Results 141 to 150 of about 39,746 (275)

Auditory Sensitivity in Autism: A Systematic Review of Mismatch Negativity and Mismatch Field Responses

open access: yesAutism Research, EarlyView.
ABSTRACT Auditory mismatch responses—mismatch negativity (MMN) and mismatch fields (MMF)—are well established electrophysiological markers of automatic auditory discrimination supported by short‐term sensory memory. These responses, typically elicited using passive oddball paradigms, are increasingly used to investigate sensory and language processing ...
Sara Cacciato‐Salcedo   +4 more
wiley   +1 more source

ACKR1/Duffy‐null genotype testing for clozapine: A guideline developed by the UK Centre of Excellence in Regulatory Science and Innovation in Pharmacogenomics (CERSI‐PGx)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Clozapine is licenced for treatment‐resistant schizophrenia and psychosis in Parkinson's disease. In the United Kingdom, there is a mandatory requirement for absolute neutrophil count (ANC) and white blood cell count (WBC) monitoring to safeguard against agranulocytosis.
Stephen Murtough   +29 more
wiley   +1 more source

KIAA2022/NEXMIF c.1882C>T (p.Arg628*) Variant in a Romanian Patient with Neurodevelopmental Disorders and Epilepsy: A Case Report and Systematic Review

open access: yesLife
Pathogenic variants in the NEXMIF gene are associated with a broad neurodevelopmental phenotype, including autism spectrum disorder (ASD), intellectual disability (ID), and epilepsy.
Catalina Mihaela Anastasescu   +6 more
doaj   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

open access: yesBulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Autism and abnormal development of brain connectivity [PDF]

open access: yes, 2004
Allen, G   +5 more
core   +1 more source

On the importance of including both sexes in animal studies – insights from home‐cage monitoring

open access: yesBiological Reviews, EarlyView.
ABSTRACT A review of behavioural studies using home‐cage monitoring (HCM) systems revealed that over 61% of studies used only male subjects, with only 24% including both sexes, despite evidence of substantial behavioural differences between male and female animals. This bias could influence the outcomes of biomedical research.
Maša Čater   +12 more
wiley   +1 more source

Genomic Insights Into Risperidone Treatment Outcomes in Children and Adolescents: Experience From a Psychiatric Hospital Serving Rural Youth

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Risperidone is a commonly used antipsychotic for treating psychiatric illness in children and adolescents. There is a large variability in risperidone response and discontinuation rates remain high. Pharmacogenomics offers the opportunity to improve risperidone outcomes, yet studies in pediatric populations are limited.
Jack W. Staples   +10 more
wiley   +1 more source

A Commentary on “Comparing Operationalizations of Eating Disorder Recovery Using a Comprehensive Lens: Physical, Behavioral, and Cognitive Domains” by Bardone‐Cone et al.

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Defining recovery in eating disorders remains a major challenge due to the absence of standardized, empirically validated criteria. Bardone‐Cone et al. (2025) address this gap by testing multidimensional, transdiagnostic recovery criteria spanning physical, behavioral, and cognitive domains.
Charlotte Bovenberg   +3 more
wiley   +1 more source

A Systematic Review and Meta‐Analysis of Psychological Therapies for Avoidant/Restrictive Food Intake Disorder (ARFID) in Adolescents and Adults

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective The efficacy of psychological therapies for adolescents and adults with avoidant/restrictive food intake disorder (ARFID) has yet to be rigorously analyzed through systematic review or meta‐analysis. Method We identified articles from seven databases that presented psychological therapies for adolescents and adults with ARFID. First,
Copeland G. Winten   +4 more
wiley   +1 more source

Psychiatric Morbidity Is Overrepresented in Young Girls at High Risk of Developing Anorexia Nervosa

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Psychiatric comorbidity frequently presents in anorexia nervosa (AN). Yet, the premorbid mental health status is relatively unknown. The aim of this study was to map out psychiatric morbidity and psychopathology among girls at familial high risk (FHR) of developing AN, thereby detecting possible underlying vulnerabilities preceding ...
Karin Dahlin   +3 more
wiley   +1 more source

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