Permeation of polyethylene glycols across the tympanic membrane [PDF]
Giant, 2021 Localized and non-invasive delivery of therapeutics across barriers in the body is challenging. Examples include the flux of drugs across the tympanic membrane (TM) for the treatment of middle ear infections, and across the round window to treat inner ...
Wei Zhang +6 more
doaj +2 more sources
Mechano-Induced Synthesis of Polyethylene Glycols α,ω-DiSubstituted with 4-(PAH)-1H-1,2,3-Triazoles in Presence of In Situ-Generated Bronze Microparticles as Catalyst [PDF]
MoleculesA method for the mechanochemical CuAAC click reaction (Cu+-promoted azido–alkyne cycloaddition) in the presence of bronze powder/copper beads without the use of a pre-introduced catalyst and ligands with greener prospect is presented. A new type of tri-,
Mohammed S. Mohammed +6 more
doaj +2 more sources
Laser Microinterferometry for API Solubility and Phase Equilibria: Darunavir as a Case Example [PDF]
PharmaceuticsBackground: The solubility and phase behavior of APIs are crucial for the development of medicines and ensuring their stability. However, conventional experimental approaches often do not allow for the precise determination of phase transitions and ...
Veronika Makarova +2 more
doaj +2 more sources
INTERACTION OF TEMAZEPAM WITH CERTAIN MACROMOLECULES: IV- PHASE DIAGRAM OF TEMAZEPAM-POLYETHYLENE GLYCOL BINARY SYSTEMS [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1988 Differential scanning calorimetery and hot stage microscopy were used to build up temperature-composition phase diagrams for temazepam-polyethylene glycol 2000, 4000 and 6000 physical mixtures and comprecipitates. The phase diagram showed the systems to
B. Mulley +3 more
doaj +1 more source
Acta Cirúrgica Brasileira, 2022 Purpose: Liver damage caused by drugs and other chemicals accounts for about 5% of all cases. Methotrexate (MTX), a folic acid analogue, is a first-line synthetic antimetabolite agent routinely used in the treatment of rheumatoid arthritis and other ...
Hüseyin Acar +4 more
doaj +1 more source
Investigation on Acoustic Parameters of Monosodium Glutamate Food Preservative in an Aqueous Solution of PolyEthylene Glycols (400 and 600) [PDF]
E3S Web of Conferences, 2023 This paper aims to examine the impact of social media on mental health. Aqueous monosodium glutamate (MSG) was mixed with polyethylene (PEG400 and PEG600), and the resulting mixture was weighed and subjected to acoustic density and velocity measurements.
Firdaus Ansari Ammara, Juglan K.C.
doaj +1 more source
Formulation, Physiochemical, and Microbial Assay of Henna Oil Vaginal Suppository Formulated with Polyethylene Glycol Bases [PDF]
Iranian Journal of Medical Sciences, 2020 Background: Persian Medicine is one of the oldest and richest complementary and alternative options in the field of medicine and has a comprehensive medical system.
Payam Khazaeli +5 more
doaj +1 more source
Relationship between Friction Coefficient, Viscosity and Compressibility of Polyethylene Glycol
Tribology Online, 2008 An ultrasonic liquid processor with the frequency of 20 kHz was used to cleave a principal chain in a polyethylene glycol molecule. The amount of the lubricant molecules cleaved by the ultrasonic disruption was evaluated by the kinematic viscosity ...
Kazuaki Hachiya, Tatsuya Nitta
doaj +1 more source
Biological Procedures Online, 1998 The chemical modification of synthetic oligonucleotides has recently been investigated to improve their pharmacological utilization. In addition to chemical alterations of the backbone and of the heterocyclic bases, their conjugation with amphiphylic ...
Bonora GM, Zaramella S, Veronese FM
doaj +1 more source
Influence of certain adsorbents on the in vitro availability of lidocaine from some suppository bases [PDF]
Bulletin of Pharmaceutical Sciences. Assiut University, 1999 The effect of porous calcium silicate (Florite R) and microcryst. cellulose (Avicel PH 102) on the physicochem. characterizations and dissoln. rate of lidocaine (LD) and consequently the effect on the in vitro release of LD from some suppository bases ...
M. Abd El-Mohsen +3 more
doaj +1 more source