Results 31 to 40 of about 24,847 (275)

Antimicrobial effect of intracanal substances

Journal of Applied Oral Science, 2007
In some situations, endodontic infections do not respond to therapeutic protocol. In these cases, it is suggested the administration of an alternative intracanal medication that presents a wide spectrum of action and has an in-depth effect on the root ...
Cláudia de Moura Carreira, Silvana Soléo Ferreira dos Santos, Antônio Olavo Cardoso Jorge, José Luiz Lage-Marques   +3 more
doaj   +1 more source

EFFECT OF SOLID DISPERSIONS ON THE SOLUBILITY OF METRONIDAZOLE

Фармация и фармакология (Пятигорск), 2021
The aim of the work is to study the effect of solid dispersions using polyethylene glycols of various molecular weights on the solubility of metronidazole in water. Metronidazole is an antimicrobial and antiprotozoal drug.
I. I. Krasnyuk (Jr.), S. R. Naryshkin, I. I. Krasnyuk, A. V. Belyatskaya, O. I. Stepanova, I. S. Bobrov, V. G. Yankova, J. V. Rau, A. N. Vorobiev   +8 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

FEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa, Konstantinos Makryniotis, Theofani‐Iosifina Sousani, Evangelos Topakas, Vangelis Daskalakis, Maria Dimarogona   +5 more
wiley   +1 more source

Anaphylactic Shock Caused by Ingestion of Polyethylene Glycol [PDF]

Intestinal Research, 2015
Colonoscopy is the current standard method for evaluation of the colon. The diagnostic accuracy and therapeutic safety of colonoscopy depend on the quality of colonic cleansing and preparation.
Sun Hee Lee, Jae Myung Cha, Joung Il Lee, Kwang Ro Joo, Hyun Phil Shin, Il Hyun Baek, Jung Won Jeon, Jun Uk Lim, Jung Lok Lee, Hyae Min Lee, Young-Hak Cho   +10 more
doaj   +1 more source

Efficacy and Safety of TJP-008 Compared to 2 L PEG with Ascorbate in Colon Cleansing: A Randomized Phase 3 Trial

Gut and Liver, 2022
Background/Aims: Polyethylene glycol (PEG)-based bowel preparations are effective cleansing agents for colonoscopy. However, they require relatively large volumes to be used even with agents such as 2 L PEG with ascorbate (2LPEG).
Ja Seol Koo, Jeong-Sik Byeon, Bo-In Lee, Sung-Ae Jung, Tae Il Kim, Yoon Tae Jeen   +5 more
doaj   +1 more source

Correlation between Grafting Density and Confined Crystallization Behavior of Poly(ethylene glycol) Grafted to Silica [PDF]

, 2019
The interfacial interactions of polymer-nanoparticles have dramatical effects on the crystallization behavior of grafted polymers. In this study, methoxy polyethylene glycol (MPEG) (molecular weights 750, 2000 and 4000 g mol−1) was grafted onto amino ...
Müller Sánchez, Alejandro Jesús, Shui, Yudan, Su, Yunlan, Wang, Dujin, Wen, Xiangning, Zhao, Weiwei   +5 more
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Identification of best available thermal energy storage compounds for low-to-moderate temperature storage applications in buildings [PDF]

, 2018
Award-winning paper at III International Congress and V National on Sustainable Construction and Eco-Efficient Solutions (CICSE) March 2017Over the last 40 years different thermal energy storage materials have been investigated with the aim of enhancing ...
Barrios Padura, Ángela, Chacartegui, Ricardo, Lizana Moral, Francisco Jesús, Ortiz Domínguez, Carlos, Valverde Millán, José Manuel   +4 more
core  

Evaluation of water properties in HEA–HEMA hydrogels swollen in aqueous-PEG solutions using thermoanalytical techniques [PDF]

, 2015
Hydrogels are polymeric materials used in many pharmaceutical and biomedical applications due to their ability to form 3D hydrophilic polymeric networks, which can absorb large amounts of water.
A Ribeiro, B Slaughter, CC Lin, D Cetin, D Kee De, Ellen V. Hackl, Gustavo M. B. Tiguman, I Katime, Irina Ermolina, J Ostrowska-Czubenko, J Wang, JA Bouwstra, JK Kim, JM Wood, JM Wood, JS Jovašević, JS Mackie, KA George, KH Hong, M Salmerón-Sánchez, MS John, N Tomar, NA Peppas, OV Khutoryanskaya, PL Ritger, S Amin, S Baumgartner, S Tomić, SM Paterson, T Goda, T Henning, TJ Dursch, Vitaliy V. Khutoryanskiy, VJ McBrierty, Y Sakai   +34 more
core   +1 more source