Results 21 to 30 of about 483 (156)

Response of Macroprolactinemia to Dopamine Agonists

Endocrinology Research and Practice, 2008
Macroprolactinemia, defined as hyperprolactinemia with a predominance of the big big prolactin (macroprolactin) isoform, is considered idiopathic and poorly symptomatic. Although macroprolactinemia has been considered to be a cause of apparent resistance
Gonca Tamer, Ayşegül Telci, Ferihan Aral, Faruk Alagöl   +3 more
doaj   +3 more sources

Macroprolactinemia and Empty Sella Syndrome

The Pan African Medical Journal, 2017
Macroprolactinemia is a polymeric form of prolactin-release, causing mildly symptomatic clinical pictures. The former can be isolated or associated with other causes of hyperprolactinemia. The association with an empty sella syndrome is rare. We report a
Ach Taieb, Kacem Njah Maha, Yosra Hasni El Abed, Amel Maaroufi Beizig, Molka Chaieb Chadli, Koussay Ach   +5 more
doaj   +3 more sources

Persistent idiopathic prolactin elevation merits macroprolactin estimation: A case report and review of literature [PDF]

Journal of Human Reproductive Sciences, 2021
The prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%–17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
Krishnaprabha Gautam, Kripa Elizabeth Cherian, Arun Jose, T K Aleyamma, Nitin Kapoor, Thomas Vizhalil Paul   +5 more
doaj   +2 more sources

Evaluation of Clinical Features of Female Patients with Macroprolactinemia

Endocrinology Research and Practice, 2011
Aim: Macroprolactin is a high-molecular-weight form of prolactin. It has been suggested that macroprolactin has no clinical importance because of its decreased or limited bioactivity. Although screening for macroprolactinemia is recommended especially in
Alev Eroğlu Altınova, Müjde Aktürk, Göksun Ayvaz, Sevim Güllü, Metin Arslan, Leyla Mollamahmutoğlu   +5 more
doaj   +3 more sources

Usefulness of prolactin levels in predicting the etiology of hyperprolactinemia in a cohort of 770 patients [PDF]

Archives of Endocrinology and Metabolism
Objective Determining the etiology of hyperprolactinemia is fundamental for selecting the most appropriate treatment strategy. The aim of this study was to evaluate the usefulness and accuracy of prolactin levels in predicting the etiology of ...
Lucio Vilar, Clarice Freitas Vilar, Ruy Lyra, Luciano Albuquerque, Ana Carolina Thé Garrido, Patrícia Sampaio Gadelha, Erik Trovão Diniz, Marcos Almeida, Lucia Helena Cordeiro, Erico Higino de Carvalho, Ana Teresa Bezerra de Melo, Karoline Matias Medeiros, Gabriel Rodrigues de Assis Ferreira, José Coelho Mororó Neto, Daniela Zago Ximenes, Camila Ribeiro Coutinho Madruga, Rosália de Oliveira Nunes, Yanna Queiroz Pereira de Sá, Luciana Ansaneli Naves   +18 more
doaj   +2 more sources

Macrohormones in endocrinology: prevalence, clinical impact, and diagnostic approaches [PDF]

Frontiers in Endocrinology
Macrohormones also called macromolecules or macrocomplexes are described as an antigen-antibody complex, consisting of monomeric hormones bound to immunoglobulins. These molecules exhibit minimal or no biological activity.
Agata Bronisławska, Olivia Cyran-Stańczak, Olivia Cyran-Stańczak, Robert Bronisławski, Alicja Solecka, Agata Berlińska, Agata Berlińska, Renata Świątkowska-Stodulska, Renata Świątkowska-Stodulska, Jarosław Piotr Jendrzejewski, Jarosław Piotr Jendrzejewski   +10 more
doaj   +2 more sources

Assessment of macroprolactinemia inpatients with prolactinoma

Turkish Journal of Biochemistry, 2017
Abstract Purpose Macroprolactin, the high-molecular mass prolactin isoform, is considered to be an inactive product with extrapituitary origin. Although macroprolactinemia is considered a benign condition, there is evidence of overlapping clinical features among patients with hyperprolactinemia.
Sema Ciftci Dogansen, Gulsah Yenidunya Yalin, Sema Yarman   +2 more
openaire   +2 more sources

The importance of routine screening for macroprolactin in symptomatic patients with idiopathic hyperprolactinemia [PDF]

Anais da Faculdade de Medicina de Olinda, 2018
Objective: To evaluate the importance of screening for macroprolactin in symptomatic patients with apparent idiopathic hyperprolactinemia. Methods: During 20 months, the prevalence of macroprolactinemia was evaluated among consecutive symptomatic female
Lucio Vilar, Clarice Vilar, José Luciano Albuquerque, Ana Carolina Thé, Patricia Gadelha, Thaíse Borges, Izabela Cardoso, Liana Ferreira, Icaro Sampaio, Maíra Melo, Erik Diniz, Ruy Lyra   +11 more
doaj   +2 more sources

The importance of measuring macroprolactin in the differential diagnosis of hyperprolactinemic patients

Kaohsiung Journal of Medical Sciences, 2012
This study investigated the differences in clinical and laboratory features as well as treatment response in 70 outpatients with macroprolactinemia and monomeric hyperprolactinemia treated with dopamine agonists.
Chih-Chin Lu, Ching-Jung Hsieh
doaj   +2 more sources

The Effect of Macroprolactinemia on Gonadotropin Secretion

The Endocrinologist, 2007
Objectives: Hyperprolactinemia due to monomeric prolactin (m-PRL), is associated with suppression of gonadotropin secretion and gonadal activity. Macroprolactin is thought to be a biologically inactive form of prolactin that has no effects on gonadotropin secretion.
Gonca Tamer, Aysegül Telci, Ferihan Aral, Sema Yarman, Nese Özbey, Harika Boztepe, Faruk Alagöl   +6 more
openaire   +2 more sources