Results 61 to 70 of about 580 (145)
The lmportance of Macroprolactin in the Differential Diagnosis of Hyperprolactinemia [PDF]
The aim of this study: To evaluate the significance of macroprolactin for differential diagnosis of hyperprolactinemia. Objectives of work: 1. To estimate the frequency of macroprolactinaemia in patients with hyperprolactinemia. 2.
Jašmontaitė, Vaida
core
Objective: It has been shown that macroprolactin (MaPRL) is biologically inactive because the large molecular size of this complex prevents its crossing through the capillary blood barrier and reaching target cells. The aim of this study is to detect the
Khan, Aysha Habib, Sherazi, Noreen
core +2 more sources
Background The so called “big-big” prolactin (Prl), also known as macroprolactin is formed by Prl-immunoglobulin (Prl-IgG) complexes and may cause elevation of serum Prl concentrations measured by standard assays, potentially leading to unnecessary ...
Lewandowski Krzysztof C +3 more
doaj +1 more source
Importance of macroprolactinemia in hyperprolactinemia [PDF]
Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G.
Pavičić-Baldani, Dinka +6 more
core +1 more source
This study investigated the differences in clinical and laboratory features as well as treatment response in 70 outpatients with macroprolactinemia and monomeric hyperprolactinemia treated with dopamine agonists.
Chih-Chin Lu, Ching-Jung Hsieh
doaj +1 more source
20.500.12530/87858Prolactin measurement is very common in standard clinical practice. It is indicated not only in the study of pituitary adenomas, but also when there are problems with fertility, decreased libido, or menstrual disorders, among other ...
Esteban Salán, Margarita +14 more
core +1 more source
Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia
Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can +4 more
doaj +1 more source
A possible cause of the variable detectability of macroprolactin by different immunoassay systems
Background: Macroprolactinaemia is a major cause of hyperprolactinaemia. The detectability of macroprolactin varies widely among different immunoassay systems, but the causes are not fully known.
Hattori, Naoki +2 more
core +1 more source
Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia
Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL.
Filiz Tütüncüler +3 more
doaj +1 more source
Prolactinomas are the most common pituitary adenomas (approximately 40% of cases), and they represent an important cause of hypogonadism and infertility in both sexes.
Lucio Vilar +24 more
doaj +1 more source

