Results 91 to 100 of about 95,130 (338)

Bronchial thermoplasty : a new therapeutic option for the treatment of severe, uncontrolled asthma in adults [PDF]

, 2014
Bronchial thermoplasty is a young yet promising treatment for severe asthma whose benefit for long-term asthma control outweighs the short-term risk of deterioration and hospitalisation in the days following the treatment.
Alagha, Khuder, Aubier, Michel, Boulet, Louis Philippe, Brillet, Pierre Yves, Chanez, Pascal, Dombret, Marie-Christine, Joos, Guy, Laviolette, Michel, Louis, Renaud, Rochat, Thierry, Soccal, Paola   +10 more
core   +5 more sources

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, EarlyView.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Central Airway Carcinoid Tumorlets Following Resection of a Typical Carcinoid Tumor

Diagnostics
Pulmonary neuroendocrine proliferations and neoplasms represent a broad spectrum of diseases, ranging from neuroendocrine cell hyperplasia and tumorlets to carcinoid tumors.
Kyungsoo Bae, Kyung Nyeo Jeon, I Re Heo, Hyo Jung An, Dae Hyun Song   +4 more
doaj   +1 more source

Grossly and Microscopic Study of the Primary Bronchi and Lungs of Wood Pigeon (Columba palumbus)

Kufa Journal for Veterinary Medical Sciences, 2013
The present study included ten specimens of adult pigeon wood (Columba palumbus) collected from market of Al-Diwanyia city, divided the specimens into two groups five specimens for grossly study and five specimens for histological study.
Saffia Kareem Wally Alumeri, Nabeel Abd Murad Al-Mamoori, Abdulla aid Hadi Al-Bishtue   +2 more
doaj   +1 more source

The once-daily fixed-dose combination of olodaterol and tiotropium in the management of COPD : current evidence and future prospects [PDF]

, 2019
Long-acting bronchodilators are the cornerstone of pharmacologic treatment of chronic obstructive pulmonary disease (COPD). Spiolto (R) or Stiolto (R) is a fixed-dose combination (FDC) containing two long-acting bronchodilators, the long-acting ...
Brusselle, Guy, Derom, Eric, Joos, Guy
core   +1 more source

Inactivation of AXL in Cardiac Fibroblasts Alleviates Right Ventricular Remodeling in Pulmonary Hypertension

Advanced Science, EarlyView.
Pulmonary hypertension (PH) is a progressive condition with high morbidity and mortality, largely owing to right ventricular (RV) failure resulting from maladaptive remodeling. Our study provides strong evidence in support of a critical, detrimental role for AXL as a previously unrecognized determinant driving RV fibrotic pathology in PH.
Li‐Wei Wu, Min Chen, Chen‐Yu Jiang, Dai‐Ji Jiang, Xu Zhang, Xiao‐He Xu, Yi‐Wei Liu, Bei Feng, Lin‐Cai Ye, Yang‐Yang He, Xu Huang, Yi‐Chi Zhang, Xing‐Liang Zhou, Yi Shen, Tian‐Yu Liu, Li‐Jun Fu, Yi Yan, Hao Zhang   +17 more
wiley   +1 more source

Proposed treatment algorithms for dogs with chronic bronchitis associated with irreversible airway changes: bronchiectasis and/or bronchomalacia

Frontiers in Veterinary Science
Chronic bronchitis (CB) in dogs involves persistent inflammation of the bronchial walls and excessive mucus production within the airways, with or without bronchial infection, and may lead to degenerative airway changes such as bronchiectasis (BE) and ...
Aurélie Lyssens, Elodie Roels, Cécile Clercx, Frédéric Billen   +3 more
doaj   +1 more source

Risk factors for hospital admission with RSV bronchiolitis in England: a population-based birth cohort study. [PDF]

, 2014
OBJECTIVE: To examine the timing and duration of RSV bronchiolitis hospital admission among term and preterm infants in England and to identify risk factors for bronchiolitis admission.
A Bottle, A Bush, Alex Bottle, Azeem Majeed, B Muller-Pebody, BJ Law, BN Manktelow, C Wren, CB Hall, CB Hall, CG Garcia, D Wang, DK Shay, GK Spurling, H Nair, H Patel, J Barben, J Murray, Joanna Murray, JS Tregoning, L Bont, LG Stensballe, M Koehoorn, Mike Sharland, ML Houben, Neena Modi, NG Papadopoulos, Oliver Schildgen, P Aylin, Paul Aylin, RL Smyth, S Beck, S Ladhani, S Saxena, SA Deshpande, Sonia Saxena   +35 more
core   +3 more sources

Lactylation Enhances the Activity of Lactate Dehydrogenase A and Promotes the Chemoresistance to Cisplatin Through Facilitating DNA Nonhomologous End Junction in Lung Adenocarcinoma

Advanced Science, EarlyView.
Lactylation, linked to glycolysis, is poorly understood in regulation. It is found that LDHA is lactylated at Lys81/Lys318 by AARS1, boosting its activity and cellular lactylation via positive feedback in LUAD. Lactylation regulates NHEJ‐related proteins; their delactylation impairs NHEJ and increases cisplatin sensitivity, offering anticancer insights.
Jizhuo Li, Wenze Xun, Xijie Wang, Ruiguang Luo, Qifan Hu, Zhaocai Zhou, Jian Yuan, Yanan Wang, Xiaorui Wan, Tao Zhao, Tianyu Han, Jian‐Bin Wang   +11 more
wiley   +1 more source

Single‐Cell Insights Into Macrophage Subtypes in Pulmonary Infections

Advanced Science, EarlyView.
This review highlights the dynamic plasticity of macrophages during pulmonary infections and proposes an integrative framework defining six functional subtypes: Inflam‐Ms, Hub‐Ms, Reg‐Ms, Prolif‐Ms, Memory‐Ms, and Senesc‐Ms. Single‐cell omics delineate their distinct roles in homeostasis and infection, refining our understanding of macrophage ...
Zhaoheng Lin, Yuxiao Zheng, Yu Zhong, Hongyan Wang   +3 more
wiley   +1 more source