Results 51 to 60 of about 14,648 (212)

Bromocriptine, a Dopamine (D2 ) Receptor Agonist, Used Alone and in Combination with Glipizide in Sub–Therapeutic Doses to Ameliorate Hyperglycaemia [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Bromocriptine, an ergot derivative, is an agonist at the dopamine 2 receptor and a sympatholytic. It is a well established drug in Parkinsonism, hyperprolactinaemia and acromegaly and it has various other clinical indications like ...
Harish Kumar V.S., Vinutha M.B., Pradeep A.N., Sathisha Aithal, Sindhura Reddy Baleed, Umakant N. Patil   +5 more
doaj   +1 more source

Bromocriptine and insulin secretion

Bioscience Reports, 1982
The dopaminergic drug bromocriptine inhibited the release of insulin from isolated mouse pancreatic islets. The effect was counteracted by haloperidol or pimozide. It is suggested that insulin release may be inhibited through activation of D-2 dopaminergic receptors in the pancreatic beta-cells.
Eva Gagerman, Ezz-Eldin S. M. El-Denshary, Inge-Bert Täljedal, Nabila A. Ismail, Janove Sehlin   +4 more
openaire   +3 more sources

Maternal and fetal outcomes in subsequent pregnancies after peripartum cardiomyopathy: A systematic review and meta‐analysis

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
Our systematic review and meta‐analysis found that subsequent pregnancy after peripartum cardiomyopathy presents significant maternal and fetal risks. This study provides quantification of risks to begin to fill the current evidence gap, however is limited by a paucity of existing data.
Rebecca Man, Jack Le Vance, Hafsa Abdullahi, Clare Davenport, Mengshi Yuan, Laura Ormesher, Sana Usman, James Castleman, Caroline Fox, Lucy Hudsmith, R. Katie Morris, Victoria Hodgetts Morton   +11 more
wiley   +1 more source

Nerve growth factor and bromocriptine: a sequential therapy for human bromocriptine-resistant prolactinomas. [PDF]

, 1995
Nerve growth factor (NGF) administration to athymic mice with transplanted human bromocriptine-resistant prolactinoma, results in the expression of dopamine D-2 receptors in the tumour and restores sensitivity to subsequent treatment with bromocriptine ...
Balsari, A., Boroni, F., Giovanelli, M., Losa, M., Missale, C., Spano, P. F.   +5 more
core   +2 more sources

The Application of Polymeric Nanoparticles as Drug Delivery Carriers to Cells in Neurodegenerative Diseases

Cell Proliferation, EarlyView.
Polymeric nanoparticles represent promising drug (gene) delivery carriers to the brain due to their unique advantages to facilitate the penetration of blood–brain barrier and endocytosis of neuronal cells in neurodegenerative diseases. ABSTRACT In spite of great advances in modern medicine, there are a few effective strategies for the treatment of ...
Lian Jin, Libo Nie, Yan Deng, Ghulam Jilany Khana, Nongyue He   +4 more
wiley   +1 more source

Bromocriptine improves glucose tolerance in obese mice via central dopamine D2 receptor-independent mechanism.

PLoS ONE
Bromocriptine, generally regarded as a dopamine D2 receptor agonist, has been used to treat patients with type 2 diabetes in the USA; however, its mechanisms of action including the receptors that mediate its anti-diabetic effects remain unclear ...
Hiroshi Tsuneki, Takahiro Maeda, Mayumi Takatsuki, Takahiro Sekine, Satsuki Masui, Kengo Onishi, Ryuta Takeda, Masanori Sugiyama, Takeshi Sakurai, Masashi Yanagisawa, Tsutomu Wada, Toshiyasu Sasaoka   +11 more
doaj   +1 more source

Prolactin delays hair regrowth in mice [PDF]

, 2006
Mammalian hair growth is cyclic, with hair-producing follicles alternating between active (anagen) and quiescent (telogen) phases. The timing of hair cycles is advanced in prolactin receptor (PRLR) knockout mice, suggesting that prolactin has a role in ...
Ashby, M.G., Blazek, K., Craven, A.J., Nixon, A.J., Ormandy, C.J., Pearson, A.J., Wilkins, Richard J.   +6 more
core   +2 more sources

Effect of pergolide treatment on insulin dysregulation in horses and ponies with pituitary pars intermedia dysfunction

Equine Veterinary Journal, EarlyView.
Abstract Background Due to the high frequency of laminitis reported for both conditions, the relationship between pituitary pars intermedia dysfunction (PPID) and insulin dysregulation (ID), and the potential role of dopamine in modifying insulin secretion, requires further investigation.
Nicolas C. Galinelli, Nicholas J. Bamford, Madison L. Erdody, Skye A. Mackenzie, Tobias Warnken, Patricia A. Harris, Martin N. Sillence, Simon R. Bailey   +7 more
wiley   +1 more source

Overexpression of the short isoform of the dopamine D2 receptor causes diet‐induced obesity and hyperglycemia in mice

Journal of Neuroendocrinology, EarlyView.
Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez, Lei Cheng, Qing Chang, Paul E. Gold, Diego Perez‐Tilve, YanYan Wang   +5 more
wiley   +1 more source

A review of neuroleptic malignant syndrome : incidence and features in Malta [PDF]

, 1995
This paper describes Malta’s first sample of Neuroleptic Malignant Syndrome (NMS) and reviews the current literature. A retrospective sample of all diagnosed cases of NMS was reviewed using Pope’s (1986) criteria. Twelve cases were identified yielding an
Grech, Anton, Saliba, Joseph R.
core