Results 11 to 20 of about 2,190 (195)

Preparation and Characterization of Ion-Sensitive Brimonidine Tartrate In Situ Gel for Ocular Delivery [PDF]

Pharmaceuticals, 2023
Brimonidine tartrate (BRT) is a highly selective α2 adrenergic receptor agonist as treatment for patients with open angle glaucoma and high intraocular pressure.
Haonan Xu, Ye Liu, Lu Jin, Xu Chen, Xinghao Chen, Qiao Wang, Zhan Tang   +6 more
doaj   +4 more sources

Augmented in vitro and in vivo Profiles of Brimonidine Tartrate Using Gelatinized-Core Liposomes [PDF]

International Journal of Nanomedicine, 2022
Engy A Abdel Azim,1 Seham A Elkheshen,2,* Rania M Hathout,3,* Marwa A Fouly,4 Nada M El Hoffy1 1Department of Pharmaceutics and Pharmaceutical Technology, Faculty of Pharmacy, Future University in Egypt, New Cairo, Cairo, 11835, Egypt ...
Abdel Azim EA, Elkheshen SA, Hathout RM, Fouly MA, El Hoffy NM   +4 more
doaj   +2 more sources

A validated stability-indicating HPLC method for determination of brimonidine tartrate in BRI/PHEMA drug delivery systems [PDF]

Chemistry Central Journal, 2017
Background A simple, rapid and accurate stability-indicating reverse phase high performance liquid chromatography (RP-HPLC) was developed and validated for the determination of brimonidine tartrate in brimonidine tartrate/poly(2-hydroxyethyl methacrylate)
Jianguo Sun, Xiuwen Zhang, Taomin Huang
doaj   +2 more sources

A stability-indicating RP-HPLC method for the simultaneous quantification of brimonidine tartrate and timolol maleate in bulk drug substances and pharmaceutical dosage forms [PDF]

Scientific Reports
A robust, rapid, and reproducible reversed-phase high-performance liquid chromatography (RP-HPLC) method was developed and validated for the simultaneous quantification of Brimonidine Tartrate and Timolol Maleate (Combigan) in ophthalmic dosage forms ...
Aktham Mestareehi
doaj   +2 more sources

Use of brimonidine tartrate to resolve telangiectatic matting: case report. [PDF]

J Vasc Bras, 2020
Sclerotherapy is currently the treatment of choice for telangiectasias and reticular veins, with grade 1A recommendation in the European Guideline for sclerotherapy. The most common side effects of this procedure are hyperpigmentation and telangiectatic matting, the second of which provokes great concern because of the esthetic damage and the ...
de Mello BAS, Beiriz YR, Bonatto AC, Maciel GSB, de Almeida LR, Corassa JM.   +5 more
europepmc   +3 more sources

Brimonidine tartrate 0.15% drops to reduce low post-LASIK residual myopia: A retrospective study. [PDF]

PLoS ONE
PurposeResidual myopia following Laser-assisted in situ keratomileusis (LASIK) surgery poses a significant concern, with existing literature extensively detailing the use of timolol for treatment.
Nir Gomel, Asaf Achiron, Nadav Shemesh, Elad Eilon, Tal Yahalomi, Dana Barequet, Nadav Levinger, Dafi Porat, Shmuel Levinger, Ami Hirsch, Nir Sorkin, Eliya Levinger   +11 more
doaj   +3 more sources

A Multicenter Randomized Double-Masked Study Comparing Preservative-free Brimonidine Tartrate Ophthalmic Solution 0.025% with LUMIFY® 0.025% for Ocular Redness in Adults [PDF]

Ophthalmology and Therapy
Introduction Ocular redness is common, can affect quality of life, and can be relieved by short-term use of topical adrenergic receptor (AR) agonists. Brimonidine tartrate ophthalmic solution 0.025% (LUMIFY® 0.025%) is the first α2-AR-selective agonist ...
Melissa Toyos, Melinda DiVito, Elisabeth M. Messmer, Selina McGee, Jared Peterson, Assem Patel, Guruprasad Pattar, David G. Evans, Patrick M. Vollmer, Gina Wesley   +9 more
doaj   +2 more sources

Fabrication of Anti-glaucoma Nanofibers as Controlled-Release Inserts for Ophthalmic Delivery of Brimonidine Tartrate: In Vivo Evaluation in Caprine Eye [PDF]

Advanced Pharmaceutical Bulletin
Purpose: Chronic ailments usually decrease the quality of life due to the requirement for repetitive administration of drugs. Glaucoma is a chronic eye disease occurred because of increased intraocular pressure (IOP).
Fariba Shaikhi Shoushtari, Mohammadshakib Naghshbandy, Leila Rezaei, Saba Mehrandish, Shahla Mirzaeei   +4 more
doaj   +2 more sources

Modification of contact lenses via metal‐organic frameworks for glaucoma treatment

Aggregate
The prevention of blindness from glaucoma requires multiple treatments to lower intraocular pressure. Here, human contact lenses are modified with highly porous metal‐organic frameworks with sustained release of brimonidine for prolonged glaucoma ...
Alexey V. Yaremenko, Roman O. Melikov, Nadezhda A. Pechnikova, Iaroslav B. Belyaev, Alina Ringaci, Tamara V. Yaremenko, Aziz B. Mirkasymov, Alexandr A. Tamgin, Vladislav I. Rodionov, Sofya M. Dolotova, Grigory A. Plisko, Evgeny D. Semivelichenko, Anna S. Rogova, Albert R. Muslimov, Arina S. Ivkina, Dmitry Yu. Ivkin, Valery P. Erichev, Sergey M. Deyev, Sergey E. Avetisov, Yongjiang Li, Hai‐Jun Liu, Ivan V. Zelepukin   +21 more
doaj   +2 more sources

Proniosomal gel-derived niosomes: an approach to sustain and improve the ocular delivery of brimonidine tartrate; formulation, in-vitro characterization, and in-vivo pharmacodynamic study [PDF]

Drug Delivery, 2019
Brimonidine tartrate (BRT) is a hydrophilic α2 adrenergic agonist used for the treatment of glaucoma. Glaucoma is an ocular disease affecting the anterior segment of the eye requiring lifetime treatment.
Alaa Emad Eldeeb, Salwa Salah, Mahmoud Ghorab   +2 more
doaj   +2 more sources