Results 41 to 50 of about 990 (199)
Prevalence of Macroprolactinaemia by Polyethylene Glycol Precipitation Method: A Cross-sectional Study [PDF]
National Journal of Laboratory Medicine, 2021 Introduction: Macroprolactin, an immunoreactive molecule resulting from association of monomeric Prolactin (mPRL) and immunoglobulin G is a significant cause of misdiagnosis, unnecessary radiological investigation and treatment for ...
RAGHUNATH BHATTACHARYYA +4 more
doaj +1 more source
Proceedings of Singapore Healthcare, 2022 Prolactin, a hormone secreted by the anterior pituitary, exists in three major forms in circulation. The macroprolactin form is biologically inactive but contributes to elevated serum prolactin concentrations.
Pallavi Chincholkar +2 more
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Journal of Clinical Laboratory Analysis, Volume 37, Issue 5, March 2023., 2023 Gel filtration chromatogram of proved macroamylase in two patients serum. Macroamylase can occur in sera of healthy people without any symptoms and knowledge of macrocomplexes can help avoid diagnostic errors in the differential diagnosis as well as reduce useless invasive and expensive examinations of patients.
Jitka Čásenská +3 more
wiley +1 more source
Case Reports in Endocrinology, Volume 2021, Issue 1, 2021., 2021 Prolactin‐secreting leiomyomas are rare, with only eight cases reported in the literature. This case describes a 37‐year‐old female with hyperprolactinaemia (1846 mIU/L; 85–500 mIU/L) refractory to cabergoline causing infertility and galactorrhea. MRI pituitary was normal. The patient had a known enlarging uterine leiomyoma on serial pelvic ultrasounds
Lucinda Barry +4 more
wiley +1 more source
Macroprolactinemia: a mini-review and update on clinical practice
F&S Reports, 2023 Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D. +4 more
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Acta Médica Portuguesa, 2011 Up to 95% of adult serum prolactin is monomeric prolactin with a molecular weight of 23 kDa. Macroprolactin is a prolactin-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating prolactin.
Andreia Veloza, Susana Prazeres
doaj +1 more source
Journal of Clinical Laboratory Analysis, Volume 34, Issue 11, November 2020., 2020 To evaluate the prevalence of associated autoantibodies, as well as the IgG subclass distributions in the patients suspected for macroprolactinemia, totally 317 patients with elevated prolactin were recruited for the initial screening with the polyethylene glycol precipitation assay.
Chao Yu +12 more
wiley +1 more source
Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk
International Journal of Endocrinology, Volume 2020, Issue 1, 2020., 2020 CKD has a high prevalence worldwide, mainly due to its main etiologies—diabetes and hypertension. It has high cardiovascular morbidity and mortality, with traditional risk factors such as atherosclerosis, hypertension, diabetes, smoking, and left ventricular hypertrophy being common.
Marclébio Dourado +4 more
wiley +1 more source
Dubai Diabetes and Endocrinology Journal, 2021 Objectives: Macroprolactin (macroPRL) excess is an important cause of hyperprolactinemia. Several prolactin assays have high reactivity to macroPRL. However, macroPRL screening is not routinely performed in many labs.
Abdulla Al Nuaimi +4 more
doaj +1 more source
Prevalence of Macroprolactin in Hyperprolactinemic patients receiving Anti-psychotics
medRxiv, 2021 Background: Prolactin (PRL) hormone circulates in the blood in three forms, mono-prolactin which constitutes 85 % of prolactin in healthy and hyperprolactinemia conditions, a dimeric prolactin (big PRL) and polymeric PRL (big-big prolactin or ...
L. Al Wasify +2 more
semanticscholar +1 more source