Results 101 to 110 of about 594,538 (299)

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

open access: yesMolecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic   +10 more
wiley   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

Geological survey of Great Britain (England and Wales) [cartographic material] : solid and drift /

open access: yes, 1970
Subtitle varies: Solid geology and solid and drift geology, drift geology, solid and drift geology, solid with drift geology, solid and drift, solid.; Relief shown by contours, hachures, and spot heights. Depths shown by contours.; Title varies: 1:50,000
Great Britain. Ordnance Survey.
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The Last Reform in Macedonia: The British-Russian Reform Bill (8 March 1908)

open access: yesYakın Dönem Türkiye Araştırmaları
Macedonia, which was acquired by the Ottoman Empire from Bulgaria through the Berlin Treaty and mandated to undergo reforms, became a region of conflicting interests involving European countries and various ethnic groups.
Nuran Koltuk
doaj   +1 more source

‘Welcome to Britain'

open access: yes, 2006
Questions of asylum and immigration have taken centre stage in national and international debate and figure prominently in the domestic political agendas of wealthy states and nations. In Australia, Europe and the US, harsh and punitive asylum and immigration laws are being enacted incrementally and asylum-seekers are subject increasingly to detention.
openaire   +2 more sources

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

open access: yesMolecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico   +5 more
wiley   +1 more source

Psychological disorders in flying personnel of the Royal Air Force : investigated during the war 1939-45.

open access: yes, 1947
Includes index.; "Issued for the information and guidance of the senior executive and all medical officers of the Royal Air Force".; Electronic reproduction. Canberra, A.C.T.
Great Britain. Air Ministry
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Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

open access: yesMolecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth   +17 more
wiley   +1 more source

Report of city social survey--New Britain, Connecticut

open access: yes, 1935
Cover title.; "New Britain City Social Survey"--Page iii.; "November 1935."; "Operated as ERA Project No. 88-Fa-102 Under the Supervision of Emergency Relief Commission.

core  

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