Results 71 to 80 of about 32,807 (303)

Neuroleptic Malignant Syndrome: A Case Report of the Oldest Man in Literature

Clinical Case Reports, Volume 13, Issue 10, October 2025.
Radiographic findings in a 96 year old‐man with neuroleptic malignant syndrome highlights the importance of early recognition and attention to systemic complications. ABSTRACT A diagnosis of neuroleptic malignant syndrome (NMS) was made in a 96‐year‐old man, representing the oldest documented case in the existing medical literature.
Forouzan Elyasi, Mohsen Aarabi, Majidreza Adelani, Arghavan Fariborzifar, Marzieh Azizi   +4 more
wiley   +1 more source

The Impact of Metformin on Plasma Prolactin Levels in Antipsychotics‐Treated Men With Hyperprolactinemia and Early‐Onset Androgenic Alopecia

Clinical Endocrinology, Volume 103, Issue 4, Page 513-522, October 2025.
ABSTRACT Objective Metformin decreases elevated levels of pituitary hormones. Little is known about the association between the reproductive axis and hormonal effects of this drug. The purpose of our study was to investigate whether activity of the hypothalamic‐pituitary‐gonadal axis determines metformin action on prolactin levels in men with prolactin
Robert Krysiak, Karolina Kowalcze, Marek Krzystanek, Witold Szkróbka, Bogusław Okopień   +4 more
wiley   +1 more source

Effectivity of Bromocriptine Administration Towards Prolactin Positive Breast Cancer Receiving Anthracycline-Based Chemotherapy: A Literature Review

Acta Medica Indonesiana, 2023
Breast cancer is among the deadliest gynecology cancers in the world. However, the management of advanced-stage breast cancer is often harder as a result of chemoresistance.
Muhammad Yadi Permana, Sarwanti Sarwanti, Siti Fauziah   +2 more
doaj   +2 more sources

Defining CYP3A4 Structural Responses to Substrate Binding. Raman Spectroscopic Studies of a Nanodisc-incorporated Mammalian Cytochrome P450 [PDF]

, 2011
Resonance Raman (RR) spectroscopy is used to help define active site structural responses of nanodisc-incorporated CYP3A4 to the binding of three substrates: bromocriptine (BC), erythromycin (ERY), and testosterone (TST).
Denisov, Ilia G., Grinkova, Yelena V., Kincaid, James R., Mak, Piotr J., Sligar, Stephen G.   +4 more
core   +3 more sources

Cyclic nucleotide signaling as a drug target in retinitis pigmentosa

FEBS Letters, Volume 599, Issue 18, Page 2557-2570, September 2025.
Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää, Ahmed B. Montaser, Henri Leinonen   +2 more
wiley   +1 more source

Dissociation between the effects of somatostatin (SS) and octapeptide SS-analogs on hormone release in a small subgroup of pituitary- and islet cell tumors [PDF]

, 1997
The effects of somatostatin (SS-14 and/or SS-28) and of the three octapeptide SS-analogs that are available for clinical use (octreotide, BIM-23014 and RC-160) on hormone release by primary cultures of 15 clinically ...
Herder, W.W. (Wouter) de, Hofland, L.J. (Leo), Koetsveld, P.M. (Peter) van, Kros, J.M. (Johan), Lamberts, S.W.J. (Steven), Uffelen, C. van, Uitterlinden, P. (Piet), Visser-Wisselaar, H.A. (Heleen), Waaijers, M. (Marlijn), Zuyderwijk, J.   +9 more
core   +3 more sources

The effect of short-term metformin treatment on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired glucose tolerance: a pilot study

Endocrine, 2014
Metformin was found to affect plasma levels of some pituitary hormones. This study was aimed at investigating whether metformin treatment has an impact on plasma prolactin levels in bromocriptine-treated patients with hyperprolactinaemia and impaired ...
R. Krysiak, J. Okrzesik, B. Okopień
semanticscholar   +1 more source

Society for Maternal‐Fetal Medicine Consult Series #73: Diagnosis and management of right and left heart failure during pregnancy and postpartum

Pregnancy, Volume 1, Issue 5, September 2025.
Abstract Heart failure is a major contributor to maternal morbidity and mortality. Pregnancy is a state of hemodynamic stress, and normal physiologic changes of pregnancy may mimic signs of heart failure. Prepregnancy counseling, multidisciplinary care, and referral to a center with expertise in managing pregnant patients with heart failure can help ...
Society for Maternal‐Fetal Medicine (SMFM), Afshan B. Hameed, Ernesto Licon, Arthur Jason Vaught, Raj Shree, SMFM Publications Committee   +5 more
wiley   +1 more source

Reformulating Pro-Oxidant Microglia in Neurodegeneration [PDF]

, 2019
In neurodegenerative diseases, microglia-mediated neuroinflammation and oxidative stress are central events. Recent genome-wide transcriptomic analyses of microglial cells under different disease conditions have uncovered a new subpopulation named ...
Alonso Bellido, Isabel María, Burguillos García, Miguel Ángel, Cruz Hernández, Luis, Espinosa Oliva, Ana María, García Domínguez, Irene, García Revilla, Juan, Herrera Carmona, Antonio José, Martínez de Pablos, Rocío, Roca Ceballos, María Angustias, Rodríguez Gómez, José Antonio, Ruiz Laza, Rocío, Santiago Pavón, Martiniano, Sarmiento Soto, Manuel, Venero Recio, José Luis   +13 more
core   +2 more sources

Pituitary adenomas, some diagnostic and therapeutical aspects [PDF]

, 1994
The treatment of almost all types of pituitary adenomas has changed considerably in recent years. New types of drugs as well as improved application forms of older drug therapies are now becoming more and more available for everyday treatment of patients
Herder, W.W. (Wouter) de, Lamberts, S.W.J. (Steven), Lely, A-J. (Aart-Jan) van der   +2 more
core   +1 more source