Results 151 to 160 of about 18,861 (235)

Motivating paternal empathy and egalitarian attitudes to prevent maternal postpartum depressive symptoms: A randomized controlled trial

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the effectiveness of a motivation‐based intervention for fathers to enhance empathy and egalitarian gender‐role attitudes, aiming to prevent maternal postpartum depressive symptoms. Methods This was a single‐blind, parallel‐group randomized controlled trial conducted at a regional hospital in Japan.
Shuhei Terada   +6 more
wiley   +1 more source

Pioneering the canine model in microbiota–gut–brain research for social and affective disorders

open access: yesiMetaOmics, EarlyView.
This commentary highlights the translational potential of canine models in investigating the microbiota–gut–brain (MGB) axis, focusing on their relevance to human social cognition and affective disorders, including major depressive disorder and autism spectrum disorder.
Yun Yu   +8 more
wiley   +1 more source

The gut microbiome organ

open access: yesiMeta, EarlyView.
The gut microbiome can be conceptualized as a distributed organ‐like functional system with spatially structured organization, broad biochemical capacity, and continuous bidirectional communication with the host. By transforming dietary, host‐derived, and environmental substrates into bioactive metabolites with endocrine‐like, immunomodulatory, and ...
Yang Bi   +22 more
wiley   +1 more source

Maternal and infant gut microbiome

open access: yesiMeta, EarlyView.
The maternal–infant continuum involves critical windows of host–microbiota co‐adaptation. Preconception, maternal and paternal microbiomes modulate immunity and reproduction. During pregnancy, a gut–placenta axis emerges, where microbial metabolites influence fetal growth or contribute to complications like gestational diabetes mellitus (GDM ...
Huidi Wang   +25 more
wiley   +1 more source

The regulation of stem cell fate and its application in neural regeneration

open access: yesInterdisciplinary Medicine, EarlyView.
Regulating stem cell fate is crucial for neural regeneration. This review summarizes key physical, biological, and chemical strategies and their applications in repairing nerve injuries, providing new insights for regenerative medicine. Abstract Regulating the fate of stem cells (SCs) is a key technical problem in the field of regenerative medicine and
Yuexin He   +3 more
wiley   +1 more source

Microbial metabolite indole‐3‐propionic acid preserves astrocytic mitochondrial mitofusin 2 to limit neuroinflammation after traumatic brain injury

open access: yesInterdisciplinary Medicine, EarlyView.
Following traumatic brain injury, indole‐3‐propionic acid (IPA) directly targets the aryl hydrocarbon receptor on astrocytes in the peri‐lesional cortex; this suppresses interferon regulatory factor 1‐driven transcription of the E3 ubiquitin ligase RFFL (ring finger and FYVE‐like domain containing E3 ubiquitin protein ligase).
Ziwen Zhang   +22 more
wiley   +1 more source

Are sensory processing difficulties in infancy predictive of child mental health at 5‐years? Findings from the Etude Longitudinale Francaise depuis l'Enfance French national birth cohort

open access: yesJCPP Advances, EarlyView.
Abstract Background People with neurodevelopmental and mental health conditions have been demonstrated to have elevated rates of sensory processing (SP) difficulties in research and practice but the temporal order of this relationship is unclear. Methods This study sought to investigate whether SP difficulties in infancy predicted mental health at 5 ...
Emma Butler   +2 more
wiley   +1 more source

Reward processing in children with affective dysregulation

open access: yesJCPP Advances, EarlyView.
Abstract Background Affective dysregulation (AD) in children is characterized by irritability, anger, and frequent intense temper outbursts. Considerable evidence implies altered processing of frustration about missed rewards, but few studies investigated the preceding and thus potentially predictive reward anticipation and initial delivery processing ...
Pascal‐M. Aggensteiner   +11 more
wiley   +1 more source

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