Gigantomastia and Macroprolactinemia Responding to Cabergoline Treatment: A Case Report and Minireview of the Literature [PDF]
Case Reports in Endocrinology, 2016 Background. Macroprolactinemia is defined as predominance of high molecular weight prolactin forms in the circulation. Although macroprolactin is considered as a biologically inactive molecule, some authorities suggest treatment in symptomatic cases ...
Fatma Dilek Dellal +5 more
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Journal of Human Reproductive Sciences, 2021 The prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%–17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
Krishnaprabha Gautam +5 more
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The importance of routine screening for macroprolactin in symptomatic patients with idiopathic hyperprolactinemia [PDF]
Anais da Faculdade de Medicina de Olinda, 2018 Objective: To evaluate the importance of screening for macroprolactin in symptomatic patients with apparent idiopathic hyperprolactinemia. Methods: During 20 months, the prevalence of macroprolactinemia was evaluated among consecutive symptomatic female
Lucio Vilar +11 more
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Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia [PDF]
Taiwanese Journal of Obstetrics & Gynecology, 2017 The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum +5 more
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Macroprolactinemia: Diagnostic, Clinical, and Pathogenic Significance [PDF]
Clinical and Developmental Immunology, 2012 Macroprolactinemia is characterized by a large molecular mass of PRL (macroprolactin) as the main molecular form of PRL in sera, the frequent elevation of serum PRL (hyperprolactinemia), and the lack of symptoms.
Akira Shimatsu, Naoki Hattori
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Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview [PDF]
Case Reports in Endocrinology, 2013 Background. Macroprolactin, the high-molecular prolactin isoform, is considered to be an inactive in vivo product with extrapituitary origin. Patients with macroprolactinemia are usually asymptomatic, with negative pituitary imaging. Based on these data,
Atanaska Elenkova +5 more
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Detection of macroprolactinemia and molecular characterization of prolactin isoforms in blood samples of hyperprolactinemic women [PDF]
Journal of Medical Biochemistry, 2012 Prolactin (PRL) circulates in the blood in the form of monomeric prolactin, dimeric prolactin and macroprolactin. Macroprolactin is a common cause of hyperprolactinemia.
Rajinder Chawla +3 more
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Evaluation of Clinical Features of Female Patients with Macroprolactinemia
Endocrinology Research and Practice, 2011 Aim: Macroprolactin is a high-molecular-weight form of prolactin. It has been suggested that macroprolactin has no clinical importance because of its decreased or limited bioactivity. Although screening for macroprolactinemia is recommended especially in
Alev Eroğlu Altınova +5 more
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Response of Macroprolactinemia to Dopamine Agonists
Endocrinology Research and Practice, 2008 Macroprolactinemia, defined as hyperprolactinemia with a predominance of the big big prolactin (macroprolactin) isoform, is considered idiopathic and poorly symptomatic. Although macroprolactinemia has been considered to be a cause of apparent resistance
Gonca Tamer +3 more
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Transient Hyperprolactinemia Associated With Semaglutide in a Patient With Hashimoto's Thyroiditis. [PDF]
Case Rep MedSemaglutide, a glucagon‐like peptide‐1 (GLP‐1) receptor agonist, is widely used for weight management and glycemic control. While its metabolic and gastrointestinal effects are well characterized, its potential influence on pituitary function remains underexplored.
Guimarães GNF.
europepmc +2 more sources