Results 51 to 60 of about 29,250 (249)

Discovery, Observational Data and the Orbit of the Amor Group Asteroid 2010 BT3

Open Astronomy, 2012
A project devoted to astrometric and photometric observations of asteroids at the Molėtai Observatory is described. One of its most important results is the discovery of the asteroid 2010 BT3 belonging to the Amor group of the near-Earth objects.
Černis K., Zdanavičius J., Wlodarczyk I., Stonkutė E.   +3 more
doaj   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Ultrabright LaB6 nanoneedle field emission electron source with low vacuum compatibility

Communications Materials
An electron source with high performance and low vacuum compatibility is urgently in demand for the electron-beam instruments. However, there exists compromise between high brightness, small energy spread, and low vacuum for the commercial electron ...
Mingkai Gou, Shuai Tang, Kai Huang, Haokun Guan, Runze Zhan, Chaolun Liang, Chengcheng Chen, Yan Shen, Shaozhi Deng   +8 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Space debris contributions to night sky brightness

Astronomy & Astrophysics
Aims. We quantify the uncertainty in space debris contributions to night sky brightness by comparing predictions from two major debris environment models and assessing the resulting signal-to-noise degradation for ground-based astronomical observations ...
Wallner S., Kocifaj M., Silha J.
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Simulated Impact on LSST Data of Starlink V1.5 and V2 Satellites

The Astronomical Journal
The new Starlink V2 satellites incorporate improvements to the chassis brightness through dielectric mirrors, off-pointing solar arrays, and blackened exposed components. For the general case in which the reflectivities are initially unknown, we simulate
Phanindra Kandula, J. Anthony Tyson, Jacob Askari, Forrest Fankhauser   +3 more
doaj   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

An effective method for the detection of trace species demonstrated using the MetOp Infrared Atmospheric Sounding Interferometer [PDF]

Atmospheric Measurement Techniques, 2011
Fast and reliable methods for the detection of atmospheric trace species are needed for near-real-time applications including volcanic hazard avoidance.
J. C. Walker, A. Dudhia, E. Carboni
doaj   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source