Results 171 to 180 of about 39,746 (275)

Artificial intelligence in the assessment of epilepsy‐related genetic mutations: Learned from GABAA receptors and GABA transporter 1

Epilepsia Open, EarlyView.
Abstract This review examines how recent genetic and technological advances have transformed our understanding and treatment of genetic epilepsies (GEs), with a focus on disorders involving GABAA receptors (GABRs) and the GABA transporter 1 (GAT‐1) encoded by SLC6A1.
Juexin Wang, Jing‐Qiong Kang
wiley   +1 more source

Genetic landscape of patients with atypical absence status epilepticus: A systematic review

Epilepsia Open, EarlyView.
Abstract Atypical absence status epilepticus (AASE) is a rare subtype of nonconvulsive status epilepticus (NCSE), characterized by clouding of consciousness and continuous or fluctuating epileptiform activity, generally at a frequency below 3 Hz. Only sparse literature exists on the genetic conditions associated with it.
Maria Cristina Cioclu, Giada Giovannini, Stefano Meletti   +2 more
wiley   +1 more source

Faecal Microbiota Transplantation in Anorexia Nervosa: A Systematic Review of Methodologies, Outcomes, and Challenges With Recommendations for Future Studies

European Eating Disorders Review, EarlyView.
ABSTRACT Objective Anorexia nervosa (AN) is a severe psychiatric disorder displaying an altered gut microbiome. Faecal microbiome transplantation (FMT) has emerged as a powerful research tool and potential treatment option in AN due to the microbiome‐gut‐brain axis. Current studies are limited and reveal variable FMT protocols.
Anna C. Thelen, Nele M. Korten, Larissa Blischke, Clara Voelz, Cordian Beyer, Jochen Seitz, Stefanie Trinh   +6 more
wiley   +1 more source

Dietary and biomarker‐guided strategies as supportive measures in the fragile X syndrome

Food Biomacromolecules, EarlyView.
Abstract The fragile X syndrome (FXS) is an inherited neurodevelopmental disorder that primarily affects males, often resulting in an IQ below 55, while about two‐thirds of females also experience intellectual disability. Physical features may include an elongated face, prominent ears, finger joint laxity, and enlarged testes in males.
Jailan E. El Halawani, Reem R. AlOlaby
wiley   +1 more source

Broad autism phenotype features of Chinese parents with autistic children and their associations with severity of social impairment in probands. [PDF]

BMC Psychiatry, 2015
Shi LJ, Ou JJ, Gong JB, Wang SH, Zhou YY, Zhu FR, Liu XD, Zhao JP, Luo XR.   +8 more
europepmc   +1 more source

Motivating paternal empathy and egalitarian attitudes to prevent maternal postpartum depressive symptoms: A randomized controlled trial

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To evaluate the effectiveness of a motivation‐based intervention for fathers to enhance empathy and egalitarian gender‐role attitudes, aiming to prevent maternal postpartum depressive symptoms. Methods This was a single‐blind, parallel‐group randomized controlled trial conducted at a regional hospital in Japan.
Shuhei Terada, Ayako Morita, Aya Isumi, Chiharu Ugajin, Yu Par Khin, Shiori Shakagori, Takeo Fujiwara   +6 more
wiley   +1 more source

Mentalizing difficulties are transdiagnostic and explain links between mental health and neurodevelopmental symptoms and social adjustment in school‐aged children

JCPP Advances, EarlyView.
Growing evidence suggests that difficulties reasoning about others' thoughts, feelings and desires (called ‘mentalizing’ or ‘theory of mind’) cut across many mental health and neurodevelopmental conditions but studies have yet to test this claim directly.
Rory T. Devine, Imogen Byrne, Venelin Kovatchev   +2 more
wiley   +1 more source

Tactile hypo‐responsivity in autism: Examining potential for diagnostic relevance

JCPP Advances, EarlyView.
The study reported in this paper examined the utility of a brief tactile reactivity assessment in differentiating autistic children from those with other neurodevelopmental concerns and the association between tactile responsivity, autism symptomatology, developmental level, and adaptive skills.
Girija Kadlaskar, Rebecca McNally Keehn, Riley Rozniarek, Nina Pan Fujii, Brandon Keehn   +4 more
wiley   +1 more source

Patterns of help‐seeking for mental health problems in 1001 self‐identified neurodivergent adolescents who self‐harm

JCPP Advances, EarlyView.
Adolescents who self‐harm are also more likely to seek support from informal than formal sources and least likely to seek support online. But neurodivergent adolescents who self‐harm are more likely to seek any and especially formal (pastoral school staff or mental health services) support than their peers.
Simona Skripkauskaite, Galit Geulayov, the OxWell Study Team, Mina Fazel, Rohan Borschmann   +4 more
wiley   +1 more source

Mechanistic trials, therapy and developmental science—An exemplar from early autism care

JCPP Advances, EarlyView.
Abstract Background Mechanistic design and analysis in clinical trials remains relatively rare in child mental health and autism, despite the considerable value that it could have in developing therapy practice and in illuminating basic science. Clinical trials themselves continue to have insufficient influence on actual clinical practice in child ...
Jonathan Green
wiley   +1 more source