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Prolactin (PRL) is an anterior pituitary hormone which has its principle physiological action in initiation and maintenance of lactation. In human reproduction, pathological hyperprolactinemia most commonly presents as an ovulatory disorder and is often ...
Abha Majumdar, Nisha Sharma Mangal
doaj +7 more sources
Macroprolactinemia: a New Cause of Hyperprolactinemia
Hyperprolactinemia is not only seen in pregnancy but also in several pathological conditions such as prolactin (PRL) secreting pituitary adenoma (prolactinoma), intracranial tumors compressing the pituitary stalk or hypothalamus, and PRL stimulative ...
Naoki Hattori
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Study of Clinical Profile and Early Response to Dopamine Agonist Therapy in Patients of Hyperprolactinemia: Experience at a Tertiary Care Centre of Nepal [PDF]
Introduction: Pathological hyperprolactinemia is medically treatable condition with dopamine agonist therapy. This research was aimed to study clinical profiles of patients of hyperprolactinemia started on cabergoline and assess clinical, biochemical ...
Richa Nepal +5 more
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Preview An elevated serum prolactin level has many causes, including pituitary tumors, hypothalamic disease, and certain drugs. Dr Kaye reviews the various causes of hyperprolactinemia and discusses evaluation and treatment options for this common metabolic disorder.
Kaur J, Bhusal K.
europepmc +5 more sources
Hyperprolactinemia as a side effect of using antipsychotics In Schizophrenic Patients
Introductions: Antipsychotics are still the mainstay of schizophrenia management. Antipsychotics are antagonistic to postsynaptic dopamine receptors in the brain.
Syaiful Anwar, Khairina
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Background: Hyperprolactinemia is one of the most common causes of infertility in women. The prevalence of pituitary tumors is 25-30% among infertile participants with hyperprolactinemia.
Elahe Dehghan +4 more
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BACKGROUND: Prolactin is a hormone of the pituitary gland whose main function is the production of milk. Hyperprolactinemia is defined as an increase in prolactin levels above 25 μg/L in women and 20 μg/L in men.
Moeber Mahzari +6 more
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Management of Hyperprolactinemia in Clinical Practice
Background & objectives: Hyperprolactinemia is defined as an increased prolactin level above the normal reference range, in women more than 25 ng/dl; with a prevalence rate of 10% in the general population.
Bayar Ahmed Qasim +4 more
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Prolactin (PRL) has direct and indirect effects on bone metabolism. Experimental studies showed that in the presence of high PRL levels bone resorption was increased as well as bone formation was suppressed. Increased PRL levels in humans caused a reduction in sex hormone levels which turn may have detrimental effects on bone.
di Filippo L. +3 more
openaire +3 more sources
Usefulness of prolactin levels in predicting the etiology of hyperprolactinemia in a cohort of 770 patients [PDF]
Objective Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin levels in predicting the etiology of ...
Lucio Vilar +18 more
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