Results 1 to 10 of about 990 (199)
Macroprolactin: an overlooked reason of hyperprolactinemia [PDF]
Journal of Laboratory Medicine, 2019 Background Immunoassays show variability in the detection of macroprolactin. The aim of this study was to detect the frequency of macroprolactinemia in hyperprolactinemic patients and the problems encountered in routine clinical practice.
Sabahattin Muhtaroglu +1 more
exaly +5 more sources
The validation of macroprolactin analysis by polyethylene glycol precipitation using Fujirebio Lumipulse [PDF]
Practical Laboratory Medicine, 2022 size exclusion in all m assay 5 times with 0.9% NaCl. The diluted samples were diluted twice with vortexed for 10 s. the were centrifuged 10800 g (14000 for 6 min. Both the supernatant and the originally diluted samples × 0.9% NaCl) were and the recovery
Febe C Vermue, Sjoerd A A Van Den Berg
exaly +5 more sources
Journal of Human Reproductive Sciences, 2021 The prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%–17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
Krishnaprabha Gautam +5 more
doaj +3 more sources
Antipsychotics-induced hyperprolactinemia and screening for macroprolactin [PDF]
Biochemia Medica, 2020 Introduction High prolactin (PRL) concentrations are found in laboratory test results of patients on majority of antipsychotic drugs. Prevalence rates and degrees of severity of hyperprolactinemia (HPRL) based on PRL concentration may depend on the ...
N. Ruljancic +7 more
semanticscholar +7 more sources
FRI314 Prolactinoma And Macroprolactin; A Diagnostic Dilemma [PDF]
J Endocr Soc, 2023 Disclosure: A. Farooqi: None. S. Dewan: None. J. Jun: None. Prolactin is a 199 amino acid, 23 (Kilo Dalton) kDa protein secreted by pituitary lactotroph cells.
Aneeba Farooqi, S. Dewan, J. Jun
europepmc +3 more sources
Macroprolactin: From laboratory to clinical practice
Endocrinología Diabetes Y Nutrición (English Ed ), 2022 Prolactin measurement is very common in standard clinical practice. It is indicated not only in the study of pituitary adenomas, but also when there are problems with fertility, decreased libido, or menstrual disorders, among other problems.
Betina Biagetti +2 more
exaly +7 more sources
The Effect of Metformin on Pituitary Function in Postmenopausal Women with Subclinical Hypothyroidism and Macroprolactinemia: A Single-Center Prospective Case–Control Study [PDF]
PharmaceuticalsBackground/Objectives: Metformin inhibits secretory function of overactive thyrotrophs, gonadotrophs, and lactotrophs. The clinical significance of an excess of high-molecular-weight prolactin (macroprolactinemia) remains unclear.
Robert Krysiak +3 more
doaj +3 more sources
Endocrine Journal, 2018 The clinical influence of macroprolactin (MPRL) is not clearly understood and the rate of patients potentially affected by MPRL is unknown. We investigated the influence of MPRL on the onset of galactorrhea and estimated the rate of patients with a ...
Akiko Hasegawa, Haruko Hiraike
exaly +5 more sources
Macroprolactin and macroprolactinaemia: A narrative review
Magna Scientia Advanced Research and Reviews, 2023 Background: Macroprolactin is a heteropolymeric complex of monomeric prolactin and immunoglobulin G (IgG) with little or no biological activity in vivo.
Izuchukwu ECO +2 more
semanticscholar +2 more sources
The Importance Of Macroprolactin In The Diagnosis Of Hyperprolactinemia [PDF]
Series of Endocrinology, Diabetes and Metabolism, 2021 This article provides a brief review of macroprolactin (MPRL) – what, why, how, and when. Prolactin (PRL) secretion is uniquely controlled by tonic dopamine inhibition.
T. Aw, Cs Lau
semanticscholar +2 more sources