Results 121 to 130 of about 39,746 (275)

Reframing Autism: A Theoretical Synthesis on Androgen-Mediated Cognitive Phenotypes and the Adaptive Feedback Model of Repetitive Behaviours

Revista Discapacidad, Clínica, Neurociencias
This article presents a comprehensive theoretical synthesis that critically examines and reframes two distinct facets of autism spectrum condition (ASC).
Michele Di Salvo
doaj   +1 more source

Emotion Dysregulation Predicts Impairments in Peer Interaction and Adaptive Functioning in Autistic Kindergartners

Autism Research, EarlyView.
ABSTRACT Emotion Dysregulation (ED) refers to difficulties in using adaptive strategies to modulate and express emotional arousal in socially appropriate ways. While ED contributes to developmental trajectories including peer engagement, academic achievement, and mental health in neurotypical children, its impact on autistic children is unclear.
Yeseul Shin, Deanna Swain, Jeongjin Kim, Seok‐Jun Hong, Catherine Lord, So Hyun Kim   +5 more
wiley   +1 more source

O Fenótipo Ampliado do Autismo em genitores de crianças com Transtorno do Espectro Autista - TEA

Psicologia: Teoria e Pesquisa
RESUMOPesquisadores têm identificado expressões mais leves de traços do Transtorno do Espectro do Autismo - TEA em pais e irmãos destes indivíduos, que são definidas como Fenótipo Ampliado do Autismo (FAA).
Renata Giuliani Endres, Simone Steyer Lampert, Jaqueline Bohrer Schuch, Tatiana Roman, Cleonice Alves Bosa   +4 more
doaj   +1 more source

Clinical impact of splicing in neurodevelopmental disorders. [PDF]

, 2020
Clinical exome sequencing is frequently used to identify gene-disrupting variants in individuals with neurodevelopmental disorders. While splice-disrupting variants are known to contribute to these disorders, clinical interpretation of cryptic splice ...
Farh, Kyle Kai-How, Sanders, Stephan J, Schwartz, Grace B   +2 more
core   +1 more source

Interval Timing Is Altered in Male Nrxn1+/− Mice: A Model of Autism Spectrum Disorder

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is characterized by impaired social interactions and communication, and increased repetitive and stereotypical behavior. Neuroimaging shows functional abnormalities in brain areas involved in temporal processing in autistic individuals, and they also show deficits in interval timing.
Kyle M. Roddick, Elias B. Habib, Richard E. Brown, Fuat Balcı   +3 more
wiley   +1 more source

Association of autistic personality traits with the EEG scores in non-clinical subjects during the facial video viewing

Вавиловский журнал генетики и селекции
A software information module of the experimental computer platform “EEG_Self-Construct” was developed and tested in the framework of this study. This module can be applied for identification of neurophysiological markers of self-referential processes ...
A. N. Savostyanov, D. A. Kuleshov, D. I. Klemeshova, M. S. Vlasov, A. E. Saprygin   +4 more
doaj   +1 more source

The 3‐Hit Metabolic Signaling Model for Autism Spectrum Disorder: A Summary

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a highly heritable yet environmentally sensitive neurodevelopmental condition whose biological heterogeneity has resisted a unifying causal explanation for over 100 years. The 3‐hit metabolic signaling model proposes that ASD arises from abnormal persistence of an evolutionarily conserved stress‐response ...
Robert K. Naviaux
wiley   +1 more source

Is it Possible to Assess the Two-Domain Definition of the Broad Autism Phenotype Using the Available Measurement Tools? [PDF]

J Autism Dev Disord, 2022
Godoy-Giménez M, González-Rodríguez A, Cañadas F, Estévez AF, Sayans-Jiménez P.   +4 more
europepmc   +1 more source

The E3 Ubiquitin Ligase UBE3B Regulates Synaptic Development and Cortical Network Activity

Autism Research, EarlyView.
ABSTRACT Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by impaired communication, abnormal social interactions, and restricted, repetitive behaviors. Pathogenic mutations in UBE3B result in neurodevelopmental disease, including intellectual disability, lack of speech, and ASD.
Shayal Vashisth, Aleya Shedd, Ariel Aiken, Solmi Cheon, Josh Bandopadhay, Kiran Kaur, Kimberly M. Huber, Maria H. Chahrour   +7 more
wiley   +1 more source

The Role of Microbiota Metabolites Propionic Acid, p‐Cresol, and 4‐Ethylphenyl Sulfate in Autism Susceptibility: A Systematic Review

Autism Research, EarlyView.
ABSTRACT The etiopathogenesis of Autism Spectrum Disorder (ASD) encompasses complex interactions between genetic and environmental risk factors. The high prevalence of gastrointestinal disorders in autistic individuals has propelled a growing interest in the possible involvement of gut dysbiosis in ASD pathogenesis.
Laura Sandoni, Lisa Asta, Nicole Giompaolo, Rinvil Renaldi, Alberto Amaretti, Maddalena Rossi, Antonio M. Persico   +6 more
wiley   +1 more source