Macroprolactinemia: A Mini-Review and Update on Clinical Practice [PDF]
F&S Reports, 2023 Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine G Koniares +2 more
exaly +5 more sources
Macroprolactinemia: A New Cause of Hyperprolactinemia
Journal of Pharmacological Sciences, 2003 Hyperprolactinemia is not only seen in pregnancy but also in several pathological conditions such as prolactin (PRL) secreting pituitary adenoma (prolactinoma), intracranial tumors compressing the pituitary stalk or hypothalamus, and PRL stimulative ...
Naoki Hattori
exaly +7 more sources
Laboratory and Clinical Significance of Macroprolactinemia in Women With Hyperprolactinemia [PDF]
Taiwanese Journal of Obstetrics and Gynecology, 2017 The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum +2 more
exaly +8 more sources
Clinical Characterization of Patients With Macroprolactinemia and Monomeric Hyperprolactinemia
Kaohsiung Journal of Medical Sciences, 2011 Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can +2 more
exaly +7 more sources
Macroprolactinemia in patients with hyperprolactinemia: an experience from a single tertiary center [PDF]
The Pan African Medical Journal, 2020 Macroprolactinemia frequently causes misdiagnosis, unnecessary investigation and inappropriate treatment in hyperprolactinemic patients. Aim of this study is to investigate the prevalence and clinical characteristics of Thai patients with ...
Phronpan Chutpiboonwat +5 more
doaj +3 more sources
The Effect of Metformin on Pituitary Function in Postmenopausal Women with Subclinical Hypothyroidism and Macroprolactinemia: A Single-Center Prospective Case–Control Study [PDF]
PharmaceuticalsBackground/Objectives: Metformin inhibits secretory function of overactive thyrotrophs, gonadotrophs, and lactotrophs. The clinical significance of an excess of high-molecular-weight prolactin (macroprolactinemia) remains unclear.
Robert Krysiak +3 more
doaj +3 more sources
Mild hyperprolactinemia in women with polycystic ovary syndrome. Insights from a large cross-sectional study [PDF]
Journal of Clinical & Translational EndocrinologyBackground: Hyperprolactinemia is an exclusion criterion for polycystic ovary syndrome (PCOS), albeit PCOS itself is argued to induce mild hyperprolactinemia.
Manuel Luque-Ramírez +6 more
doaj +3 more sources
Establishment of reference intervals of monomeric prolactin to identify macroprolactinemia in Chinese patients with increased total prolactin [PDF]
BMC Endocrine Disorders, 2021 Background Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients using monomeric prolactin ...
Yao Hu +8 more
doaj +2 more sources
Position statement on macroprolactinemia from the Department of Neuroendocrinology of the Brazilian Society of Endocrinology and Metabolism (SBEM) and the Brazilian Society of Clinical Pathology/Laboratory Medicine (SBPC/ML) [PDF]
Archives of Endocrinology and MetabolismMeasurement of serum prolactin levels is a common practice in clinical settings, particularly among women of reproductive age. In cases of hyperprolactinemia, identifying macroprolactinemia can help prevent unnecessary investigation and inappropriate ...
Andrea Glezer +10 more
doaj +2 more sources
Comparison of urinary prolactin and serum/urine prolactin ratio in hyperprolactinemic and macroprolactinemic patients [PDF]
BMC Endocrine DisordersBackground Biologically, the monomeric form of prolactin is the most active. In measurement methods, all forms of prolactin are included in the assay; therefore, the presence of macroprolactin, causes a false increase in prolactin and misdiagnosis of ...
Behnam Ein-Mozaffari +8 more
doaj +2 more sources