Results 141 to 150 of about 252,536 (246)

The global Asthma report 2014 [PDF]

, 2014
Provides up-to-date information about asthma, and summarises what is known and where the gaps lie. The report also makes recommendations to authorities on required actions.

core  

Emerging Paediatric Uses of Dupilumab Beyond Approvals

Clinical &Experimental Allergy, EarlyView.
Dupilumab, through IL‐4Rα blockade, shows promising efficacy beyond approved indications in paediatric diseases driven by T2 inflammation. Emerging evidence—mainly from small studies—supports improvements in disease severity and quality of life, highlighting its potential as a targeted, steroid‐sparing therapy while underscoring the need for ...
Simone Foti Randazzese, Anna Calamita, Diletta D'Angelo, Alessia Marseglia, Esther Mesa Lombardero, Sara Pedersoli, Micol Tedeschi, Mara De Amici, Sara Manti, Valeria Brazzelli, Amelia Licari, Gian Luigi Marseglia   +11 more
wiley   +1 more source

Long Non‐Coding RNA, Like NEAT1 and MALAT1, in Asthma: Mechanisms and Therapeutic Potential

Clinical &Experimental Allergy, EarlyView.
Long non‐coding RNA, like NEAT1 and MALAT1, is emerging as a regulator of asthma‐related inflammation, airway remodelling, viral responses and cell death pathways, and are promising targets for future therapeutics. ABSTRACT Asthma affects millions worldwide. Long non‐coding RNA (lncRNA) are emerging as important factors in the pathophysiology of asthma
Ashlyn Poole, Ingrid Laing, Ryan Mead‐Hunter, Peter Le Souef, Guicheng Zhang   +4 more
wiley   +1 more source

Learning requirements on the bronchial asthma of the integral general medicine specialists

, 2014
Introduction: the poor control of asthma symptoms is a serious problem thatmight bring about adverse economic and clinical consequences. The detection oflearning requirements in this field is a starting point for the search of a pedagogicsolution that ...
Iriarte Leonardo Castillo, Pazitkova Tatiana de la Vega   +1 more
core  

Revisiting Platelet‐Activating Factor in Asthma: An Exploratory Metabolomics Analysis of PAF C‐18:1 and Type 2 Inflammation

Allergy, EarlyView.
Noeul Kang, Young Jin Pyung, Deog Kyeom Kim, Cheol‐Heui Yun, Hyun Woo Lee   +4 more
wiley   +1 more source

A Motor Vehicle Crash as an Early Signal of Alzheimer's Disease and Related Dementias

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background People with Alzheimer's disease and related dementias (ADRD) are at increased risk of motor vehicle crash (MVC) due to cognitive decline, which often begins years before diagnosis. MVC could serve as an indicator of ADRD‐related cognitive impairment and facilitate earlier diagnosis.
Nina R. Joyce, Steven Balog, Rachel Gaither, Melissa R. Pfeiffer, Fiona Bhondoekhan, Brian R. Ott, Seth A. Margolis, Alison E. Curry, Andrew R. Zullo   +8 more
wiley   +1 more source

A Pilot Placebo‐Controlled Randomized Trial of Repeated High‐Dose Intravenous Magnesium Sulphate and High‐Dose Nebulized Budesonide for Severe Asthma in the Paediatric Emergency Department

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Objective Determine if high‐dose intravenous magnesium with/without nebulized budesonide for children with acute severe asthma is safe and reduces time to medical readiness for discharge compared to standard intravenous magnesium. Methods Either 2 doses of intravenous magnesium or 1 dose and placebo, each with/without high‐dose nebulized ...
Khalid Alansari, Fatin Abou Moussa, Hadi Abu Rasheed, Bruce L. Davidson, Khalid Yousif Ibrahim, Mahmoud Alrifaai   +5 more
wiley   +1 more source

Associations Between Asthma and Device‐Based Measured Physical Activity Among Children and Adolescents: The Lolland–Falster Health Study

Journal of Paediatrics and Child Health, EarlyView.
ABSTRACT Aim The aim of this study was to examine whether asthma in children and adolescents is associated with a difference in physical activity (PA) both regarding intensity (sedentary, light, moderate‐vigorous) and behaviour (lying, sitting, standing, walking, running and biking).
Christian Rønn, Søren Malte Rasmussen, Peter Kamstrup, Therese Lockenwitz Petersen, Jan C. Brønd, Jakob Stokholm, Vibeke Backer, Howraman Meteran, Randi Jepsen   +8 more
wiley   +1 more source

Research progress on free fatty acid receptors and bronchial asthma

Bronchial asthma is a chronic respiratory disease characterized by reversible airflow limitation, including airway hyperresponsiveness, airway inflammation and airway remodeling.
Na Lin, Juntao Lin, Fangxin Cao, Gai Yang, Xintong Wang   +4 more
core   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source