Results 141 to 150 of about 5,063 (242)

Beta‐blockers in patients with heart failure with reduced ejection fraction and concomitant chronic obstructive pulmonary disease: Cardiovascular and respiratory outcomes

European Journal of Heart Failure, EarlyView.
In total, 5084 patients from Swedish registries with both heart failure (HF) with reduced ejection fraction (HFrEF) and chronic obstructive pulmonary disease (COPD) were included. Confounding was handled by overlap weighting based on propensity scores for beta‐blocker use. Patients were followed up for 5 years, or until death, emigration from Sweden or
Benedikt N. Beer, Lina Benson, Christian Basile, Benedikt Schrage, Peter Moritz Becher, Stefan Blankenberg, Paulus Kirchhof, Barna Szabó‐Söderberg, Marco Metra, Anne Lindberg, Egidio Imbalzano, Giuseppe M. C. Rosano, Patric Karlström, Peter G.M. Mol, Raffaele Scorza, Lars H. Lund, Felix Lindberg, Gianluigi Savarese   +17 more
wiley   +1 more source

Interpretation of in vitro concentration‐response data for risk assessment and regulatory decision‐making: Report from the 2022 IWGT quantitative analysis expert working group meeting

Environmental and Molecular Mutagenesis, EarlyView.
Abstract Quantitative risk assessments of chemicals are routinely performed using in vivo data from rodents; however, there is growing recognition that non‐animal approaches can be human‐relevant alternatives. There is an urgent need to build confidence in non‐animal alternatives given the international support to reduce the use of animals in toxicity ...
Marc A. Beal, Guangchao Chen, Kerry L. Dearfield, Min Gi, Bhaskar Gollapudi, Robert H. Heflich, Katsuyoshi Horibata, Alexandra S. Long, David P. Lovell, Barbara L. Parsons, Stefan Pfuhler, John Wills, Andreas Zeller, George Johnson, Paul A. White   +14 more
wiley   +1 more source

MUCOID IMPACTION OF THE BRONCHI

Journal of Thoracic Surgery, 1951
openaire   +2 more sources

Cytotoxicity of 19 Pesticides in Rainbow Trout Gill, Liver, and Intestinal Cell Lines

Environmental Toxicology and Chemistry, EarlyView.
Abstract The rainbow trout gill cell line (RTgill‐W1), via test guideline 249 of the Organisation for Economic Co‐operation and Development, has been established as a promising New Approach Methodology, although to advance confidence in the method more case studies are needed that: 1) expand our understanding of applicability domains (chemicals with ...
Sophie Emberley‐Korkmaz, Krittika Mittal, Na'im Temlock, Jessica Head, Niladri Basu   +4 more
wiley   +1 more source

Kaempferol Alleviates Acrolein‐Induced Lung Injury In Vitro and In Vivo by Binding to Peli2 and Disrupting the Peli2‐NLRP3 Interaction

Food Frontiers, EarlyView.
Abstract Acrolein (ACR) is a highly toxic agent that induces lung inflammation and causes acute lung injury (ALI). However, effective treatments for ACR‐induced ALI are currently lacking. We investigated the protective effects of kaempferol (Kae) against ACR‐induced ALI using in vitro (HBE and BEAS‐2B cells) and in vivo murine models (male C57BL/6 mice)
Juanjuan Ma, Zhao Yin, Jie Zheng, Xingyou Mo, Shaoji Li, Hua Liu, Shiyi Ou   +6 more
wiley   +1 more source

Nerve growth factor levels and localisation in human asthmatic bronchi [PDF]

, 2002
C. Olgart Höglund, F. de Blay, JP Oster, Catherine Duvernelle, Olivier Kassel, G. Pauli, Nelly Frossard   +6 more
openalex   +1 more source

Natural Products Targeting Notch Signaling in Cancer: Mechanistic Insights and Food‐Based Chemoprevention Potential

Food Frontiers, EarlyView.
The Notch signaling pathway plays a dual role in cancer, acting as both a tumor promoter and suppressor depending on cellular context. This review highlights how natural products modulate Notch signaling to inhibit tumor initiation, progression, angiogenesis, and cancer stem cell maintenance.
Rabab Fatima, Parteek Prasher, Mousmee Sharma, Dietrich Büsselberg, Gabriela Figueroa‐González, Octavio Daniel Reyes‐Hernández, Edgar Yebrán Villegas‐Vázquez, Hernán Cortés, Gerardo Leyva‐Gómez, Jesús Herrera‐Bravo, Solomon Habtemariam, Javad Sharifi‐Rad, Monica Butnariu, Cristian Berar, Angela Caunii, William C. Cho   +15 more
wiley   +1 more source

Relaxation of proximal and distal isolated human bronchi by halothane, isoflurane and desflurane [PDF]

, 2002
F.J. Mercier, Emmanuel Naline, Maine Luellah Demaret Bardou, O. Georges, A. Denjean, D. Benhamou, Charles Advenier   +6 more
openalex   +1 more source

An unusual case of congenital short trachea with very long bronchi mimicking bronchial asthma [PDF]

, 2002
F Ravenna
openalex   +1 more source

Over one‐third of cancer cases and two‐fifths of cancer deaths in southern China are preventable: Insights from the latest representative population‐based cancer registry data and risk factor survey

International Journal of Cancer, EarlyView.
What's New? This study quantified the cancer burden attributable to modifiable risk factors in Guangdong, the most populous and economically advanced province in southern China. By evaluating 15 modifiable risk factors, the study reveals that over one‐third of cancer cases and two‐fifths of cancer deaths in the region could potentially be prevented ...
Xiaolan Wen, Yu Liao, Jiayue Li, Qian Zhu, Xinmei Lin, Bingfeng Han, Li Li, Ru Chen, Ruilin Meng, Ni Xiao, Xueyan Zheng, Xiaojun Xu, Dejian Zhao, Yue Gao, Liming Pu, Ye Wang, Wenqiang Wei, Shaoming Wang   +17 more
wiley   +1 more source