Results 21 to 30 of about 2,190 (195)
Brimonidine tartrate-induced delayed hypersensitivity reaction
TNOA Journal of Ophthalmic Science and Research, 2020 Chitaranjan Mishra +1 more
doaj +2 more sources
Advanced ScienceEfficient topical drug delivery remains a significant challenge in glaucoma management. Although nanoparticle formulations offer considerable promise, their complex preparation processes, co‐delivery issues, and batch consistency have hindered their ...
Da Huang +8 more
doaj +2 more sources
Drug-loaded chitosan film prepared via facile solution casting and air-drying of plain water-based chitosan solution for ocular drug delivery [PDF]
Bioactive Materials, 2020 Chitosan is a nature-based polymer with low toxicity, excellent biocompatibility and biodegradability. However, the intractable solubility of chitosan in water and most conventional solvents hampers its biomedical applications.
Boxuan Li, Juan Wang, Qin Gui, Hu Yang
doaj +3 more sources
Development of Brimonidine-Loaded Ethosomes for Glaucoma: Investigation of Intraocular Pressure-Lowering Potential In Vivo [PDF]
PharmaceuticsBackground/Objectives: Brimonidine tartrate (BRT), a selective α2-adrenergic receptor agonist, is commonly used in the treatment of glaucoma. However, conventional eye drop formulations suffer from poor ocular bioavailability and rapid elimination.
Samet Özdemir +7 more
doaj +2 more sources
Does topical brimonidine tartrate help NAION? [PDF]
British Journal of Ophthalmology, 2003 There is no proved treatment for non-arteritic anterior ischaemic optic neuropathy (NAION). Topical brimonidine tartrate has been reported to have a neuroprotective benefit for retinal ganglion cells following experimental elevation of intraocular pressure and optic nerve injury in the rat, which is blocked with coadministration of the α-2 antagonist ...
H E, Fazzone +2 more
openaire +2 more sources
Ophthalmology and Therapy, 2020 Introduction This study was aimed to compare ocular tissue distribution and systemic exposure of brimonidine and timolol after single topical administration to rabbits of fixed-combination ophthalmic solution of 0.1% brimonidine tartrate and 0.5% timolol
Gen Suzuki +5 more
doaj +1 more source
Ophthalmology and Therapy, 2023 Introduction The factors related to the ocular penetration of drugs after the administration of eye drops in humans have not been examined in detail. Therefore, this study assessed the influence of patient factors on the intraocular penetration of eye ...
Eriko Kunikane +3 more
doaj +1 more source
Effect of Brimonidine Tartrate on Ocular Hemodynamic Measurements [PDF]
Archives of Ophthalmology, 1998 To study the effect of a selective alpha 2-adrenoreceptor agonist, brimonidine tartrate, on ocular hemodynamics.Eighteen patients with ocular hypertension were enrolled in a prospective, randomized, double-masked study in which 0.2% brimonidine tartrate, administered twice daily, was compared with its vehicle in a crossover fashion.
Y, Lachkar, C, Migdal, S, Dhanjil
openaire +2 more sources
Multidisciplinary Consideration of Potential Pathophysiologic Mechanisms of Paradoxical Erythema with Topical Brimonidine Therapy. [PDF]
, 2016 Rosacea is a chronic inflammatory disease with transient and non-transient redness as key characteristics. Brimonidine is a selective α2-adrenergic receptor (AR) agonist approved for persistent facial erythema of rosacea based on significant efficacy and
Detmar, Michael +6 more
core +2 more sources
Therapeutic approaches with intravitreal injections in geographic atrophy secondary to age-related macular degeneration: current drugs and potential molecules [PDF]
, 2019 The present review focuses on recent clinical trials that analyze the efficacy of intravitreal therapeutic agents for the treatment of dry age-related macular degeneration (AMD), such as neuroprotective drugs, and complement inhibitors, also called ...
Cerini, Alberto +5 more
core +1 more source