Birch pollen and PM10 are key determinants of clinical symptoms, particularly in asthma. Allergic people react stronger to the pollen collected in the highly polluted area than in the less polluted areas. When evaluating the effectiveness of allergen immunotherapy, it is essential to consider not only pollen concentrations but also levels of air ...
Maria Czarnobilska +5 more
wiley +1 more source
Corticosteroid-Sparing Effect of Chromoglycate Sodium and Nedocromil
The most appropiate management for bronchial asthma is the control of airway inflammation. Corticosteroids are the most effective anti-inflammatory drugs available, but they have a number of side effects; most of these are dose-dependent.
A. F. Capristo +3 more
doaj +1 more source
Investigation and Analysis of the Current Status of Bronchial Provocation Testing in Guangdong Province [PDF]
Background The prevalence of bronchial asthma has been rising annually, yet primary healthcare institutions still face difficulties in early diagnosis and treatment. Bronchial provocation test (BPT) is an important diagnostic tool with significant value.
WU Zhongping, ZHENG Jingping, GAO Yi, CHEN Xiaoliang
doaj +1 more source
Case of seropositive allergic bronchopulmonary aspergillosis in a 10-year-old girl without previously documented asthma [PDF]
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease due to bronchial colonization of Aspergillus fumigatus that occurs in susceptible patients with asthma or cystic fibrosis. A 10-year-old girl was referred to the Department
Jeong Eun Shin +5 more
doaj +1 more source
Nomenclature on Immune‐Mediated Drug Reactions: An EAACI Position Paper
ABSTRACT Over the past several decades, there have been significant advances in our understanding of both immunological and pharmacological mechanisms of adverse drug reactions (ADRs). Immune‐mediated drug reactions (IMDRs) represent a small proportion of ADRs and are caused by a pathological activation of the immune system or inflammatory pathways ...
Maria J. Torres +19 more
wiley +1 more source
Influence of sensitization and allergen provocation procedures on the development of allergen-induced bronchial hyperreactivity in conscious, unrestrained guinea-pigs [PDF]
The effects of different sensitization and allergen provocation regimens on the development of allergen-induced bronchial hyperreactivity (BHR) to histamine were investigated in conscious, unrestrained guinea-pigs.
C. G. Olymulder +9 more
core +1 more source
Protective effect of bronchial challenge with hypertonic saline on nocturnal asthma
Inhalation of hypertonic saline (HS) causes bronchoconstriction in asthmatic subjects. Repeated inhalation of HS leads to substantially reduced bronchoconstriction, known as the refractory period.
M.C. Borges +3 more
doaj
Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases
ABSTRACT Type 2 (T2) immunity is classically associated with defense against helminths and environmental threats, from a physiological perspective, and with allergies and eosinophilic inflammatory diseases, in a pathological sense. However, growing evidence reveals that T2 pathways also support other essential homeostatic functions, including tissue ...
Rodrigo Jiménez‐Saiz +22 more
wiley +1 more source
Does asthma control as assessed by the asthma control test reflect airway inflammation?
Background and aims The treatment of asthmatic patients is particularly focused on the control of symptoms as well as functional and inflammatory parameters.
Bora Mine +6 more
doaj +1 more source
The Origins of Allergy: An Outside‐In, Bioenergetic Hypothesis
ABSTRACT Allergic disease has risen too rapidly for inherited susceptibility to explain it, and the risk variants so far reported lie in the epithelial barrier and in type‐2 immunity. We propose a five‐layer model in which epithelial barrier and bioenergetic dysfunction may precede and promote type‐2 immune deviation rather than arise solely as its ...
Peter K. Smith +9 more
wiley +1 more source

