Results 131 to 140 of about 594,538 (299)
Adenosine triphosphate as a modulator of protein interactions and stability
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley +1 more source
Operations off the east coast of Great Britain, 1914-1918.
O.U. 6354 (40).; "This monograph, which is based on the Naval Staff Monographs and the German Official History (Krieg Zur See, Nordsee, 6 Vols., I.D. Translations), deals with German operations off the East Coast of Great Britain during 1914-1918." -- p.
Great Britain. Admiralty. Naval Staff. Training and Staff Duties Division.
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GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain +11 more
wiley +1 more source
The public general acts of the United Kingdom of Great Britain and Ireland ...
Mode of access: Internet.Continued by: Great Britain. [Laws, etc.]. The Public general acts..
Great Britain.
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In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
Western Choiseul [cartographic material] : geological sketch map /
Map of Western Choiseul showing geological features. Relief shown by hachures.; "From material supplied by Dr. P.J. Coleman of the Geological Department, Sudney University, N.S.W., Australia".; Fig.6 from "British Solomon Islands Geological Record 1957 ...
Great Britain. Directorate of Overseas Surveys.
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The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
[Topographic maps of Sabah] [cartographic material].
Uncoloured topographic maps of Sabah, Malaysia, possibly compilation sheets for series DOS 333 (T833).; Each sheet is individually named and numbered.; "Lee Dong Young A.A. 18/3/58".
Great Britain. Colonial Office.
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