Results 61 to 70 of about 2,414 (194)

Managing High‐Risk Drug Interactions With Nirmatrelvir/Ritonavir: Experience From a Dedicated Pharmacology Advice Service

Clinical and Translational Science, Volume 19, Issue 3, March 2026.
ABSTRACT Nirmatrelvir boosted with ritonavir is a key antiviral against COVID‐19, yet ritonavir's potent CYP3A4 inhibition exposes patients to numerous drug–drug interactions. To make prescribing safer, a national proactive system providing expert pharmacology advice was implemented in France.
Youssef Libiad, Bénédicte Franck, Camille Tron, Sébastien Lalanne, Christelle Boglione‐Kerrien, Fabrice Taïeb, Marie‐Clémence Verdier, Florian Lemaitre   +7 more
wiley   +1 more source

Case Report: Rapid resolution of psychogenic cough in an adolescent following bromazepam treatment

Frontiers in Psychiatry
BackgroundSomatic cough syndrome, formerly termed psychogenic cough or habit cough, is an under-recognized cause of chronic cough in pediatric populations, characterized by repetitive, dry, and honking cough that is absent during sleep.
Mansour Alharbi
doaj   +1 more source

Patterns of Drug and Polydrug Detection in Drivers Suspected of Driving Under the Influence of an Intoxicant in Ireland 2019–2020: A Latent Class Analysis

Drug and Alcohol Review, Volume 45, Issue 1, January 2026.
ABSTRACT Introduction Driving under the influence of drugs is a major risk factor for road traffic collisions. While increasing harms are observed in relation to polydrug use, evidence is needed about this issue in the context of road safety. We examined polydrug use patterns in drivers providing samples for toxicological analysis in Ireland between ...
Louise Durand, Aoife O'Kane, Richard Maguire, Denis Cusack, Eamon Keenan, Gráinne Cousins   +5 more
wiley   +1 more source

Successful Benzodiazepine Deprescribing Assisted by Orengedokuto: A Case Series

Traditional &Kampo Medicine, Volume 13, Issue 2, August 2026.
Shinji Sato, Akito Hisanaga
wiley   +1 more source

Antidepressant Adverse Reactions in Adult and Older Adult Populations: A Comparative Study From the Portuguese Pharmacovigilance System (2010–2020)

Journal of Clinical Pharmacy and Therapeutics, Volume 2026, Issue 1, 2026.
Background The use of antidepressants in Portugal has been increasing, raising concerns about their potential to cause adverse drug reactions (ADRs), particularly in vulnerable populations. This study aimed to characterize all ADRs associated with antidepressant use reported between January 1, 2010, and December 31, 2020, and to compare these findings ...
Ana Catarina Coelho, Cristina Monteiro, Maria Vaz Patto, Anjali Chauhan   +3 more
wiley   +1 more source

Quality Assessment of Melatonin Supplements Marketed in Brazil: Alarming Discrepancies

Journal of Food Quality, Volume 2026, Issue 1, 2026.
Melatonin (MLT) is a hormone naturally produced by the pineal gland at night. It has multifunctional properties, including the regulation of circadian rhythms, antioxidant effects, and potential treatments for insomnia and jet lag. Due to simplified regulatory processes, many supplements may present quality deviations.
Elizane Langaro, Nathalia de Souza Rodrigues, Ana Carolina Bertoletti de Marchi, Charise Dallazem Bertol, Vivian Killet   +4 more
wiley   +1 more source

Utilização de benzodiazepínicos por idosos de umaestratégia de saúde da família: implicações para enfermagem Utilización de benzodiazepinas en ancianos de una estrategia de salud familiar: implicaciones para enfermería The use of benzodiazepines in the elderly in a family health strategy: implications in

Escola Anna Nery, 2011
Os benzodiazepínicos são medicamentos que podem causar riscos aos idosos. Este estudo teve como objetivo verificar e analisar a prevalência da utilização de benzodiazepínicos por idosos cadastrados em uma Estratégia Saúde da Família de Diamantina - Minas
Paulo Celso Prado Telles Filho, Alex Rogério das Chagas, Marcos Luciano Pimenta Pinheiro, Antônio Moacir de Jesus Lima, Ana Maria Sertori Durão   +4 more
doaj   +1 more source

Sleep quality and its correlates in people with epilepsy: A multicenter cross‐sectional study in Germany

Epilepsia, Volume 66, Issue 12, Page 4764-4779, December 2025.
Abstract Objective Sleep disturbances and epilepsy are closely interrelated. This study aimed to examine associations between sleep quality, affective symptoms, and quality of life (QoL) in people with epilepsy (PWE), and to identify clinical and sociodemographic factors linked to impaired sleep. Methods We conducted a multicenter cross‐sectional study
Johann Philipp Zöllner, Catrin Mann, Laurent Willems, Felix von Podewils, Lisa Langenbruch, Laura Bierhansl, Susanne Knake, Katja Menzler, Juliane Schulz, Bernadette Gaida, Felix Rosenow, Adam Strzelczyk   +11 more
wiley   +1 more source

Multidimensional Evaluation of Lisdexamfetamine: Pharmacology, Therapeutic Use, Toxicity and Forensic Implications

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
Structure of lisdexamfetamine dimesylate, its active metabolite d‐amphetamine and the essential amino acid l‐lysine, along with the mechanism of action and primary pharmacological and adverse effects associated with lisdexamfetamine dimesylate. TAAR1, trace amine‐associated receptor; VMAT, vesicular monoamine transporter; DAT, dopamine transporter; NAT,
Mariana Silva‐Carvalho, Daniel José Barbosa, Diana Dias da Silva, Ricardo Jorge Dinis‐Oliveira   +3 more
wiley   +1 more source

Effect of Evening Bromazepam Administration on Blood Pressure and Heart Rate in Mild Hypertensive Patients

, 2019
Aim: To assess the effects of chronic evening oral administration of bromazepam alone or in combination with propranolol on ambulatory blood pressure (BP) and heart rate (HR) in mild hypertensive subjects.
Bosone, Daniele, Fogari, Roberto, Cotta Ramusino, Matteo, Perini, Giulia, Ghiotto, Natascia, Costa, Alfredo, Dangelo, Angela, Zoppi, Annalisa   +7 more
core   +1 more source