Mucosal‐Associated Invariant T Cells in Health and Disease
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao +5 more
wiley +1 more source
Extracellular Vesicles from Bronchoalveolar Lavage Fluid Indicate Early Biomarker Potential and Differentiate Local Lung Injury in a Porcine Model of Asymmetric Acute Lung Injury. [PDF]
Seybold B +10 more
europepmc +1 more source
Alveolar macrophages: development, respiratory homeostasis, signal pathways, diseases, and therapeutic opportunities: During embryonic development, fetal progenitors migrate to the developing lungs via a CX3CR1‐dependent mechanism to establish the TrAM pool.
Sihan Yang +4 more
wiley +1 more source
Molecular analysis of bronchoalveolar lavage fluid to assist pulmonary lymphoma diagnoses. [PDF]
Kido T +19 more
europepmc +1 more source
Intratumoral Microbiota in Fueling Cancer and Steering Treatment Response
Emerging research underscores the tumor‐specific colonization of microbiota and the role of intratumoral microbiota in cancer development and treatment resistance across multiple malignancies. Here, we provide a systematic review exploring the latest biotechnological advancements for studying low‐abundance intratumoral microbiota, their origins ...
Minhui Xu +7 more
wiley +1 more source
Comparative evaluation of probe-capture and conventional metagenomic sequencing across multiple clinical sample types, with analysis of paired bronchoalveolar lavage fluid and blood samples. [PDF]
Liu X +12 more
europepmc +1 more source
Blocking Extracellular Cyclophilin A‐Mediated Adhesion Protects Against Bacterial Infection
eCypA promotes bacterial infection by upregulating TGF‐β signaling‐dependent adhesion receptor expression. Pathogens such as IAV, GAS, S. P., and K. P. induce eCypA secretion. Binding of eCypA with TβR2 enhances the affinity of TGF‐β1 and TβR2, which positively regulates adhesion receptors expression via the TGF‐β/Smad signaling pathway, thereby ...
Xiaoyuan Bai +16 more
wiley +1 more source
Characteristics and influencing factors of bronchoalveolar lavage fluid cellular patterns in children with <i>Mycoplasma pneumoniae</i> pneumonia: a cross-sectional study. [PDF]
Gao W +5 more
europepmc +1 more source
Pulmonary tumour thrombotic microangiopathy (PTTM) is a rapidly fatal condition that is rarely diagnosed during life. Early clinical recognition and prompt nivolumab treatment resulted in long‐term survival in a patient with cancer of unknown primary‐associated PTTM.
Kosuke Fujishima +4 more
wiley +1 more source
Genomic Epidemiology of Fungi Identified in Bronchoalveolar Lavage Fluid from Asthmatic Horses in the US. [PDF]
Ivester K +4 more
europepmc +1 more source

