Results 81 to 90 of about 7,144,441 (302)

Two Faces of NOTCH1 in Childhood Lymphoblastic T‐Cell Neoplasia: Prognostic Divergence of Mutational and Structural Aberrations

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT In pediatric patients, T‐cell lymphoblastic lymphoma (T‐LBL) survival exceeds 80%. Relapse remains associated with limited curative options. Frontline treatment is largely extrapolated from T‐cell acute lymphoblastic leukemia (T‐ALL) treatment, reflecting the ongoing debate, whether both entities represent distinct diseases or variants within ...
Marie C. Heider   +4 more
wiley   +1 more source

Rapid and deep-scale ubiquitylation profiling for biology and translational research

open access: yesNature Communications, 2020
Comprehensive protein ubiquitylation profiling by mass spectrometry typically requires large sample amounts, limiting its applicability to tissue samples.
Namrata D. Udeshi   +9 more
doaj   +1 more source

Mechanisms and potential treatments for declining olfactory function and neurogenesis in the ageing brain [PDF]

open access: yes, 2017
The role of olfactory function in maintaining quality of life and as a potential surrogate marker of neurogenic activity in the elderly brain is an underappreciated topic.
Broad, KD
core  

Blinatumomab Utilization in Pediatric B‐Cell Acute Lymphoblastic Leukemia: Experience From the Mountain West

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Blinatumomab is a bispecific T‐cell engager approved for the treatment of pediatric B‐cell acute lymphoblastic leukemia (B‐ALL). Outpatient home infusion reduces hospitalization burden and optimizes resource utilization, but is logistically challenging.
Angela Parra del Riego   +10 more
wiley   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Broad Histogram: An Overview

open access: yes, 2000
The Broad Histogram is a method allowing the direct calculation of the energy degeneracy $g(E)$. This quantity is independent of thermodynamic concepts such as thermal equilibrium.
de Oliveira, Paulo Murilo Castro
core   +1 more source

Random quantum magnets with broad disorder distribution

open access: yes, 2001
We study the critical behavior of Ising quantum magnets with broadly distributed random couplings (J), such that $P(\ln J) \sim |\ln J|^{-1-\alpha}$, $\alpha>1$, for large $|\ln J|$ (L\'evy flight statistics).
D. Karevski   +5 more
core   +4 more sources

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Broad-line type Ic Supernova SN 2014ad

open access: yes, 2018
We present optical and ultraviolet photometry, and low resolution optical spectroscopy of the broad-line type Ic supernova SN 2014ad in the galaxy PGC 37625 (Mrk 1309), covering the evolution of the supernova during $-$5 to +87 d with respect to the date
Anupama, G. C.   +6 more
core   +1 more source

Therapeutic Apheresis for Intravenous Methylprednisolone‐Refractory Neuromyelitis Optica Spectrum Disorder: Clinical and Radiological Outcomes in a Single‐Center Case Series

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Neuromyelitis optica spectrum disorder (NMOSD) is a relapsing autoimmune disease of the central nervous system. High‐dose intravenous methylprednisolone (IVMP) is the standard first‐line therapy for acute attacks, although some patients remain refractory.
Wataru Horiguchi   +5 more
wiley   +1 more source

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