Results 141 to 150 of about 572,905 (336)
Allergy, EarlyView.Studies suggest that type 2 inflammatory diseases are driven by overactivation of the IL4/IL13 pathway, manifesting differently in distinct tissues. We performed quantitative analyses using several large independent datasets to explore the interrelation of type 2 inflammatory diseases based on co‐prevalence, genetic predispositions, and transcriptomic ...
Jennifer D. Hamilton +19 more
wiley +1 more source
A Prevalence Study of Children Suffering from Bronchial Asthma with Special Emphasis on the Possible Relationship with "Chironomid Asthma" in Lake Suwa Area [PDF]
, 1991 The present study aims to examine the possiblerelationship between the prevalence of bronchial asthma among children and the area damage made by adult chironomid in Lake Suwa Area where has been notorious with environmental hazard through massive ...
平林, 公男 +4 more
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MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation
Allergy, EarlyView.In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata +6 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT Advances in asthma therapies have shown that clinical remission may be an achievable therapeutic goal for patients with asthma. This review discusses the current definitions of remission in asthma, the predictors of remission, airway inflammation/epithelial damage in asthma remission, airway remodeling, paradigms in defining remission and ...
Fatma Esra Gunaydin +4 more
wiley +1 more source
Effect of Dupilumab on Airway Inflammation in Patients With Persistent Asthma
Allergy, EarlyView.EXPEDITION (NCT02573233) assessed the effects of dupilumab on airway inflammation in patients with persistent asthma using bronchoscopy and gene expression analysis. Dupilumab showed no appreciable effect on inflammatory cell types in biopsies or BALF samples.
Michael E. Wechsler +22 more
wiley +1 more source
SOME FUNCTIONAL FEATURES OF COURSE OF BRONCHIAL ASTHMA COMBINED WITH ESSENTIAL HYPERTENSION
Acta Biomedica Scientifica, 2015 One of the frequent conditions which accompany bronchial asthma is essential hypertension. The authors compared the functional characteristics of patients with isolated asthma and bronchial asthma combined with essential hypertension.
O. M. Uryasev, A. I. Rogachikov
doaj
Allergy, EarlyView.We aimed to characterise Alternaria sensitisation trajectories from childhood to adulthood; we compared SPT, whole‐extract sIgE and rAlt a 1, and assessed their longitudinal association with asthma and rhinitis in the Isle of Wight birth cohort. Alternaria sensitisation in the Isle of Wight Birth Cohort emerges mainly in late adolescence and, when ...
Mohammad Leily +7 more
wiley +1 more source
Relationship between influx of yellow dust and bronchial asthma mortality using satellite data [PDF]
, 2010 The amount of yellow dust that reaches Japan has recently increased. This increase could worsen asthma attacks. However, it is difficult to conduct quantitative research because yellow dust is widely dispersed. Therefore, very few epidemiological studies
Nmor, Jephtha Christopher +7 more
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The metalloproteinase ADAM17 promotes acute lung inflammatory responses during pancreatitis
British Journal of Pharmacology, EarlyView.Background and Purpose Acute pancreatitis (AP) is a multifactorial upper gastrointestinal inflammatory disorder that in severe cases (~20% of all AP) is associated with substantial morbidity and mortality, the latter coincident with multiorgan dysfunction, particularly acute lung injury (ALI).
Shermin Chan +17 more
wiley +1 more source
Does consanguinity increase the risk of bronchial asthma in children?
Annals of Thoracic Medicine, 2008 There is a high prevalence of consanguinity and bronchial asthma in Saudi Arabia. The objective of this study is to explore the effect of parental consanguinity on the occurrence of bronchial asthma in children.
El Mouzan Mohammad +4 more
doaj