Results 21 to 30 of about 580 (145)
Thermal degradation of polyethylene glycol 6000 and its effect on the assay of macroprolactin [PDF]
Study of the effectiveness of partially degraded polyethylene glycol 6000 (PEG) as a precipitant for macroprolactin. PEG was heated to 63 °C in air for up to 20 days and its effectiveness assessed as a precipitant for sera containing normal prolactin or ...
Boughen, Louise +2 more
core +4 more sources
Prolactin, a hormone secreted by the anterior pituitary, exists in three major forms in circulation. The macroprolactin form is biologically inactive but contributes to elevated serum prolactin concentrations.
Pallavi Chincholkar +2 more
doaj +1 more source
Gel filtration chromatogram of proved macroamylase in two patients serum. Macroamylase can occur in sera of healthy people without any symptoms and knowledge of macrocomplexes can help avoid diagnostic errors in the differential diagnosis as well as reduce useless invasive and expensive examinations of patients.
Jitka Čásenská +3 more
wiley +1 more source
Prolactin‐secreting leiomyomas are rare, with only eight cases reported in the literature. This case describes a 37‐year‐old female with hyperprolactinaemia (1846 mIU/L; 85–500 mIU/L) refractory to cabergoline causing infertility and galactorrhea. MRI pituitary was normal. The patient had a known enlarging uterine leiomyoma on serial pelvic ultrasounds
Lucinda Barry +4 more
wiley +1 more source
Antipsychotics-induced hyperprolactinemia and screening for macroprolactin [PDF]
Introduction: High prolactin (PRL) concentrations are found in laboratory test results of patients on majority of antipsychotic drugs. Prevalence rates and degrees of severity of hyperprolactinemia (HPRL) based on PRL concentration may depend on the ...
Ruljancic, Nedjeljka +15 more
core +1 more source
Macroprolactinemia: a mini-review and update on clinical practice
Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D. +4 more
doaj +1 more source
Up to 95% of adult serum prolactin is monomeric prolactin with a molecular weight of 23 kDa. Macroprolactin is a prolactin-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating prolactin.
Andreia Veloza, Susana Prazeres
doaj +1 more source
Comparison of multiple methods for identification of hyperprolactinemia in the presence of macroprolactin [PDF]
Macroprolactin is a large, heterogeneous form of prolactin with limited bioavailability. Detection of macroprolactin by different immunoassays varies widely.
Sharpless, Julie L. +2 more
core +1 more source
To evaluate the prevalence of associated autoantibodies, as well as the IgG subclass distributions in the patients suspected for macroprolactinemia, totally 317 patients with elevated prolactin were recruited for the initial screening with the polyethylene glycol precipitation assay.
Chao Yu +12 more
wiley +1 more source
Existem fortes evidências sobre a influência dos hormônios sexuais na imunidade e na apresentação de doenças auto-imunes, entre elas o lúpus eritematoso sistêmico (LES).
Fabiane Tiskievicz +3 more
doaj +1 more source

