikesh M. Kumar, Adrianus F. Konings, Reade B. Roberts, Matthew A. Conte, Jeffrey T. Streelman, Patrick T. McGrath, Thomas D. Kocher   +10 more
wiley   +1 more source

Brightest cluster galaxies and the intracluster light

In this chapter, we delve into the formation and primary characteristics of two significant components within galaxy clusters: the brightest cluster galaxies (BCGs) and the intracluster light (ICL). Drawing upon recent and pertinent studies in the field, we explore the mechanisms driving their growth from high redshift to the present day, i.e., mergers
Contini, Emanuele, Yi, Sukyoung K., Jeon, Seyoung   +2 more
openaire   +2 more sources

Reassessing the Relationship Between Meteor Radio Afterglows and Optical Persistent Trains

Journal of Geophysical Research: Space Physics, Volume 130, Issue 9, September 2025.
Abstract Meteor radio afterglows (MRAs) and optical persistent trains (PTs) are two types of long‐lived phenomena which are occasionally observed following the occurrence of a meteor. Both phenomena are thought to be produced by intrinsic emission mechanisms; PTs have been associated with chemiluminescent reactions between meteoric metals and ...
L. E. Cordonnier, K. S. Obenberger, G. B. Taylor, J. M. Holmes, J. Dowell, D. Vida   +5 more
wiley   +1 more source

Spectral Energy Distribution Fitting of Globular Clusters in NGC 4874: Masses and Metallicities

The Astrophysical Journal
In most nearby galaxies, photometry of the integrated light of their globular clusters (GCs) has been obtained in only two filters, yielding just a single color index.
Kate Hartman, William E. Harris, Jinoo Kim   +2 more
doaj   +1 more source

Spectroscopic and X-ray Modeling of the Strong Lensing Galaxy Cluster MACS J0138.0-2155

The Open Journal of Astrophysics
We model the total mass and galactic substructure in the strong lensing galaxy cluster MACS J0138.0-2155 using a combination of Chandra X-ray data, Multi-Unit Spectroscopic Explorer (MUSE) spectroscopy, and Hubble Space Telescope imaging.
Abigail Flowers, Jackson H. O'Donnell, Tesla E. Jeltema, Vernon Wetzell, M. Grant Roberts   +4 more
doaj   +1 more source

Coevolution of Brightest Cluster Galaxies and Their Host Clusters in IllustrisTNG

, 2022
Jubee Sohn, Margaret J. Geller, Mark Vogelsberger, Ivana Damjanov   +3 more
openalex   +1 more source

Brightest cluster galaxies as standard candles

The Astrophysical Journal, 1995
We investigate the use of brightest cluster galaxies (BCGs) as standard candles for measuring galaxy peculiar velocities on large scales. We have obtained precise large-format CCD surface photometry and redshifts for an all-sky, volume-limited (z less than or = 0.05) sample of 199 BCG. We reinvestigate the Hoessel (1980) relationship between the metric
Marc Postman, Tod R. Lauer
openaire   +1 more source