Results 171 to 180 of about 359,662 (297)

GENETIC FOUNDATIONS OF THE BRONCHIAL ASTHMA

, 2008
The article overviews the results of the studies of the genetic foundations of predisposition to the bronchial asthma. The authors provide detailed information on the molecular and genetic mechanisms of the bronchial asthma, roles performed by the ...
N.I. Voznesenskaya, V.G. Pinelis, L.S. Namazova, A.Yu. Asanov, N.V. Zhurkova   +4 more
core  

Peptide‐Linked Bivalent Nanobody Constructs as Positive Allosteric Modulators of the Calcium‐Sensing Receptor

Basic &Clinical Pharmacology &Toxicology, Volume 139, Issue 6, December 2026.
ABSTRACT We previously developed nanobodies acting as positive allosteric modulators (PAMs) of the calcium‐sensing receptor (CaSR). Here, we sought to develop more potent CaSR modulators by creating bivalent nanobody constructs using ‘tail‐to‐head’ peptide‐linker conjugation.
Mahdis Nabipour, Charlotte Hagen Skadhauge, Line Juel Rasmussen, Hans Bräuner‐Osborne, Jesper M. Mathiesen, Anders A. Jensen   +5 more
wiley   +1 more source

Effects of metabolic syndrome on pulmonary infection in pediatric bronchial asthma: a narrative review. [PDF]

Front Pediatr
He L, Ye Y.
europepmc   +1 more source

From Static Choices to Navigating Clinical Trajectories: Reframing Therapeutic Reasoning in Medical Education

Journal of Evaluation in Clinical Practice, Volume 32, Issue 8, December 2026.
ABSTRACT Problem Therapeutic reasoning is central to clinical practice and informed by established frameworks such as evidence‐based medicine and shared decision‐making. In educational settings, however, therapeutic decision‐making is frequently taught and assessed as a discrete choice among predefined treatment options.
Yskert von Kodolitsch, Tilman Dreyer, Thomas Wick, Sigrid Harendza   +3 more
wiley   +1 more source

Comparative Clinical Presentation of Bronchial Asthma in Adults and Children in North India. [PDF]

Cureus
Tripathi S, Kant S, Verma A, Bajpai J, Gupta S, Tripathi P, Singh A.   +6 more
europepmc   +1 more source

Canoe full of hot paddlers: TRPV1 neurons steering cardiorespiratory control

The Journal of Physiology, EarlyView.
Richard J. A. Wilson, Nicholas Jendzjowsky   +1 more
wiley   +1 more source

Regulation of IL‐13 Signaling by Retinoic Acid in Airway Epithelial Cells

The FASEB Journal, Volume 40, Issue 21, 15 November 2026.
Our proteomics and subsequent biochemical analyses reveal the effects of retinoic acid receptor (RAR) agonists, ATRA (pan‐RAR agonist), or CD1530 (RARγ agonist) in counteracting molecular changes induced by IL‐13 relevant to airway inflammation and remodeling, such as proteins involved in epithelial‐to‐mesenchymal transition (EMT) and extracellular ...
Vanshika Patel, Jianshi Yu, Mehari Weldemariam, Paul Shapiro, Deepak A. Deshpande, Maureen A. Kane   +5 more
wiley   +1 more source

Apigenin Derivatives Alleviate OVA-Induced Oxidative Stress in Bronchial Asthma: A Structure-Activity Relationship Study. [PDF]

Molecules
Li C, Xiao L, Wu W, Kong L, Yue S, Zhan Z, Xu J, Ma W.   +7 more
europepmc   +1 more source

Pharmacokinetics and safety of tezepelumab in children with mild, moderate or severe asthma and adolescents with mild‐to‐moderate asthma

British Journal of Clinical Pharmacology, Volume 92, Issue 11, Page 3819-3830, November 2026.
Abstract Aim Tezepelumab is a human monoclonal antibody that blocks the activity of thymic stromal lymphopoietin and is approved for adolescents and adults with severe asthma. This analysis assessed pharmacokinetics (PK), pharmacodynamics and safety of tezepelumab up to 85 days postdose in adolescents and children.
Anna Lundahl, Jonathan Grigg, Lubna Abuqayyas, Piotr Kuna, Gillian Hunter, Beata Pawlikowska, Jacob Leander, Michael Levin, Atul Gupta, James Paton, Katharine C. Pike, Jane R. Parnes, Gun Almqvist, Stephanie L. Roseti, on behalf of the study investigators   +14 more
wiley   +1 more source

Efficacy of Yupingfeng powder in the treatment of bronchial asthma in adults: a systematic review and meta-analysis. [PDF]

Front Pharmacol
Zhang Q, Zhang N, Zheng Y, Zhou J, Liu L, Gang D.   +5 more
europepmc   +1 more source