Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia [PDF]
Taiwanese Journal of Obstetrics and Gynecology, 2017 The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum, Slavko Orešković
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Macroprolactinemia: a New Cause of Hyperprolactinemia
Journal of Pharmacological Sciences, 2003 Hyperprolactinemia is not only seen in pregnancy but also in several pathological conditions such as prolactin (PRL) secreting pituitary adenoma (prolactinoma), intracranial tumors compressing the pituitary stalk or hypothalamus, and PRL stimulative ...
Naoki Hattori
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Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia
Kaohsiung Journal of Medical Sciences, 2011 Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can +2 more
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Macroprolactinemia in a Patient with Invasive Macroprolactinoma: A Case Report and Minireview [PDF]
Case Reports in Endocrinology, 2013 Background. Macroprolactin, the high-molecular prolactin isoform, is considered to be an inactive in vivo product with extrapituitary origin. Patients with macroprolactinemia are usually asymptomatic, with negative pituitary imaging. Based on these data,
Atanaska Elenkova +5 more
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The Correlation Between DRD2 and COMT Gene Polymorphisms, HPT and HPG Axes Functions, and Antipsychotic Drug-Induced Hyperprolactinemia and Macroprolactinemia [PDF]
Neuropsychiatric Disease and TreatmentZhenhua Wang,1 Jing Li,2 Haizhi Chen,1 Haiying Jin,1 Shiliang Wang,1 Xuqiang Hu1 1Department of Psychiatry, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, People’s Republic of China; 2Center for Disease ...
Wang Z +5 more
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Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia
The Turkish Journal of Pediatrics, 2006 Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL.
Filiz Tütüncüler +3 more
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Mild hyperprolactinemia in women with polycystic ovary syndrome. Insights from a large cross-sectional study [PDF]
Journal of Clinical & Translational EndocrinologyBackground: Hyperprolactinemia is an exclusion criterion for polycystic ovary syndrome (PCOS), albeit PCOS itself is argued to induce mild hyperprolactinemia.
Manuel Luque-Ramírez +6 more
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Response of Macroprolactinemia to Dopamine Agonists
Endocrinology Research and Practice, 2008 Macroprolactinemia, defined as hyperprolactinemia with a predominance of the big big prolactin (macroprolactin) isoform, is considered idiopathic and poorly symptomatic. Although macroprolactinemia has been considered to be a cause of apparent resistance
Gonca Tamer +3 more
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Detection of macroprolactinemia and molecular characterization of prolactin isoforms in blood samples of hyperprolactinemic women [PDF]
Journal of Medical Biochemistry, 2012 Prolactin (PRL) circulates in the blood in the form of monomeric prolactin, dimeric prolactin and macroprolactin. Macroprolactin is a common cause of hyperprolactinemia.
Rajinder Chawla +3 more
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Persistent idiopathic prolactin elevation merits macroprolactin estimation: A case report and review of literature [PDF]
Journal of Human Reproductive Sciences, 2021 The prevalence of hyperprolactinemia ranges from about 0.4% in an unselected adult population to as high as 9%–17% in women with reproductive disorders. It may cause infertility in about 11% of the oligospermic males.
Krishnaprabha Gautam +5 more
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