Results 61 to 70 of about 3,908,495 (300)
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
On High Brightness Temperature of Pulsar Giant Pulses [PDF]
A wide range of events observed at the giant pulses (high energy density, observed localization of giant pulses (GPs) relative to the average pulse, fine structure of GPs with duration up to some nanoseconds, observed circular polarization of GPs, correlation between the GP phase and the phase of the hard pulsar emission X-ray and gamma) can be ...
openaire +2 more sources
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Lunar heat flow from the observation of Chinese Chang’E 2 and LRO diviner radiometers
Lunar heat flow within 75°N to 65°S and 60°W to 100°E regions is retrieved from microwave brightness temperature observed by Chang’E-2 (CE-2) Lunar Microwave Radiometers and infrared brightness temperature observed by Lunar Reconnaissance Orbiter (LRO ...
Dan Zhang, Cui Li
doaj +1 more source
SMOS brightness temperature assimilation into the Community Land Model [PDF]
SMOS (Soil Moisture and Ocean Salinity mission) brightness temperatures at a single incident angle are assimilated into the Community Land Model (CLM) across Australia to improve soil moisture simulations. Therefore, the data assimilation system DasPy
D. Rains +5 more
doaj +1 more source
A Relationship between the Brightness Temperatures for Type III Bursts [PDF]
(Solar Phys.). The widely accepted emission mechanisms for type III bursts involve at least two stages. The first stage is the generation of Langmuir waves by the inferred stream of electrons. Emission at the fundamental frequency arises when these waves are scattered by thermal ions.
openaire +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source
Limiting Brightness Temperature for Synchrotron Sources [PDF]
AbstractThe maximum brightness temperature limit for synchrotron sources derived from inverse Compton catastrophe is usually taken to be 1012 K. Readhead has argued in 1994 that the equipartition brightness temperature may be a better estimate for Tb,lim. It provides a value of 5 × 1010 K.
A. Lähteenmäki, E. Valtaoja
openaire +1 more source
Directed evolution of enzymes at the crossroads of tradition and innovation
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova +2 more
wiley +1 more source

