Results 51 to 60 of about 580 (145)

Using Polyethylene Glycol Precipitation to Differentiate between Macroprolactinemia and Hyperprolactinemia

open access: yesSiriraj Medical Journal, 2014
Hyperprolactinemia is a common endocrine disorder which clinically manifestats in reproductive period and presents with hypogonadism, galactorrhea and symptoms related to tumor mass effects.
Chongdee Dangrat
doaj  

Laboratory Aspects of Hyperprolactinemia Diagnosis

open access: yesMìžnarodnij Endokrinologìčnij Žurnal, 2015
The paper presents the modern laboratory aspects of diagnosing hyperprolactinemia and monitoring the effectiveness of treatment according to the Diagnosis and Treatment of Hyperprolactinemia: An Endocrine Society Clinical Practice Guideline 2011.
O.V. Rykova
doaj   +1 more source

Premature pubarche as a first presentation of pituitary macroprolactinoma

open access: yesJournal of Research in Medical Sciences, 2020
Prolactinoma is a rare tumor of childhood. Clinical presentations of prolactinoma include amenorrhea, delayed puberty, and galactorrhea. For the first time, in this case, elevated prolactin levels were associated with unexpected premature pubarche.
Fatemeh Tabatabaei   +5 more
doaj   +1 more source

Macroprolactin does not contribute to elevated levels of prolactin in patients on renal replacement therapy

open access: yes, 2005
Objective Three molecular forms of PRL with molecular weights of 23, 50-60 and > 100 kDa have been defined. The high-molecular-weight forms are called macroprolactin.
ŞİRİKÇİ, ÖNDER, YAVUZ, DİLEK
core   +1 more source

Serum prolactin revisited: parametric reference intervals and cross platform evaluation of polyethylene glycol precipitation-based methods for discrimination between hyperprolactinemia and macroprolactinemia [PDF]

open access: yes, 2017
Background:Hyperprolactinemia diagnosis and treatment is often compromised by the presence of biologically inactive and clinically irrelevant higher-molecular-weight complexes of prolactin, macroprolactin.
Susanne Møller Pedersen   +3 more
core   +1 more source

Clinical Significance of Elevated Macroprolactin Levels in Patients with Hyperprolactinemia. Case report

open access: yes, 2017
Introduction: Hyperprolactinemia is the most common abnormality of the hypothalamic-pituitary axis and is the most frequent manifestation of functional pituitary adenomas.
Kerekovska, Velina, Zlatanova, Evelina
core   +1 more source

Optimizing laboratory defined macroprolactin algorithm [PDF]

open access: yes, 2019
Introduction: Macroprolactinaemia is a well-known analytical problem in diagnostics of hyperprolactinaemia usually detected with polyethylene glycol (PEG) precipitation method.
Zec, Ivana   +3 more
core   +1 more source

Macroprolactin; a Frequent Cause of Misdiagnosed Hyperprolactinemia in Clinical Practice

open access: yes, 2020
Introduction: Macroprolactin is a significant cause of misdiagnosis, unnecessary investigation, and inappropriate treatment in patients with hyperprolactinemia.
R Vaishya, R Gupta, S Arora
core  

Macroprolactinaemia in a 33-year old premenopausal Nigerian woman: a case report [PDF]

open access: yes, 2017
Background: Macroprolactin is a 150-170kDa heteropolymeric complex of monomeric prolactin and immunoglobulin G (IgG) that contributes less than 1% of circulating prolactin concentration in plasma. It exerts little or no biological action in vivo.
Okpara, H.C.   +4 more
core   +1 more source

Macroprolactin - prevalence, diagnostic methods and clinical significance [PDF]

open access: yes, 2009
Macroprolactin (MaPRL) is a high molecular mass variant of prolactin (PRL), which usually consists of a monomeric PRL and an immunoglobulin G molecule.
Beda, Karolina, Winczyk, Katarzyna
core  

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