Permeation of polyethylene glycols across the tympanic membrane [PDF]
Localized and non-invasive delivery of therapeutics across barriers in the body is challenging. Examples include the flux of drugs across the tympanic membrane (TM) for the treatment of middle ear infections, and across the round window to treat inner ...
Wei Zhang +6 more
doaj +2 more sources
Mechano-Induced Synthesis of Polyethylene Glycols α,ω-DiSubstituted with 4-(PAH)-1H-1,2,3-Triazoles in Presence of In Situ-Generated Bronze Microparticles as Catalyst [PDF]
A method for the mechanochemical CuAAC click reaction (Cu+-promoted azido–alkyne cycloaddition) in the presence of bronze powder/copper beads without the use of a pre-introduced catalyst and ligands with greener prospect is presented. A new type of tri-,
Mohammed S. Mohammed +6 more
doaj +2 more sources
Laser Microinterferometry for API Solubility and Phase Equilibria: Darunavir as a Case Example [PDF]
Background: The solubility and phase behavior of APIs are crucial for the development of medicines and ensuring their stability. However, conventional experimental approaches often do not allow for the precise determination of phase transitions and ...
Veronika Makarova +2 more
doaj +2 more sources
Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of rheumatoid arthritis and other ...
Hüseyin Acar +4 more
doaj +1 more source
Investigation on Acoustic Parameters of Monosodium Glutamate Food Preservative in an Aqueous Solution of PolyEthylene Glycols (400 and 600) [PDF]
This paper aims to examine the impact of social media on mental health. Aqueous monosodium glutamate (MSG) was mixed with polyethylene (PEG400 and PEG600), and the resulting mixture was weighed and subjected to acoustic density and velocity measurements.
Firdaus Ansari Ammara, Juglan K.C.
doaj +1 more source
Formulation, Physiochemical, and Microbial Assay of Henna Oil Vaginal Suppository Formulated with Polyethylene Glycol Bases [PDF]
Background: Persian Medicine is one of the oldest and richest complementary and alternative options in the field of medicine and has a comprehensive medical system.
Payam Khazaeli +5 more
doaj +1 more source
Relationship between Friction Coefficient, Viscosity and Compressibility of Polyethylene Glycol
An ultrasonic liquid processor with the frequency of 20 kHz was used to cleave a principal chain in a polyethylene glycol molecule. The amount of the lubricant molecules cleaved by the ultrasonic disruption was evaluated by the kinematic viscosity ...
Kazuaki Hachiya, Tatsuya Nitta
doaj +1 more source
The chemical modification of synthetic oligonucleotides has recently been investigated to improve their pharmacological utilization. In addition to chemical alterations of the backbone and of the heterocyclic bases, their conjugation with amphiphylic ...
Bonora GM, Zaramella S, Veronese FM
doaj +1 more source
Background/Aims: Recently, 1-L polyethylene glycol-ascorbic acid (PEG-Asc) has been used to reduce the volume of preparation agents in colonoscopy. This clinical trial aimed to compare the efficacy and safety of two types of 1-L PEG-Asc (CleanViewAL ...
Suh Hyun Choi +10 more
doaj +1 more source
Investigation of the Influence of Antioxidant Compositions on Development of Microbiological Spoilage in Storage of Fruits [PDF]
The studies are devoted to the scientific grounding of expedience of after-harvest processing by antioxidant compositions for preventing the development of pathogenic microflora on fruit surfaces during a long storage.
Atanasova, V. (Vita) +8 more
core +6 more sources

