Results 51 to 60 of about 12,698 (210)

Dopamine-mediated behaviours produced in naive mice by bromocriptine plus SKF 38393

, 1988
The ability of bromocriptine and SKF38393 (2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1 H-3-benzazepine) to produce some dopamine-mediated behaviours has been assessed in mice.
Mayko Hashizume, D M Jackson, S B Ross
core   +1 more source

Dopamine D2 receptor agonist, bromocriptine, remodels adipose tissue dopaminergic signalling and upregulates catabolic pathways, improving metabolic profile in type 2 diabetes

Molecular Metabolism, 2021
Background and objectives: The therapeutic effects of the dopamine D2 receptor (D2R) agonist, bromocriptine, in type 2 diabetes (T2D) have been attributed to central nervous system actions.
G. Tavares, D. Marques, C. Barra, D. Rosendo-Silva, A. Costa, T. Rodrigues, P. Gasparini, B.F. Melo, J.F. Sacramento, R. Seiça, S.V. Conde, P. Matafome   +11 more
doaj   +1 more source

Altered Retinal Dopamine Homeostasis in Murine Models of Retinitis Pigmentosa

Journal of Neurochemistry, Volume 170, Issue 9, September 2026.
Dopamine is an important catecholamine chemical messenger in the light‐sensing retina of the eye, where it serves multiple modulatory functions related to vision. This research studied the changes in the retinal dopamine system in two mouse models (P23H and rd10) of retinitis pigmentosa, which is a disease group of inherited retinal diseases that lead ...
Katri Vainionpää, Eerik Lappalainen, Anna Nilsson, Ida Pavela, Tommi Torsti, Umair Seemab, Elina Mäkinen, Reza Shariatgorji, Per E. Andrén, Aaro Jalkanen, Markus M. Forsberg, Henri Leinonen   +11 more
wiley   +1 more source

Atherosclerosis enhances the efficacy of liposome-encapsulated bromocriptine in reducing the incidence of prolactinemia in pituitary tumors

Journal of Nanobiotechnology
Intranasal drug delivery via nanocarriers has long been a research focus for enhancing drug concentration in the brain. However, the strategy of exploiting blood–brain barrier (BBB) alterations in atherosclerotic mouse models to enhance nanoparticle ...
Zhe Zhang, Guangyu Jia, Qi Wang, Yamei Yu, Xiaolong Tang, Heqing Zheng, Xinyu Yang, Yao Xiao, Yangrui Ou, Jingjing Jiang, Hua Guo, Ye Wang, Shiyong Li   +12 more
doaj   +1 more source

A Rare Constellation of Peripartum Cardiomyopathy Manifesting With Multiple Thromboembolic Phenomena in a 15‐Year‐Old

Clinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama, Bibiana Kazaura, Theresia E. Lutufyo, Baraka E. Mrisho, Hery O. Kimwela, Marco E. Nyakasalule, Ronald M. Costantini, Eliya Msemwa, Florence Malamso, George Assenga, Julius Kinyange, Josephine R. Laswai, Fabian M. Kamana, Godfery Malangwa, David S. Mazengo, Raymond Leiya, Andrea S. Hondo, Masuma Gulamhussein, Happiness J. Mathew, Paul P. Mwasapi, Phillip S. Muhochi, Hakolo L. Mgaya, Moa E. Kalunga, Brendan P. Shayo, Amani E. Senso, Leonia N. Ndakamaze, Tuzo Lyuu, Anna A. Sanga, Rosemary P. Minja, Deusdedit Ndilanha, Emmanuel J. Magandi, Nkulikiye Kanani, Anthony J. Gyunda, Immaculate R. Goima, Justus L. Ishengoma, Janet L. Mtenga, Flora N. Ndobho, Kigocha L. Okengo, Paschal N. Kulwijila, Pius C. Njingo   +39 more
wiley   +1 more source

Prolactin and Triiodothyronine Modulate Seasonal Variation in Brown Adipose Tissue in Djungarian Hamsters

Journal of Experimental Zoology Part A: Ecological and Integrative Physiology, Volume 345, Issue 7, Page 710-718, August 2026.
ABSTRACT Seasonal photoperiodic cycles regulate energy rheostasis in many animals. Brown adipose tissue (BAT) and the liver are key metabolic organs that show remarkable plasticity in response to photoperiodic conditions. Prolactin (PRL) and thyroid hormones are endocrine signals that transmit neural‐derived photoperiodic time measurement encoding to ...
Sayantan Sur, Grace Payling, Calum Stewart, Avalene Tan, Caitlin Diggle, Tyler J. Stevenson   +5 more
wiley   +1 more source

Table_1_Repurposing of Bromocriptine for Cancer Therapy.docx

, 2018
Bromocriptine is an ergot alkaloid and dopamine D2 receptor agonist used to treat Parkinson’s disease, acromegaly, hyperprolactinemia, and galactorrhea, and more recently diabetes mellitus.
Yoshikazu Sugimoto (151140), Henry Johannes Greten (5828054), Ean-Jeong Seo (3695242), Thomas Efferth (33075)   +3 more
core   +1 more source

Bromocriptine, a Dopamine (D2 ) Receptor Agonist, Used Alone and in Combination with Glipizide in Sub–Therapeutic Doses to Ameliorate Hyperglycaemia [PDF]

Journal of Clinical and Diagnostic Research, 2013
Introduction: Bromocriptine, an ergot derivative, is an agonist at the dopamine 2 receptor and a sympatholytic. It is a well established drug in Parkinsonism, hyperprolactinaemia and acromegaly and it has various other clinical indications like ...
Harish Kumar V.S., Vinutha M.B., Pradeep A.N., Sathisha Aithal, Sindhura Reddy Baleed, Umakant N. Patil   +5 more
doaj   +1 more source

Exploring the Therapeutic Potential of Oenothera laciniata: Antioxidant, Anti‐Hyperglycemic and Histopathological Activities Using In Vitro and In Vivo Approaches

Food Science &Nutrition, Volume 14, Issue 7, July 2026.
Graphical abstract illustrating the therapeutic potential of Oenothera laciniata: antioxidant, anti‐hyperglycemic and histopathological activities using in vitro and in vivo approaches. ABSTRACT This study investigate the crude ethanolic extract of Oenothera laciniata (EOL) and its solvent fractions n‐hexane (NHOL), dichloromethane (DCMOL), ethyl ...
Dur‐E‐Najaf Khan, Syed Muhammad Mukarram Shah, Muska Mahabat Khan, Rehman Zafar, Muhammad Saeed Jan, Muhammad Ibrar, Abdur Rauf, Yahya S. Al‐Awthan, Omar S. Bahattab, Rakibur Rahman   +9 more
wiley   +1 more source

Effectivity of Bromocriptine Administration Towards Prolactin Positive Breast Cancer Receiving Anthracycline-Based Chemotherapy: A Literature Review

Acta Medica Indonesiana, 2023
Breast cancer is among the deadliest gynecology cancers in the world. However, the management of advanced-stage breast cancer is often harder as a result of chemoresistance.
Muhammad Yadi Permana, Sarwanti Sarwanti, Siti Fauziah   +2 more
doaj   +2 more sources