Results 41 to 50 of about 9,663 (188)

Diagnostic work-up in patients with possible asthma referred to a university hospital [PDF]

, 2015
OBJECTIVE: The best strategy for diagnosing asthma remains unclear. Accordingly, the aim of this study was to evaluate diagnostic strategies in individuals with possible asthma referred to a respiratory outpatient clinic at a university hospital. METHODS:
Backer, Vibeke, Bødtger, Uffe, Porsbjerg, Celeste, Seersholm, Niels, Sverrild, Asger, Ulrik, Charlotte Suppli   +5 more
core   +2 more sources

Assessment of Allergen-Induced Respiratory Hyperresponsiveness before the Prescription of a Specific Immunotherapy

Allergy & Rhinology, 2015
Background Asymptomatic sensitization is a frequent condition that must be considered before the indication of allergic-specific immunotherapy. Objective The aim of this study was to appreciate and correlate the local and spirometric changes elicited by ...
Celso Eduardo Olivier M.D., Ph.D., Daiana Guedes Pinto Argentão B.Biomed, Regiane Patussi dos Santos Lima B.Biomed, Mariana Dias da Silva Pharm.D., Raquel Acácia Pereira Gonçalves dos Santos B.S.N., Natalia Fabbri D.Physio, Ph.D.   +5 more
doaj   +1 more source

Estudo da hiper-responsividade brônquica em pacientes portadores de refluxo gastroesofágico Bronchial hyperreactivity in patients with gastroesophageal reflux disease

Jornal Brasileiro de Pneumologia, 2005
OBJETIVO: O intuito deste trabalho foi evidenciar a existência desse reflexo vagal, através de uma broncoprovocação, em pacientes portadores de refluxo gastroesofágico.
Mônica Silveira Lapa, Roberto Rodrigues Júnior, Elie Fiss   +2 more
doaj   +1 more source

PRMT5 Mediates Sepsis‐Associated Lung Injury by Modulating JAK1 Arginine Methylation: A Mechanism Study

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Lung injury is a common complication in critical sepsis. PRMT5 is implicated in endothelial inflammation and lung diseases, but its role in sepsis‐associated lung injury remains unclear. This study collected clinical sepsis samples and detected the mRNA expression of PRMT5.
Bo Wang, Zhen Ge, Fei‐Xiang Chen
wiley   +1 more source

Increased IL-6 and IL-4 in exhaled breath condensate of patients with nasal polyposis. [PDF]

, 2009
BACKGROUND AND AIM: Nasal polyposis (NP) occurs in about 1-4% of the worldwide population. Increased plasma concentrations of different pro-inflammatory cytokines have been observed in NP, and might be related to the pathogenesis of this syndrome.
Barbaro, M. P., Carpagnano, Ge, Carrat\ufa, P, Condreva, T, Di Gioia, G, Gelardi, M, Resta, O, Spanevello, Antonio   +7 more
core   +1 more source

Hyperreactivity of the bronchi in children, whooping cough convalescents

Журнал инфектологии, 2020
Objective: to assess the presence and degree of bronchial hyperreactivity in convalescents of whooping cough based on the results of bronchial provocation tests.Materials and methods.
Yu. V. Nesterova, A. V. Orlov, I. V. Babachenko   +2 more
doaj   +1 more source

LncRNA NORAD Enhances Inflammatory Injury in Sepsis‐Associated Acute Lung Damage Through miR‐150‐5p/STAT1‐Dependent NF‐κB Activation

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Acute lung injury (ALI) is a severe complication of sepsis, yet the role of lncRNA NORAD in its pathogenesis remains unclear. Using LPS‐stimulated BEAS‐2B and HBEC3‐KT cells as well as cecal ligation and puncture (CLP)‐induced ALI models in C57BL/6 mice, we found that NORAD expression was markedly upregulated and promoted cell injury ...
Han Liu, Xi‐Xi Chen, Gui‐Hua Wei, Feng Li, Hai‐Yan Zong   +4 more
wiley   +1 more source

気管支喘息における気管支肺胞洗浄液中の細胞成分に対する加齢および副腎皮質ホルモンの影響 [PDF]

, 2002
Effects of aging and glucocorticoid therapy on bronchoalveolar lavage (BAL) cells, particularly lymphocytes, neutrophils and eosinophils, were examined in 81 patients with asthma. 1.
Ashida, Kozo, Hosaki, Yasuhiro, Mitsunobu, Fumihiro, Nishida, Norikazu, Okamoto, Makoto, Takata, Shingo, Tanizaki, Yoshiro, Tsugeno, Hirofumi, Yokoi, Tadashi   +8 more
core   +1 more source

The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review

Swiss Medical Weekly, 2019
OBJECTIVE Asthma is associated with bronchial hyperresponsiveness, assessed by bronchial provocation tests such as the mannitol test. We aimed to assess the data on sensitivity and specificity of the mannitol test in diagnosing asthma.
Philipp Kernen, Esther H. Steveling-Klein, Ramon T. Saccilotto, Heike Raatz, Matthias Briel, Michael T. Koller, Marie Westwood, Heiner C. Bucher, David Miedinger, Jörg D. Leuppi   +9 more
doaj   +1 more source

Endoplasmic reticulum stress and the unfolded protein response in lung diseases: molecular pathways and therapeutic interventions

The Journal of Pathology, EarlyView.
Abstract Endoplasmic reticulum stress (ERS) occurs when the protein‐folding capacity of the endoplasmic reticulum (ER) is overwhelmed, triggering the unfolded protein response (UPR) to restore homeostasis. However, severe or persistent ERS can shift the UPR toward pro‐inflammatory, apoptotic, and fibrotic signaling, thereby exacerbating tissue injury ...
Lanlan Song, Yichen Liu, Chen Xu, Yaochen Zhang, Kaiming Xu, Dan Yao, Xiaoying Huang   +6 more
wiley   +1 more source