IntroductionThe aim of this study is to identify the effects of sublingual immunotherapy (SLIT) on immunologic parameters and bronchial-hyper-responsiveness in children with allergic rhinitis to house-dust mite (HDM), through long-term follow-up cohort ...
Jae Hyun Lim +7 more
doaj +1 more source
Case of seropositive allergic bronchopulmonary aspergillosis in a 10-year-old girl without previously documented asthma [PDF]
Allergic bronchopulmonary aspergillosis (ABPA) is a hypersensitivity lung disease due to bronchial colonization of Aspergillus fumigatus that occurs in susceptible patients with asthma or cystic fibrosis. A 10-year-old girl was referred to the Department
Jeong Eun Shin +5 more
doaj +1 more source
Iron Physiology and Its Impact on Atopic Diseases: An EAACI Taskforce Report
ABSTRACT Iron is essential for oxygen transport, energy metabolism, and immune regulation. Yet iron deficiency is the most common micronutrient disorder across all age groups, affecting nearly one quarter of the global population. Iron deficiency triggers nutritional immunity, a host defense mechanism that withholds and redistributes iron, contributing
Franziska Roth‐Walter +19 more
wiley +1 more source
Aspirin-Exacerbated Asthma [PDF]
This review focuses on aspirin-exacerbated asthma (AEA). The review includes historical perspective of aspirin, prevalence, pathogenesis, clinical features and treatment of AEA.
Mathew Varghese, Richard F Lockey
core +1 more source
MAIT Cells Suppress IgE‐Mediated Asthma via IFNγ‐Dependent B Cell Regulation
In this study, we demonstrate that MAIT cell antagonism during sensitization and challenge with HDM worsens the development of airway hyperreactivity without effects on type 2 or 17 associated cytokine production or lung inflammation. Rather, MAIT cells appear to regulate HDM‐induced asthma through direct inhibition of IgE production.
Angela M. Cannata +6 more
wiley +1 more source
A standard, single dose of inhaled terbutaline attenuates hyperpnoea-induced bronchoconstriction and mast cell activation in athletes [PDF]
Release of broncho-active mediators from mast cells during exercise hyperpnoea is a key factor in the pathophysiology of exercise-induced bronchoconstriction (EIB).
A. J. Simpson +16 more
core +2 more sources
Corticosteroid-Sparing Effect of Chromoglycate Sodium and Nedocromil
The most appropiate management for bronchial asthma is the control of airway inflammation. Corticosteroids are the most effective anti-inflammatory drugs available, but they have a number of side effects; most of these are dose-dependent.
A. F. Capristo +3 more
doaj +1 more source
Investigation and Analysis of the Current Status of Bronchial Provocation Testing in Guangdong Province [PDF]
Background The prevalence of bronchial asthma has been rising annually, yet primary healthcare institutions still face difficulties in early diagnosis and treatment. Bronchial provocation test (BPT) is an important diagnostic tool with significant value.
WU Zhongping, ZHENG Jingping, GAO Yi, CHEN Xiaoliang
doaj +1 more source
Therapeutic potential of natural products in cancer immunotherapy: Advances and challenges
This review systematically outlines the mechanisms underlying tumour immunotherapy resistance and elucidates the role of natural products in enhancing therapeutic efficacy as immunomodulatory adjuvants. Abstract Immunotherapy has emerged as a clinically pivotal approach in cancer treatment, but its application remains limited to a small subset of ...
Rao Hu +6 more
wiley +1 more source
Impact of allergic rhinitis on asthma: effects on bronchodilation testing [PDF]
A remarkable relationship exists between the upper and lower airways. Bronchial obstruction is a paramount feature of asthma, and its reversibility is considered a main step in asthma ...
Ciprandi, G +4 more
core +1 more source

