Results 1 to 10 of about 580 (145)

The Effect of Metformin on Pituitary Function in Postmenopausal Women with Subclinical Hypothyroidism and Macroprolactinemia: A Single-Center Prospective Case–Control Study [PDF]

Pharmaceuticals
Background/Objectives: Metformin inhibits secretory function of overactive thyrotrophs, gonadotrophs, and lactotrophs. The clinical significance of an excess of high-molecular-weight prolactin (macroprolactinemia) remains unclear.
Robert Krysiak, Witold Szkróbka, Karolina Kowalcze, Bogusław Okopień   +3 more
doaj   +3 more sources

The Validation of Macroprolactin Analysis by Polyethylene Glycol Precipitation Using Fujirebio Lumipulse [PDF]

Practical Laboratory Medicine, 2022
Sjoerd A A van den Berg, Febe C Vermue
exaly   +4 more sources

Comparison of urinary prolactin and serum/urine prolactin ratio in hyperprolactinemic and macroprolactinemic patients [PDF]

BMC Endocrine Disorders
Background Biologically, the monomeric form of prolactin is the most active. In measurement methods, all forms of prolactin are included in the assay; therefore, the presence of macroprolactin, causes a false increase in prolactin and misdiagnosis of ...
Behnam Ein-Mozaffari, Akbar Aliasgharzadeh, Farzad Najafipour, Azam Moslemi, Mitra Niafar, Vahideh Sadra, Nasser Aghamohammadzadeh, Jalil Houshyar, Halimeh Amirazad   +8 more
doaj   +2 more sources

Macrohormones in endocrinology: prevalence, clinical impact, and diagnostic approaches [PDF]

Frontiers in Endocrinology
Macrohormones also called macromolecules or macrocomplexes are described as an antigen-antibody complex, consisting of monomeric hormones bound to immunoglobulins. These molecules exhibit minimal or no biological activity.
Agata Bronisławska, Olivia Cyran-Stańczak, Olivia Cyran-Stańczak, Robert Bronisławski, Alicja Solecka, Agata Berlińska, Agata Berlińska, Renata Świątkowska-Stodulska, Renata Świątkowska-Stodulska, Jarosław Piotr Jendrzejewski, Jarosław Piotr Jendrzejewski   +10 more
doaj   +2 more sources

Prevalence of Macroprolactinaemia in Women with Hyperprolactinaemia: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Macroprolactinaemia causes asymptomatic hyperprolactinaemia in many patients which leads to misdiagnosis, inappropriate investigation and needless treatment in these patients.
Flavia Almeida, Alap Christy, Varsha Birla, Raj Jatale, Kirti Chadha   +4 more
doaj   +2 more sources

Polyendocrine–Metabolic Profile in Adolescents and Young Women with Ovulatory Dysfunction: A Cross-Sectional Study [PDF]

Biology
(1) Background: Ovulatory dysfunction (OD) is frequently the first clinical expression of an underlying polyendocrine or metabolic disturbance. In the context of the international consensus renaming polycystic ovary syndrome (PCOS) as polyendocrine ...
Juan Pablo Del Río, Hugo Soto, Patricio Contreras, Álvaro Becerra, Camila Contreras-Rojo, Manuel E. Cortés, Pilar Vigil   +6 more
doaj   +2 more sources

The Correlation Between DRD2 and COMT Gene Polymorphisms, HPT and HPG Axes Functions, and Antipsychotic Drug-Induced Hyperprolactinemia and Macroprolactinemia [PDF]

Neuropsychiatric Disease and Treatment
Zhenhua Wang,1 Jing Li,2 Haizhi Chen,1 Haiying Jin,1 Shiliang Wang,1 Xuqiang Hu1 1Department of Psychiatry, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, People’s Republic of China; 2Center for Disease ...
Wang Z, Li J, Chen H, Jin H, Wang S, Hu X   +5 more
doaj   +2 more sources

Diagnosis of hyperprolactinemia in women: A Position Statement from the Brazilian Federation of Gynecology and Obstetrics Associations (Febrasgo) and the Brazilian Society of Endocrinology and Metabolism (SBEM) [PDF]

Archives of Endocrinology and Metabolism
Hyperprolactinemia is a frequent cause of menstrual irregularity, galactorrhea, hypogonadism, and infertility. The most common etiologies of hyperprolactinemia can be classified as physiological, pharmacological, and pathological.
Andrea Glezer, Heraldo Mendes Garmes, Leandro Kasuki, Manoel Martins, Paula Condé Lamparelli Elias, Vania dos Santos Nunes Nogueira, Ana Carolina Japur de Sá Rosa-e-Silva, Gustavo Arantes Rosa Maciel, Cristina Laguna Benetti-Pinto, Andrea Prestes Nácul   +9 more
doaj   +2 more sources

Mild hyperprolactinemia in women with polycystic ovary syndrome. Insights from a large cross-sectional study [PDF]

Journal of Clinical & Translational Endocrinology
Background: Hyperprolactinemia is an exclusion criterion for polycystic ovary syndrome (PCOS), albeit PCOS itself is argued to induce mild hyperprolactinemia.
Manuel Luque-Ramírez, Alejandra Quintero-Tobar, María Ángeles Martínez-García, Sara de Lope Quiñones, María Insenser, Lía Nattero-Chávez, Héctor Francisco Escobar-Morreale   +6 more
doaj   +2 more sources

Prevalence of Macroprolactinaemia by Polyethylene Glycol Precipitation Method: A Cross-sectional Study [PDF]

National Journal of Laboratory Medicine, 2021
Introduction: Macroprolactin, an immunoreactive molecule resulting from association of monomeric Prolactin (mPRL) and immunoglobulin G is a significant cause of misdiagnosis, unnecessary radiological investigation and treatment for ...
RAGHUNATH BHATTACHARYYA, KHEYA MUKHERJEE, KASTURI MUKHERJEE, DEBOJYOTI BHATTACHARJEE, SHUBHO CHOWDHURI   +4 more
doaj   +1 more source