Results 191 to 200 of about 19,233 (265)

The role of rare copy number variants in early‐onset depression

JCPP Advances, EarlyView.
Abstract Background Depression is a highly heterogeneous condition. Depression with an onset in childhood and early adolescence has a worse clinical course, is more heritable, and shows a lower genetic correlation with other depression subtypes, than does later‐onset depression.
Charlotte A. Dennison, Ida Sønderby, Miguel Garcia‐Argibay, Victoria Powell, Amy Shakeshaft, Lucy Riglin, Elliott Rees, Michael O’Donovan, Henrik Larsson, Ole Andreassen, Alexandra Havdahl, Joanna Martin, Anita Thapar   +12 more
wiley   +1 more source

Delineation of Facial Dysmorphology in Males With Creatine Transporter Defect. [PDF]

Am J Med Genet A
Perreault J, Porter FD, Nowaczyk MJM.
europepmc   +1 more source

Isolating transdiagnostic effects reveals specific genetic profiles in psychiatric disorders

JCPP Advances, EarlyView.
Abstract Background Evidence indicates substantial genetic overlap between psychiatric diagnoses. Accounting for these transdiagnostic effects can sharpen research on disorder‐specific genetic architecture and patterns of comorbidity. Methods We applied genomic structural equation modeling to genome‐wide association study summary statistics from 11 ...
Engin Keser, Wangjingyi Liao, Andrea G. Allegrini, Kaili Rimfeld, Thalia C. Eley, Robert Plomin, Margherita Malanchini   +6 more
wiley   +1 more source

Implications of attention‐deficit/hyperactivity disorder diagnostic timing on mental health service utilisation in young adult females: A population‐based record linkage cohort study

JCPP Advances, EarlyView.
Abstract Background Sex differences in the frequency and timing of attention‐deficit/hyperactivity disorder (ADHD) diagnosis exist. While there are multiple known individual and wider consequences for young females with delayed or undiagnosed ADHD, little is known about mental health service utilisation (HSU) impacts.
Estelle Alderson, Nicholas Bowden, Laurie McLay, Ben Beaglehole, Philip J. Schluter   +4 more
wiley   +1 more source

Association between ADHD symptoms and device‐measured physical activity and sedentary behavior in childhood: A population‐based twin study

JCPP Advances, EarlyView.
Abstract Background Attention‐deficit/hyperactivity disorder (ADHD) symptoms are associated with adverse health outcomes; this may be partially due to unhealthy lifestyle factors such as low physical activity (PA) and high sedentary behavior (SED). However, this association remains unclear.
Narda Ontiveros, Björg Helgadottir, Örjan Ekblom, Anna Ohlis, Aylin Mehren, Camilla A. Wiklund   +5 more
wiley   +1 more source

Common cause versus dynamic mutualism: Insights into ADHD's common comorbidities

JCPP Advances, EarlyView.
Abstract Background Contemporary classification systems differ in their conceptualization of ADHD as either an externalizing or neurodevelopmental condition, with both perspectives promoting the common cause model as an explanation of ADHD's comorbidity.
Zheyue Peng, Ashley L. Watts
wiley   +1 more source

Childhood trauma as a mediator between autistic traits and depression: Evidence from the ALSPAC birth cohort. [PDF]

Psychol Med
Underwood JFG, Madley-Dowd P, Dardani C, Hull L, Kwong ASF, Pearson RM, Hall J, Rai D.   +7 more
europepmc   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source

Identifying biomarkers of neurodevelopmental and mental health outcomes in a prospective longitudinal cohort of South African children: design and feasibility of the Safe Passage BONO study. [PDF]

Pilot Feasibility Stud
Springer PE, Brink LT, Potter M, Mackay W, Smit PC, du Plessis C, Koziel J, Del Bianco T, Oakley BFM, Haartsen R, Jones EJH, Munafò M, Odendaal HJ, Murphy DG, Loth E.   +14 more
europepmc   +1 more source