Results 41 to 50 of about 180,351 (273)

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Porous polyethylene and proplast [PDF]

open access: yes, 1984
A comparative animal study showed that, after implantation in skull defects in guinea pigs, porous high-density polyethylene (PHDPE) was substantially better anchored in the bone than Proplast, and had greater stability of form and structure. In Proplast,
Handrock, M.   +2 more
core   +1 more source

FORMULATION AND STABILITY OF HEPTAMINOL SUPPOSITORIES PART III: Chemical Stability of Heptaminol Suppositories [PDF]

open access: yesBulletin of Pharmaceutical Sciences. Assiut University, 1984
The chemical stability of Heptaminol base in four different suppository bases was investigated in absence and presence of several stabilizers. The stability was found decreasing in the order of: Glycerogelatin, Cacao-Butter, Witepsol-E-75, and then ...
Siham Ali, Mohamed El-Miligi, Ali Kassem
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Endovascular Juxtarenal Aortic Aneurysm Repair Using the ALTO Abdominal Stent Graft System: The First Case Series

open access: yesVascular Specialist International, 2022
The ALTO abdominal stent graft system (Endologix Inc., Irvine, CA, USA) is a latest-generation polymer-based device used to treat patients with abdominal aortic aneurysms.
Fotios O. Efthymiou   +6 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Original and generic preservation solutions in organ transplantation. A new paradigm? [PDF]

open access: yesActa Cirúrgica Brasileira, 2020
Solid organ transplantation is a very complex process, in which the storage of the graft in a preservation solution is mandatory in order to extend ischemic times and contain further damage.
Joan Roselló-Catafau   +5 more
doaj   +1 more source

Direct condensation of carboxylic acids with polyethylene glycols catalyzed by Sc(OTf)3

open access: yes, 2002
Esterification of soluble polymers by direct condensation of equimolar amounts of carboxylic acids with polyethylene glycols is achieved using catalytic Sc(OTf)3 in toluene for the first time. The first esterification of a soluble polymer by condensation
Shameem Sultana, S.   +11 more
core   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

Efficacy and safety of polyethylene glycol in combination with linaclotide versus polyethylene glycol alone for colonoscopy: a grade-assessed systematic review and meta-analysis [PDF]

open access: yesClinical Endoscopy
Background/Aims The effectiveness of colonoscopy largely depends on the quality of bowel preparation. Polyethylene glycol (PEG) is commonly used but has certain limitations.
Umar Akram   +11 more
doaj   +1 more source

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