Results 181 to 190 of about 83,414 (306)

Tetrahedral DNA Nanostructure‐Based Biomimetic Nanovesicles Attenuate Sepsis‐Associated ARDS by Suppressing Glycolysis via the BMAL1/PFKFB3 Axis

Advanced Science, Volume 13, Issue 34, 19 June 2026.
Upon inhalation, RM@TNT could persist long‐term in the diseased lungs, while undergoing disintegration to release TNT specifically within the ROS‐rich pathological microenvironments of SA‐ARDS. The released TNT was then precisely delivered to AMs via Tuftsin, where it released Nob intracellularly to activate BMAL1 expression, thus inhibiting AM ...
Yunlong Zhang, Bin Li, Zhijin Fan, Yan Yan, Fei Ma, Changting He, Shiping Liu, Mingliang Pan, Zhou Pan, Huijuan Wang, Xinting Fu, Jiamei Wang, Yue Jia, Qin Gu, Duo Jiang, Xueting Liu, Bohua Ren, Qinqin Wang, Yuehua Hei, Han Duan, Yanqiu Wu, Zihui Wei, Liying Zhan, Yuhui Liao   +23 more
wiley   +1 more source

Identification of Exhaled Volatile Organic Compounds Biomarkers for Lung Cancer Under Data‐Limited Conditions Using Data Augmentation and Multi‐View Feature Selection

Advanced Intelligent Discovery, Volume 2, Issue 3, June 2026.
This work introduces a novel framework for identifying non‐small cell lung cancer biomarkers from hundreds of volatile organic compounds in breath, analyzed via gas chromatography‐mass spectrometry. This method integrates generative data augmentation and multi‐view feature selection, providing a stable and accurate solution for biomarker discovery in ...
Guancheng Ren, Bohao Liu, Zhiyuan Qu, Xue Jiang, Heng Zhao, Danyao Qu, Ruizhi Ning, Chen Su, Taoping Liu, Guangjian Zhang, Weiwei Wu   +10 more
wiley   +1 more source

The Application Value of Bronchoalveolar Lavage Fluid Metagenomic Next-Generation Sequencing in Moderate-to-Severe Bronchiectasis. [PDF]

J Clin Lab Anal
Li J, Quan Q, Chen J, Jian X, Zhan W, Wang J, Jiang R.   +6 more
europepmc   +1 more source

Correction: Metagenomic and metatranscriptomic profiling of bronchoalveolar lavage fluid identifies microbial and host biomarkers of drug-resistant tuberculosis. [PDF]

Front Cell Infect Microbiol
Zhang H, Zhang L, Yang B, Gao C, Liu H, Zhang Y, Chen X.   +6 more
europepmc   +1 more source

Molecular analysis of bronchoalveolar lavage fluid to assist pulmonary lymphoma diagnoses. [PDF]

ERJ Open Res
Kido T, Sakamoto N, Hara A, Kato T, Yoshimura M, Yamauchi S, Iketani C, Ozasa M, Yura H, Takemoto S, Takazono T, Ishimoto H, Tsuruda K, Imaizumi Y, Obase Y, Ishimatsu Y, Nishino T, Miyazaki Y, Yanagihara K, Mukae H.   +19 more
europepmc   +1 more source

Intravenous lanadelumab for the treatment of moderately ill COVID‐19 patients

British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1685-1695, June 2026.
Aims Kallikrein‐kinin system (KKS) dysregulation is hypothesized to play a pathogenetic role in COVID‐19‐associated pulmonary oedema. To investigate the efficacy and safety of intravenous lanadelumab, a monoclonal antibody that inhibits plasma kallikrein, in COVID‐19, we conducted a phase 2, open‐label, randomized‐controlled, proof‐of‐concept ...
Job J. Engel, Christine van Linge, W. Joost Wiersinga, Ilse J. E. Kouijzer, Quirijn de Mast, Robert‐Jan Hassing, Danique J. H. Huijbens, Helen L. Leavis, Roger Schutgens, Coen Maas, Kit C. B. Roes, Frank L. van de Veerdonk, Roger Brüggemann   +12 more
wiley   +1 more source

Bronchoalveolar lavage fluid metagenomic datasets: a multidimensional clinical biomolecular resource. [PDF]

Sci Data
Tang H, Liu H, Yuan L, Xie M, Zheng J, Wang J, Zhou J, Yang B, Lou B, Han D.   +9 more
europepmc   +1 more source

Immune Checkpoint Inhibitor Pneumonitis Complicated by Invasive Pulmonary Aspergillosis in COPD: Diagnostic and Therapeutic Challenges

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Checkpoint inhibitor‐associated pneumonitis complicated by invasive pulmonary aspergillosis represents a diagnostic challenge in ICI‐treated patients, particularly those with COPD receiving corticosteroid therapy. Persistent or worsening respiratory abnormalities despite immunosuppressive treatment should prompt reassessment for superimposed ...
Chukwuka Elendu, Ayi T. Debua, Emeka H. Okolo, Halimat O. Sadiq   +3 more
wiley   +1 more source

Spinal Cord Involvement in Neurosarcoidosis: A Case of Longitudinally Extensive Transverse Myelitis at Disease Onset

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Acute‐onset neurological deficits in otherwise healthy individuals warrant a broad differential diagnosis. Neurosarcoidosis presenting as longitudinally extensive transverse myelitis is rare, mimicking demyelinating, infectious, or neoplastic disorders. Early recognition, histopathological confirmation, and timely immunosuppressive therapy are
Areeb Tiwana, Vicky Elias Nahra, Muhammad Adeel Hassan   +2 more
wiley   +1 more source

Multidimensional biomarker profiling of bronchoalveolar lavage fluid for diagnostic and prognostic evaluation of lung cancer: a retrospective observational study. [PDF]

Front Med (Lausanne)
Wang Y, Huang J, Xie X, Li S, Fu Q.
europepmc   +1 more source