Results 21 to 30 of about 990 (199)

SUN-042 Circulating macroprolactin a cause for discrepancy among hyperprolactinemic patients and is method dependent. [PDF]

J Endocr Soc
Disclosure: I.A. Hashim: None. K. Fankhauser: None. E. Abraham: None. Introduction: Circulating human prolactin is known to exhibit molecular heterogeneity the clinical significance of which remains unknown.
Ibrahim A Hashim, Kimberly Fankhauser, E. Abraham   +2 more
europepmc   +2 more sources

Prevalence of Macroprolactinaemia in Women with Hyperprolactinaemia: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Macroprolactinaemia causes asymptomatic hyperprolactinaemia in many patients which leads to misdiagnosis, inappropriate investigation and needless treatment in these patients.
Flavia Almeida, Alap Christy, Varsha Birla, Raj Jatale, Kirti Chadha   +4 more
doaj   +2 more sources

Prolactina e macroprolactina no lúpus eritematoso sistêmico (LES) Prolactin and macroprolactin in systemic lupus erythematosus (SLE)

Revista Brasileira de Reumatologia, 2005
Existem fortes evidências sobre a influência dos hormônios sexuais na imunidade e na apresentação de doenças auto-imunes, entre elas o lúpus eritematoso sistêmico (LES).
Fabiane Tiskievicz, Elaine Sangalli Mallmann, Ricardo Machado Xavier, João Carlos Tavares Brenol   +3 more
doaj   +2 more sources

HARMONISATION OF MACROPROLACTIN REPORTING

Journal of the ASEAN Federation of Endocrine Societies
INTRODUCTION/BACKGROUNDThe post-analytical phase is the last phase of the total testing process and it is an important step since it maximises the quality and effectiveness of laboratory information.
P. Sthaneshwar, S. Thambiah, Jeyakantha Ratnasingam3   +2 more
semanticscholar   +2 more sources

Macroprolactinemia: Diagnostic, Clinical, and Pathogenic Significance [PDF]

Clinical and Developmental Immunology, 2012
Macroprolactinemia is characterized by a large molecular mass of PRL (macroprolactin) as the main molecular form of PRL in sera, the frequent elevation of serum PRL (hyperprolactinemia), and the lack of symptoms.
Akira Shimatsu, Naoki Hattori
doaj   +2 more sources

Comparison of multiple methods for identification of hyperprolactinemia in the presence of macroprolactin [PDF]

Clinica Chimica Acta, 2010
Macroprolactin is a large, heterogeneous form of prolactin with limited bioavailability. Detection of macroprolactin by different immunoassays varies widely. The objectives of this study were to determine the immunoreactivity of macroprolactin by the Ortho Clinical Diagnostics Vitros ECi prolactin immunoassay, establish the most effective method for ...
Christopher R, McCudden, Julie L, Sharpless, David G, Grenache   +2 more
openaire   +4 more sources

Establishment of reference intervals of monomeric prolactin to identify macroprolactinemia in Chinese patients with increased total prolactin [PDF]

BMC Endocrine Disorders, 2021
Background Macroprolactin is responsible for pseudohyperprolactinemia and is a common pitfall of the prolactin immunoassay. We aimed to determine the frequency of macroprolactinemia in Chinese hyperprolactinemic patients using monomeric prolactin ...
Yao Hu, Jiajin Ni, Buyue Zhang, Wei Cheng, Huating Zhang, Hongying Ye, Lijin Ji, Bin Lu, Ming Guan   +8 more
doaj   +2 more sources

Laboratory and clinical significance of macroprolactinemia in women with hyperprolactinemia [PDF]

Taiwanese Journal of Obstetrics & Gynecology, 2017
The role of macroprolactinemia in women with hyperprolactinemia is currently controversial and can lead to clinical dilemmas, depending upon the origin of macroprolactin, the presence of hyperprolactinemic symptoms and monomeric prolactin (PRL) levels ...
Miro Kasum, Slavko Orešković, Ermin Čehić, Martina Šunj, Albert Lila, Emina Ejubović   +5 more
doaj   +2 more sources

The Correlation Between DRD2 and COMT Gene Polymorphisms, HPT and HPG Axes Functions, and Antipsychotic Drug-Induced Hyperprolactinemia and Macroprolactinemia [PDF]

Neuropsychiatric Disease and Treatment
Zhenhua Wang,1 Jing Li,2 Haizhi Chen,1 Haiying Jin,1 Shiliang Wang,1 Xuqiang Hu1 1Department of Psychiatry, Huzhou Third Municipal Hospital, the Affiliated Hospital of Huzhou University, Huzhou, Zhejiang, People’s Republic of China; 2Center for Disease ...
Wang Z, Li J, Chen H, Jin H, Wang S, Hu X   +5 more
doaj   +2 more sources

Macroprolactin: what is it and what is its importance?

International Journal of Clinical Practice, 2006
Monomeric prolactin (PRL) of molecular weight 23 kDa constitutes up to 95% of adult serum PRL. Macroprolactin is a large antigen-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating PRL. Thus, in most cases, hyperprolactinaemia is usually a result of high levels of monomeric PRL, which may be due to ...
H Sadideen
exaly   +4 more sources