Results 111 to 120 of about 594,538 (299)

Rusya, İngiltere ve Doğu Rumeli Vilayetinin Kuruluşu

Vakanüvis Uluslararası Tarih Araştırmaları Dergisi, 2018
1877 – 1878 Osmanlı Rus savaşından sonra imzalanan Ayestefanos Antlaşması neticesinde ortaya çıkan “Büyük Bulgaristan” ideali Büyük Doğu Krizi sürecinde sarsılan Avrupa güç dengesinde daha derin krizler ortaya çıkardı. İngiltere ve Avusturya-Macaristan
Nadezhda VASİLEVA VASİLEVA
doaj  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Great Britain 1958

, 1958
Accompanied by "two tranparent overlays: one showing the transcribed and conjectured place names on the Gough map and the other their position on a modern map at a scale of 1/1,000,000." Published in tandem with "Map of Great Britain C.A.D. 1360 known as

core  

Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae

FEBS Open Bio, EarlyView.
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj, Eline M. F. de Lange, Klaas A. Sjollema, Ben N. G. Giepmans   +3 more
wiley   +1 more source

South Sandwich Islands 1927

, 1927
Relief shown by hachures.Includes note."Misc.
Great Britain. Hydrographic Office
core  

Inset Lead Weights: Trade and Identity in 9th- and 10th-century Viking armies in Britain and Ireland

Internet Archaeology
Viking armies introduced a bullion economy to 9th-century Britain and Ireland in which transactions were facilitated through the use of balances and weights.
Dawn Hadley, Julian D Richards, Mark Randerson, Rebekah Hiett   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source

East Coast of England 1911

, 1911
Depths shown by soundings.
Great Britain. Admiralty
core  

Reception, Accommodation, and Farewell of the Sultan Abdülaziz in Britain

Tarih Dergisi
With the exception of military campaigns in Ottoman history, the only Sultan who traveled to foreign countries and the only caliph who went to Christian countries as an ally was Sultan Abdülaziz. One of the most important stops during Sultan’s journey to
Emel Demir Görür
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source