Results 41 to 50 of about 12,798 (141)

Dual‐Responsive Chitosan‐Grafted PNIPAAm Hydrogel Eye Drop Incorporating Insulin‐Imprinted Microgels for Dry Eye Syndrome Treatment

Macromolecular Bioscience, Volume 26, Issue 6, June 2026.
ABSTRACT Dry eye syndrome (DES) happens as a result of inadequate tear secretion or excessive evaporation, which leads to ocular surface irritation and damage. A major therapeutic challenge is maintaining effective drug concentrations, as topical formulations are rapidly cleared by blinking and tear turnover.
Masoumeh Alsadat Hosseini, Reihaneh Khademi, Mahshid Shokri, Reza Ghiasi, Ali Doostmohammadi, Mahshid Kharaziha, Sahar Salehi   +6 more
wiley   +1 more source

Innovative Drug Delivery Systems for the Treatment of Glaucoma

MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.
This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu, Junzhi Li, Zhenlin Chen, Jinyu Zhang, Siqi Feng, Jiaying Huang, Yawen Chu, Xue Zhou, Wei Wang, Shangsi Chen   +9 more
wiley   +1 more source

Is Brimonidine Tartrate Gel .5% Effective in Reducing Facial Erythema of Rosacea? [PDF]

, 2016
OBJECTIVE: The objective of this selective Evidence Based Medicine (EBM) review is to determine whether or not “Is Brimonidine Tartrate gel 0.5% effective in reducing facial erythema of Rosacea?” STUDY DESIGN: Review of two randomized controlled trials ...
Aggarwal, Meeta
core   +1 more source

Congenital aniridia: European COST action ANIRIDIA‐NET guidelines for diagnosis, management and care

Acta Ophthalmologica, Volume 104, Issue 3, Page 267-279, May 2026.
Abstract Congenital aniridia is a rare ocular disorder affecting the majority of eye structures and can be associated with systemic manifestations. The main visible phenotypic characteristic is the partial or complete absence of the iris; however, foveal hypoplasia is a more frequent and reliable clinical sign. Other ocular comorbidities are associated
Davide Romano, Vito Romano, Alejandra Daruich, Giulio Ferrari, Matthieu Robert, Francesco Semeraro, Neil Lagali, Dominique Bremond‐Gignac, the ANIRIDIA‐NET Clinical Guidelines Working Group, Miriam Barbany, Claus Cursiefen, Stefano Ferrari, Francisco Figueiredo, Christina Grupcheva, Jesper Hjortdal, Elke Kreps, Erlend Landsend, Laura Mauring, Hilde Pedersen, Nora Szentmáry, Bogumil Wowra, the Aniridia‐Europa and Geniris Working Group, Sophie Valleix, Juan Álvarez de Toledo, James Lauderdale, Tor Paaske Utheim, Paolo Rama   +26 more
wiley   +1 more source

Efficacy and Safety of a Dual‐Wavelength 589/1319 nm Laser for the Treatment of Acne Erythema: A Split‐Face Randomized Controlled Trial

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background The 589/1319 nm solid‐state dual‐wavelength (SSDW) laser, which targets cutaneous vasculature, may be an effective treatment for acne erythema (AE). Objectives To compare the efficacy and safety of the 589/1319 nm SSDW laser with topical soothing Aloe vera (AV) gel for the treatment of AE.
Suphagan Boonpethkaew, Pimsiri Anansiripun, Warittha Maitrisathit, Yanisa Ratanapokasatit, Sonphet Chirasuthat, Panrudee Wechsuruk, Penpun Wattanakrai   +6 more
wiley   +1 more source

The use of Topical Brimonidine in Dermatology [PDF]

Minia Journal of Medical Research, 2019
Introduction: Brimonidine tartrate is a lipid soluble alpha 2 adrenergic highly selective receptor agonist with potent vasoconstrictor activity that had been approved for management of open angle glaucoma, it is also currently indicated for the topical ...
Samah Abdel hameed, Walid Abd El-Naeim, Moetaz El-Domyati   +2 more
doaj   +1 more source

An Attempt to Establish the Consensus Regarding the Diagnosis, Classification, and Treatment of Rosacea in Japan Using a Modified Delphi Method: The Japan Rosacea Consensus

The Journal of Dermatology, Volume 53, Issue 4, Page 605-618, April 2026.
ABSTRACT In Japan, rosacea has attracted increasing interest. However, because rosacea had been thought to be relatively rare in Japan, the perception of this disease varies among dermatologists. To address these challenges, this study developed a consensus regarding the diagnosis, classification, and treatment of rosacea using a modified Delphi method
Kenshi Yamasaki, Nobukazu Hayashi, Hiroaki Hayashi, Yasuko Fukuya, Yuki Horiuchi, Miwa Kobayashi, Yoshimasa Nobeyama, Jun Omatsu, Kanako Tsunoda, Yoshiki Miyachi   +9 more
wiley   +1 more source

Interventions to Prevent Postinflammatory Hyperpigmentation After Laser and Energy‐Based Device Treatments: A Systematic Review and Network Meta‐Analysis

Lasers in Surgery and Medicine, Volume 58, Issue 3, Page 157-168, March 2026.
ABSTRACT Background Postinflammatory hyperpigmentation (PIH) is the most common adverse effect following laser treatments, yet the relative efficacy of proposed prophylactic measures remains uncertain. Objectives To compare the effectiveness of available interventions for preventing laser‐induced PIH in randomized controlled trials (RCTs).
Supisara Wongdama, Sasitorn Yenyuwadee, Jayne Bernadeth Li, Surasak Saokaew, Sukrit Kanchanasurakit, Woraphong Manuskiatti   +5 more
wiley   +1 more source

Reflectance Confocal Microscopy of Rosacea: Disease Features and Microscopic Changes During Vitamin A and Vitamin E Supplementation Therapy

Dermatologic Therapy, Volume 2026, Issue 1, 2026.
Background Rosacea is a chronic inflammatory skin disorder affecting the central face, often presenting with erythema, papules, pustules, and telangiectasia. Its pathogenesis involves dysregulation of the innate immune system, increased antimicrobial peptide (cathelicidin) activity, and microbial colonization, particularly by Demodex folliculorum and ...
Manfredini M., Milandri M., Barbieri M., Marchio T., Ciardo S., Longo C., Suraiya Saleem   +6 more
wiley   +1 more source

Evolving Real‐World Data and Evidence Use for New Drugs and Regenerative Medical Products Approvals in Japan—An Analysis of the 6‐Year Trend

Clinical Pharmacology &Therapeutics, Volume 118, Issue 6, Page 1405-1421, December 2025.
Several regulatory initiatives have been made to clarify the acceptability and requirements of real‐world data and real‐world evidence (RWD/E) for the benefit/risk assessment of new medical products in Japan. The objectives of this review were to characterize the use of RWD/E in regulatory applications of new medical products and to describe the ...
Suguru Okami, Kako Shimotsumagari, Yasunari Sadatsuki   +2 more
wiley   +1 more source