Results 61 to 70 of about 580 (145)

The lmportance of Macroprolactin in the Differential Diagnosis of Hyperprolactinemia [PDF]

open access: yes, 2020
The aim of this study: To evaluate the significance of macroprolactin for differential diagnosis of hyperprolactinemia. Objectives of work: 1. To estimate the frequency of macroprolactinaemia in patients with hyperprolactinemia. 2.
Jašmontaitė, Vaida
core  

Post-polyethylene glycol (PEG) treated prolactin levels for the detection of macroprolactin - time to change

open access: yes, 2014
Objective: It has been shown that macroprolactin (MaPRL) is biologically inactive because the large molecular size of this complex prevents its crossing through the capillary blood barrier and reaching target cells. The aim of this study is to detect the
Khan, Aysha Habib, Sherazi, Noreen
core   +2 more sources

Prevalence of macroprolactinaemia in regularly menstruating women with non-toxic goitre or autoimmune thyroid disease

open access: yesThyroid Research, 2012
Background The so called “big-big” prolactin (Prl), also known as macroprolactin is formed by Prl-immunoglobulin (Prl-IgG) complexes and may cause elevation of serum Prl concentrations measured by standard assays, potentially leading to unnecessary ...
Lewandowski Krzysztof C   +3 more
doaj   +1 more source

Importance of macroprolactinemia in hyperprolactinemia [PDF]

open access: yes, 2014
Macroprolactin is an antigen-antibody complex of higher molecular mass than prolactin (>150kDa), consisting of monomeric prolactin and immunoglobulin G.
Pavičić-Baldani, Dinka   +6 more
core   +1 more source

The importance of measuring macroprolactin in the differential diagnosis of hyperprolactinemic patients

open access: yesKaohsiung Journal of Medical Sciences, 2012
This study investigated the differences in clinical and laboratory features as well as treatment response in 70 outpatients with macroprolactinemia and monomeric hyperprolactinemia treated with dopamine agonists.
Chih-Chin Lu, Ching-Jung Hsieh
doaj   +1 more source

Macroprolactina: del laboratorio a la práctica clínica. Recomendaciones del grupo de trabajo de laboratorio de la SEEN y de la comisión de hormonas de la SEQCML sobre la medición e informe del resultado de la macroprolactina.

open access: yes, 2021
20.500.12530/87858Prolactin measurement is very common in standard clinical practice. It is indicated not only in the study of pituitary adenomas, but also when there are problems with fertility, decreased libido, or menstrual disorders, among other ...
Esteban Salán, Margarita   +14 more
core   +1 more source

Clinical characterization of patients with macroprolactinemia and monomeric hyperprolactinemia

open access: yesKaohsiung Journal of Medical Sciences, 2011
Macroprolactinemia is often a cause of misdiagnosis, unnecessary expensive investigation, and unsuitable treatment. The aim of the present study was to investigate the clinical findings and the concentrations of macroprolactin in patients with ...
Murat Can   +4 more
doaj   +1 more source

A possible cause of the variable detectability of macroprolactin by different immunoassay systems

open access: yes
Background: Macroprolactinaemia is a major cause of hyperprolactinaemia. The detectability of macroprolactin varies widely among different immunoassay systems, but the causes are not fully known.
Hattori, Naoki   +2 more
core   +1 more source

Macroprolactinemia in childhood and adolescence: a cause of hyperprolactinemia

open access: yesThe Turkish Journal of Pediatrics, 2006
Human prolactin consists of multiple forms of different sizes including three major prolactin (PRL) species, termed as little, big, and big-big PRL.
Filiz Tütüncüler   +3 more
doaj   +1 more source

Controversial issues in the management of hyperprolactinemia and prolactinomas – An overview by the Neuroendocrinology Department of the Brazilian Society of Endocrinology and Metabolism

open access: yesArchives of Endocrinology and Metabolism
Prolactinomas are the most common pituitary adenomas (approximately 40% of cases), and they represent an important cause of hypogonadism and infertility in both sexes.
Lucio Vilar   +24 more
doaj   +1 more source

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