Results 141 to 150 of about 122,768 (319)

Targeting Replication Fork Processing Synergizes with PARP Inhibition to Potentiate Lethality in Homologous Recombination Proficient Ovarian Cancers

open access: yesAdvanced Science, EarlyView.
This study demonstrates that the resveratrol analogue, trans‐4,4′‐dihydroxystilbene (DHS), exhibits synergistic anti‐tumor activity with the PARP inhibitor talazoparib, inducing significant ovarian cancer cell death. The synergistic effect of this combination arises from the concurrent downregulation of homologous recombination factors and the ...
Ganesh Pai Bellare   +7 more
wiley   +1 more source

A simulation study of the impact of fracture networks on the co-production of geothermal energy and lithium [PDF]

open access: yesarXiv
Co-production of geothermal energy and lithium is an emerging opportunity with the potential to enhance the economic potential of geothermal operations. The economic reward of extracting lithium from geothermal brine is determined by how the lithium concentration evolves during brine production.
arxiv  

Enhancing Osteogenesis through Bio‐Inspired Recombinant Coral Protein Galaxin by Targeting Mitochondrial Metabolism and ATP Production

open access: yesAdvanced Science, EarlyView.
The study highlights the potential of recombinant galaxin (a coral protein) as a novel and effective biomaterial for bone regeneration. It binds to ATP synthase subunit β (ATP5B) in mouse pre‐osteoblasts, thereby causing increased ATP production and mitochondrial activity.
Fei Yu   +6 more
wiley   +1 more source

Mg‐doped α‐Ga2O3 Nanorods for the Construction of Photoelectrochemical‐Type Self‐Powered Solar Blind UV Photodetectors and Underwater Imaging Application

open access: yesAdvanced Science, EarlyView.
A low‐cost hydrothermal technique is employed to optimize the synthesis of Mg‐doped α‐Ga2O3 nanorod arrays. Compared to undoped α‐Ga2O3 photodetectors, the photocurrent response is increased by 435%, with a peak responsivity of 34.54 mA W−1. Furthermore, a 5 × 5 PEC‐SBPD array based on Mg‐doped α‐Ga2O3 nanorod arrays is constructed for underwater ...
Xin Zhou   +9 more
wiley   +1 more source

Anion Exchange Membrane Seawater Electrolysis at 1.0 A cm−2 With an Anode Catalyst Stable for 9000 H

open access: yesAdvanced Science, EarlyView.
The CAPist‐S1 catalyst containing dense interlayer structure is synthesized by one‐step autologous method. The dense NiFe LDH interlayer inhibits the Cl− ions penetration onto metal substrate, significantly improving the corrosion resistance. The obtained catalyst requires an overpotential of 220 mV at 1.0 A cm−2 and exhibits excellent durability over ...
Jian Du   +6 more
wiley   +1 more source

A Bias‐Tunable Multispectral Photodetector Based on a GaN/TexSe1‐x Homo‐Type Heterojunction with a Unidirectional Barrier

open access: yesAdvanced Science, EarlyView.
A bias‐tunable multispectral photodetector based on a TexSe1‐x/GaN homo‐type heterojunction with a unidirectional barrier is proposed. By modulating the bias polarity and magnitude, the device's spectral response range can be extended from UV to the SWIR region.
Weijie Liu   +14 more
wiley   +1 more source

OcuPair, a Novel Photo‐crosslinkable PAMAM Dendrimer‐Hyaluronic Acid Hydrogel Bandage/Bioadhesive for Corneal Injuries and Temporary Corneal Repair

open access: yesAdvanced Science, EarlyView.
A schematic diagram showing the OcuPair adhesive hydrogel formulation loaded into the final delivery device and applied over the full‐thickness corneal wound in an in vivo rabbit model of corneal injury followed by in situ crosslinking to form a transparent hydrogel bandage sealing the wound.
Siva P. Kambhampati   +6 more
wiley   +1 more source

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