Results 41 to 50 of about 1,354 (149)

Interventions to Prevent Postinflammatory Hyperpigmentation After Laser and Energy‐Based Device Treatments: A Systematic Review and Network Meta‐Analysis

Lasers in Surgery and Medicine, Volume 58, Issue 3, Page 157-168, March 2026.
ABSTRACT Background Postinflammatory hyperpigmentation (PIH) is the most common adverse effect following laser treatments, yet the relative efficacy of proposed prophylactic measures remains uncertain. Objectives To compare the effectiveness of available interventions for preventing laser‐induced PIH in randomized controlled trials (RCTs).
Supisara Wongdama, Sasitorn Yenyuwadee, Jayne Bernadeth Li, Surasak Saokaew, Sukrit Kanchanasurakit, Woraphong Manuskiatti   +5 more
wiley   +1 more source

Reflectance Confocal Microscopy of Rosacea: Disease Features and Microscopic Changes During Vitamin A and Vitamin E Supplementation Therapy

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Rosacea is a chronic inflammatory skin disorder affecting the central face, often presenting with erythema, papules, pustules, and telangiectasia. Its pathogenesis involves dysregulation of the innate immune system, increased antimicrobial peptide (cathelicidin) activity, and microbial colonization, particularly by Demodex folliculorum and ...
Manfredini M., Milandri M., Barbieri M., Marchio T., Ciardo S., Longo C., Suraiya Saleem   +6 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source

Nanovesicular Formulation of Brimonidine Tartrate for the Management of Glaucoma: In Vitro and In Vivo Evaluation [PDF]

AAPS PharmSciTech, 2011
In this study, nanovesicles were developed for brimonidine tartrate by film hydration technique and dispersed in viscous carbopol solution for ocular delivery. Scanning electron microscopy revealed spherical shape of the vesicles. As high as 32.27% drug entrapment efficiency was achieved depending upon the surfactant/cholesterol molar ratio (7:4 to 7:8)
Sabyasachi, Maiti, Sayon, Paul, Ranjit, Mondol, Somasree, Ray, Biswanath, Sa   +4 more
openaire   +2 more sources

Evaluation of the effect of an extract of Sphingomonas xenophaga present in a Thermal Spring Water in the management of sensitive skin associated with cutaneous vascular disorder

International Journal of Cosmetic Science, Volume 47, Issue 6, Page 1017-1025, December 2025.
Inhibition of the kallikrein‐kinin system is a potential approach to the dermocosmetic treatment of skin disorders associated with redness. We showed that a cream formulation with a Sphingomonas ferment extract inhibiting this system was effective in improving vascular disorder after repeated application in female volunteers with sensitive and reactive
Pascal Hilaire, Carine Ballihaut, Celine Cornillon, Mark Donovan, Cosima Dufour‐Schroif, Delphine Kerob, Jean‐Jacques Schoonjans, Anna Veriato   +7 more
wiley   +1 more source

Effects of intracameral tissue plasminogen activator injection on posterior capsular opacification, fibrin formation, and intraocular pressure in dogs after phacoemulsification

Veterinary Ophthalmology, Volume 28, Issue 6, Page 917-925, November 2025.
Abstract Objective To evaluate whether intracameral tissue plasminogen activator (tPA) injection is effective in regulating posterior capsular opacification (PCO), fibrin formation and intraocular pressure (IOP) after cataract surgery. Animal Studied Prospective study involving 30 eyes of 21 dogs that underwent phacoemulsification.
Kyulee Kim, Young‐Sun Kang, Joon Young Kim   +2 more
wiley   +1 more source

Post‐Trabeculectomy Refractory Shallow Anterior Chamber: A Case Highlighting Overlooked Patient Behavior

Clinical Case Reports, Volume 13, Issue 10, October 2025.
ABSTRACT A shallow anterior chamber (AC) after glaucoma filtration surgery is a common early postoperative complication that can be vision‐threatening. So, early recognition of the causative factors and prompt management are necessary to avoid such devastating complications after surgery.
Md. Iftekher Iqbal, Fariah Osman
wiley   +1 more source

Novel Uses of Brimonidine

Delhi Journal of Ophthalmology
Brimonidine tartrate is a third-generation, highly selective alpha 2 agonist currently available in various formulations and doses to treat ophthalmological conditions. The aim of this article was to review pharmacokinetics, mechanisms, side effects, and
Hikkalagutti. S. Kruthika, Chauhan Tulika, Patyal Sagarika, Bhardwaj Kanika, Dabas Garvita   +4 more
doaj   +1 more source

Visual field testing and glaucoma drug prescribing patterns in Australia

Ophthalmic and Physiological Optics, Volume 45, Issue 5, Page 1228-1237, July 2025.
Abstract Purpose To examine glaucoma practice patterns in Australia, focusing on visual field test uptake and antiglaucoma drug prescribing by optometrists and ophthalmologists. Design A serial cross‐sectional study was conducted to describe visual field testing charges and compare them to changes in comprehensive eye examination charges, as well as to
Catherine L. Jan, Algis Vingrys, Randall S. Stafford, Mengtian Kang, Xianwen Shang, Wenyi Hu, Jiahao Liu, Sanil Joseph, Mingguang He   +8 more
wiley   +1 more source

Nummular keratitis: A rare manifestation of brimonidine allergy

Oman Journal of Ophthalmology
A 32-year-old male, with juvenile open-angle glaucoma on chronic antiglaucoma therapy and recently introduced brimonidine eye drops to the treatment regimen, developed bilateral follicular conjunctivitis with subepithelial infiltrates (SEIs) initially ...
Maitha Al Asmi, Aisha Al Busaidi
doaj   +1 more source