Results 191 to 200 of about 18,861 (235)

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

The Microbiome as a Mirror: Distinguishing Healthy Individuals From Chronic Constipated Patients and Identifying Those With Hidden Psychiatric Burden

Microbiota Medicine Research, EarlyView.
Gut microbiota signatures distinguish chronic constipated patients from healthy individuals, supporting noninvasive diagnostic potential. Despite challenges in identifying psychiatric‐related comorbidities, microbial alterations, particularly in neurotransmitter and inflammatory pathways, lay the groundwork for future companion diagnostics and ...
Hongyan Qi, Ting Yu, Weichen Liu, Ya Jiang, Die Chen, Li Gao, Hui Li, Yurong Tang   +7 more
wiley   +1 more source

Microglia in autism spectrum disorder: heterogeneity, immunometabolism, and synapse-related pathways. [PDF]

Front Immunol
Lian A, He M, Zhang H, Yang Y.
europepmc   +1 more source

Editorial: Enhancing the social skills and social competence for children and adolescents with autism spectrum disorder. [PDF]

Front Psychiatry
Budisteanu M.
europepmc   +1 more source

Neuropsychiatric Phenotype in a Patient with Neurodevelopmental Disorder with or Without Early-Onset Generalized Epilepsy (NEDEGE). [PDF]

Genes (Basel)
Szczęśniak D, Wilczek A, Mroczek M.
europepmc   +1 more source

DDX3X Syndrome: Clinical, Neuroimaging, AI-Assisted Facial Profiling and Genotype-Phenotype Correlations. [PDF]

Genes (Basel)
Sadok SH, Serra AI, Pias-Peleteiro LD, Chaparro DS, Xiol C, Armstrong J, Guillén-Navarro E, Martínez-Monseny AF.   +7 more
europepmc   +1 more source

NeuroDev: etiology and experience of neurodevelopmental disorders in Kenya and South Africa

Kipkemoi P, O’Heir E, Amin M, Stenton SL, Baddoo W, Brand H, Bruwer Z, Bryant S, Chepkemoi E, Christ B, Eastman E, Fourie C, Fu JM, Galvin A, Hall S, Kim HA, Khan F, Kipkoech C, Kombe M, Mapenzi R, Melly B, van der Merwe C, Mkubwa B, Murugasen S, Mwangasha K, Mwangi P, Mwasambu S, Ngombo A, Nyale J, Osei-Owusu I, Ringshaw JE, Russell KA, Samocha KE, Sanchis-Juan A, Singer-Berk M, VanNoy GE, Zieff M, Talkowski ME, O’Donnell-Luria A, Austin-Tse C, Newton CR, Abubakar A, Donald KA, Robinson EB.   +43 more
europepmc   +1 more source

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The Broad Autism Phenotype Questionnaire

Journal of Autism and Developmental Disorders, 2006
The broad autism phenotype (BAP) is a set of personality and language characteristics that reflect the phenotypic expression of the genetic liability to autism, in non-autistic relatives of autistic individuals. These characteristics are milder but qualitatively similar to the defining features of autism. A new instrument designed to measure the BAP in
Molly Losh, J Steven Reznick, Losh Molly   +2 more
exaly   +3 more sources

The Broad Autism Phenotype–International Test (BAP-IT): A two-domain-based test for the assessment of the broad autism phenotype

Autism
The broad autism phenotype is the phenotypic expression of the primary characteristics of autism. However, currently available tests do not agree with the two-domain operationalization of broad autism phenotype or autism, and their internal structure has shown instability across applications.
Angel García-Pérez, Pablo Sayans-Jiménez, Fernando Cañadas Perez   +2 more
exaly   +4 more sources