Results 131 to 140 of about 359,662 (297)

Impulse Oscillometry Detected Physiological Abnormalities More Frequently Than Spirometry in Children With Largely Preserved Lung Function

open access: yesActa Paediatrica, EarlyView.
ABSTRACT Aim We compared how well impulse oscillometry (IOS) and spirometry detected small airway dysfunction (SAD) in children with asthma and evaluated associations between IOS abnormalities, asthma control, and asthma severity. Methods This observational study comprised 106 children aged 6–18 years with asthma who underwent IOS and spirometry before
Paola Di Filippo   +7 more
wiley   +1 more source

The discovery and development of ensifentrine: A novel inhaled dual PDE3/4 inhibitor having ‘bifunctional’ bronchodilator and anti‐inflammatory activity

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Ensifentrine (formerly called RPL 554) is a novel, first in class, inhaled bifunctional dual PDE3/4 inhibitor for the treatment of chronic respiratory diseases. Ensifentrine exhibits both bronchodilation via PDE3 inhibition and anti‐inflammatory activity via PDE4 inhibition.
Clive Page
wiley   +1 more source

Effects of lifelong sulforaphane intake on behavioural, neurochemical and biomolecular dysfunctions in the BTBR T+ Itpr3tf/J mouse model of autism spectrum disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Created in BioRender. Schiavone, S. (2026). https://BioRender.com/cy0xq6z. Abstract Background and Purpose Autism spectrum disorders (ASD) are multifactorial neurodevelopmental conditions associated with oxidative stress and neuroinflammation across critical developmental periods.
Vladyslav Sikora   +8 more
wiley   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

open access: yesClinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole   +4 more
wiley   +1 more source

PATHOPHYSIOLOGY OF BRONCHIAL ASTHMA.

open access: yes
Bronchial asthma is a non-infectious chronic disease of the respiratory tract. Knowing its pathophysiology helps a lot. It helps to avoid sudden attacks.
Oltinov, Sardor
core   +1 more source

Use of thoracic computed tomography in the diagnosis of a pulmonary myxoma in a horse

open access: yesEquine Veterinary Education, EarlyView.
Summary This case describes the first reported antemortem computed tomographic (CT) examination of the thorax in an adult horse. A 13‐year‐old Australian Stock Horse gelding presented for a severe cough, epistaxis and haemoptysis after a 1‐year history of suspected equine asthma.
E. Hodgson   +5 more
wiley   +1 more source

Associations Between Asthma and Device‐Based Measured Physical Activity Among Children and Adolescents: The Lolland–Falster Health Study

open access: yesJournal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this study was to examine whether asthma in children and adolescents is associated with a difference in physical activity (PA) both regarding intensity (sedentary, light, moderate‐vigorous) and behaviour (lying, sitting, standing, walking, running and biking).
Christian Rønn   +8 more
wiley   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru   +2 more
wiley   +1 more source

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