Results 21 to 30 of about 580 (145)

Thermal degradation of polyethylene glycol 6000 and its effect on the assay of macroprolactin [PDF]

open access: yes, 2010
Study of the effectiveness of partially degraded polyethylene glycol 6000 (PEG) as a precipitant for macroprolactin. PEG was heated to 63 °C in air for up to 20 days and its effectiveness assessed as a precipitant for sera containing normal prolactin or ...
Boughen, Louise   +2 more
core   +4 more sources

Gender-specific reference intervals for serum prolactin concentrations before and after precipitation by polyethylene glycol

open access: yesProceedings of Singapore Healthcare, 2022
Prolactin, a hormone secreted by the anterior pituitary, exists in three major forms in circulation. The macroprolactin form is biologically inactive but contributes to elevated serum prolactin concentrations.
Pallavi Chincholkar   +2 more
doaj   +1 more source

Significant elevations of serum amylase caused by macroamylase: Case reports and detection possibilities

open access: yesJournal of Clinical Laboratory Analysis, Volume 37, Issue 5, March 2023., 2023
Gel filtration chromatogram of proved macroamylase in two patients serum. Macroamylase can occur in sera of healthy people without any symptoms and knowledge of macrocomplexes can help avoid diagnostic errors in the differential diagnosis as well as reduce useless invasive and expensive examinations of patients.
Jitka Čásenská   +3 more
wiley   +1 more source

Prolactin‐Secreting Leiomyoma Causing Hyperprolactinaemia Unresponsive to Dopamine Agonist Therapy and Resolution following Myomectomy

open access: yesCase Reports in Endocrinology, Volume 2021, Issue 1, 2021., 2021
Prolactin‐secreting leiomyomas are rare, with only eight cases reported in the literature. This case describes a 37‐year‐old female with hyperprolactinaemia (1846 mIU/L; 85–500 mIU/L) refractory to cabergoline causing infertility and galactorrhea. MRI pituitary was normal. The patient had a known enlarging uterine leiomyoma on serial pelvic ultrasounds
Lucinda Barry   +4 more
wiley   +1 more source

Antipsychotics-induced hyperprolactinemia and screening for macroprolactin [PDF]

open access: yes, 2021
Introduction: High prolactin (PRL) concentrations are found in laboratory test results of patients on majority of antipsychotic drugs. Prevalence rates and degrees of severity of hyperprolactinemia (HPRL) based on PRL concentration may depend on the ...
Ruljancic, Nedjeljka   +15 more
core   +1 more source

Macroprolactinemia: a mini-review and update on clinical practice

open access: yesF&S Reports, 2023
Hyperprolactinemia is common among infertile patients, with up to 15%–20% of women with oligomenorrhea having hyperprolactinemia. Suppression of the hypothalamic-pituitary-gonadal axis via inhibition of pulsatile gonadotropin releasing hormone because of
Katherine Koniares, M.D.   +4 more
doaj   +1 more source

Prolactina e o laboratório.

open access: yesActa Médica Portuguesa, 2011
Up to 95% of adult serum prolactin is monomeric prolactin with a molecular weight of 23 kDa. Macroprolactin is a prolactin-antibody complex of molecular weight greater than 100 kDa and constitutes less than 1% of circulating prolactin.
Andreia Veloza, Susana Prazeres
doaj   +1 more source

Comparison of multiple methods for identification of hyperprolactinemia in the presence of macroprolactin [PDF]

open access: yes, 2010
Macroprolactin is a large, heterogeneous form of prolactin with limited bioavailability. Detection of macroprolactin by different immunoassays varies widely.
Sharpless, Julie L.   +2 more
core   +1 more source

Evaluation of autoantibodies and immunoglobulin G subclasses in women with suspected macroprolactinemia

open access: yesJournal of Clinical Laboratory Analysis, Volume 34, Issue 11, November 2020., 2020
To evaluate the prevalence of associated autoantibodies, as well as the IgG subclass distributions in the patients suspected for macroprolactinemia, totally 317 patients with elevated prolactin were recruited for the initial screening with the polyethylene glycol precipitation assay.
Chao Yu   +12 more
wiley   +1 more source

Prolactina e macroprolactina no lúpus eritematoso sistêmico (LES) Prolactin and macroprolactin in systemic lupus erythematosus (SLE)

open access: yesRevista Brasileira de Reumatologia, 2005
Existem fortes evidências sobre a influência dos hormônios sexuais na imunidade e na apresentação de doenças auto-imunes, entre elas o lúpus eritematoso sistêmico (LES).
Fabiane Tiskievicz   +3 more
doaj   +1 more source

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