Bromocriptine-associated ototoxicity [PDF]
The Journal of Laryngology & Otology, 2007 Three patients treated with bromocriptine for chronic hepatic encephalopathy showed audiometric evidence of bilateral sensori-neural hearing-loss. Audiometrically, the hearing improved in all three patients when the bromocriptine dosage was reduced, thus
Ballantyne, J, Lanthier, PL, Morgan, MY
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Atherosclerosis enhances the efficacy of liposome-encapsulated bromocriptine in reducing the incidence of prolactinemia in pituitary tumors [PDF]
Journal of NanobiotechnologyIntranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang +12 more
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Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism. [PDF]
PLoS ONEBromocriptine, generally regarded as a dopamine D2 receptor agonist, has been used to treat patients with type 2 diabetes in the USA; however, its mechanisms of action including the receptors that mediate its anti-diabetic effects remain unclear ...
Hiroshi Tsuneki +11 more
doaj +2 more sources
Surgical Management of Gestational Gigantomastia: A Case Report Highlighting Therapeutic Intervention [PDF]
Plastic and Reconstructive Surgery, Global OpenSummary:. Gigantomastia is an exceedingly rare condition characterized by extraordinary growth of breasts during pregnancy, and its underlying etiology remains elusive.
Misha A. Lemma, MD +4 more
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Dual pancreatic adrenergic and dopaminergic signaling as a therapeutic target of bromocriptine
iScience, 2022 Summary: Bromocriptine is approved as a diabetes therapy, yet its therapeutic mechanisms remain unclear. Though bromocriptine’s actions have been mainly attributed to the stimulation of brain dopamine D2 receptors (D2R), bromocriptine also targets the ...
Despoina Aslanoglou +14 more
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Study on Synergistic Effect of Bromocriptine and Sitagliptin in Streptozotocin-induced Diabetic Rats [PDF]
Journal of Clinical and Diagnostic Research, 2021 Introduction: Diabetes mellitus is a potentially morbid condition with high prevalence worldwide. Restoration of euglycemia in type 2 diabetes mellitus is difficult to achieve due to its multifactorial pathogenesis and frequently requires multiple ...
Govindaraj Nileshraj +3 more
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The role of MAPK11/12/13/14 (p38 MAPK) protein in dopamine agonist-resistant prolactinomas
BMC Endocrine Disorders, 2021 Background Prolactinoma is a functional pituitary adenoma that secretes excessive prolactin. Dopamine agonists (DAs) such as bromocriptine (BRC) are the first-line treatment for prolactinomas, but the resistance rate is increasing year by year, creating ...
Shuman Wang +6 more
doaj +1 more source
Impact of Nano-Bromocriptine on Egg Production Performance and Prolactin Expression in Layers
Animals, 2021 The current study aimed to investigate the potential use of nano-bromocriptine in improving the laying performance of late laying hens by modulating the prolactin gene expression.
Ahmed Dawod +7 more
doaj +1 more source
Bromocriptine monotherapy overcomes prostate cancer chemoresistance in preclinical models
Translational Oncology, 2023 Chemoresistance is a major obstacle in the clinical management of metastatic, castration-resistant prostate cancer (PCa). It is imperative to develop novel strategies to overcome chemoresistance and improve clinical outcomes in patients who have failed ...
Lijuan Bai +15 more
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Bromocriptine in Parkinsonism [PDF]
BMJ, 1974 Bromocriptine, a drug acting directly upon dopaminergic receptors, has been found to have a significant therapeutic action in a double-blind study of 20 patients with idiopathic Parkinsonism who were already receiving conventional therapy, including levodopa.
L. E. Claveria +5 more
openaire +3 more sources